Data/hora: 16/06/2024 19:10:34

Biblioteca(s): | Embrapa Gado de Leite.
Data corrente: | 06/09/2023
Data da última atualização: | 11/09/2023
Autoria: | DENICOL, A. C.; SIQUEIRA, L. G. B.
Afiliação: | ANNA CAROLINA DENICOL, UNIVERSITY OF CALIFORNIA; LUIZ GUSTAVO BRUNO SIQUEIRA, CNPGL.
Título: | Maternal contributions to pregnancy success: from gamete quality to uterine environment.
Ano de publicação: | 2023
Fonte/Imprenta: | Animal Reproduction, v. 20, n. 2, e202300852023, 2023.
DOI: | https://doi.org/10.1590/1984-3143-AR2023-0085
Idioma: | Inglês
Conteúdo: | The establishment and maintenance of a pregnancy that goes to term is sine qua non for the long-term sustainability of dairy and beef cattle operations. The oocyte plays a critical role in providing the factors necessary for preimplantation embryonic development. Furthermore, the female, or maternal, environment where oocytes and embryos develop is crucial for the establishment and maintenance of a pregnancy to term. During folliculogenesis, the oocyte must sequentially acquire meiotic and developmental competence, which are the results of a series of molecular events preparing the highly specialized gamete to return to totipotency after fertilization. Given that folliculogenesis is a lengthy process in the cow, the occurrence of disease, metabolic imbalances, heat stress, or other adverse events can make it challenging to maintain oocyte quality. Following fertilization, the newly formed embryo must execute a tightly planned program that includes global DNA remodeling, activation of the embryonic genome, and cell fate decisions to form a blastocyst within a few days and cell divisions. The increasing use of assisted reproductive technologies creates an additional layer of complexity to ensure the highest oocyte and embryo quality given that in vitro systems do not faithfully recreate the physiological maternal environment. In this review, we discuss cellular and molecular factors and events known to be crucial for proper oocyte development and maturation, as well as adverse events that may negatively affect the oocyte; and the importance of the uterine environment, including signaling proteins in the maternal-embryonic interactions that ensure proper embryo development. We also discuss the impact of assisted reproductive technologies in oocyte and embryo quality and developmental potential, and considerations when looking into the prospects for developing systems that allow for in vitro gametogenesis as a tool for assisted reproduction in cattle.
Palavras-Chave: | Assisted reproduction; Competência de desenvolvimento; Oócito; Reprodução assistida.
Thesagro: | Embrião Animal; Reprodução Animal.
Thesaurus Nal: | Animal reproduction; Embryo (animal); Oocytes.
Categoria do assunto: | L Ciência Animal e Produtos de Origem Animal
URL: | http://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1156457/1/Maternal-contributions-to-pregnancy-success.pdf
Registro original: | Embrapa Gado de Leite (CNPGL)
Exemplares: | CNPGL - (26096-1) - UPC - AP - DD -  -  -  - DIS