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![](/consulta/web/img/deny.png) | Acesso ao texto completo restrito à biblioteca da Embrapa Suínos e Aves. Para informações adicionais entre em contato com cnpsa.biblioteca@embrapa.br. |
Registro Completo |
Biblioteca(s): |
Embrapa Suínos e Aves. |
Data corrente: |
16/10/2015 |
Data da última atualização: |
17/02/2016 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
MOREIRA, G. C. M.; GODOY, T. F.; BOSCHIERO, C.; GHEYAS, A. A.; GASPARIN, G.; ANDRADE, S. C. S.; PADUAN, M.; MONTENEGRO, H.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L. |
Afiliação: |
GABRIEL COSTA MONTEIRO MOREIRA, ESALQ; THAYS FERNANDA GODOY, ESALQ; CLARISSA BOSCHIERO, ESALQ; ALMAS A. GHEYAS, University of Edinburgh; GUSTAVO GASPARIN, ESALQ; SONIA CRISTINA DA SILVA ANDRADE, ESALQ; MARCELA PADUAN, ESALQ; HORACIO MONTENEGRO, ESALQ; DAVID W. BURT, University of Edinburgh; MONICA CORREA LEDUR, CNPSA; LUIZ LEHMANN COUTINHO, ESALQ. |
Título: |
Variant discovery in a QTL region on chromosome 3 associated with fatness in chickens. |
Ano de publicação: |
2015 |
Fonte/Imprenta: |
Animal Genetic, v. 46, n. 2, p. 141-147, 2015. |
DOI: |
10.1111/age.12263 |
Idioma: |
Inglês |
Conteúdo: |
Abdominal fat content is an economically important trait in commercially bred chickens. Although many quantitative trait loci (QTL) related to fat deposition have been detected, the resolution for these regions is low and functional variants are still unknown. The current study was conducted aiming at increasing resolution for a region previously shown to have a QTL associated with fat deposition, to detect novel variants from this region and to annotate those variants to delineate potentially functional ones as candidates for future studies. To achieve this, 18 chickens from a parental generation used in a reciprocal cross between broiler and layer lines were sequenced using the Illumina next-generation platform with an initial coverage of 18X/chicken. The discovery of genetic variants was performed in a QTL region located on chromosome 3 between microsatellite markers LEI0161 and ADL0371 (33 595 706?42 632 651 bp). A total of 136 054 unique SNPs and 15 496 unique INDELs were detected in this region, and after quality filtering, 123 985 SNPs and 11 298 INDELs were retained. Of these variants, 386 SNPs and 15 INDELs were located in coding regions of genes related to important metabolic pathways. Loss-of-function variants were identified in several genes, and six of those, namely LOC771163, EGLN1, GNPAT, FAM120B, THBS2 and GGPS1, were related to fat deposition. Therefore, these loss-offunction variants are candidate mutations for conducting further studies on this important trait in chickens. MenosAbdominal fat content is an economically important trait in commercially bred chickens. Although many quantitative trait loci (QTL) related to fat deposition have been detected, the resolution for these regions is low and functional variants are still unknown. The current study was conducted aiming at increasing resolution for a region previously shown to have a QTL associated with fat deposition, to detect novel variants from this region and to annotate those variants to delineate potentially functional ones as candidates for future studies. To achieve this, 18 chickens from a parental generation used in a reciprocal cross between broiler and layer lines were sequenced using the Illumina next-generation platform with an initial coverage of 18X/chicken. The discovery of genetic variants was performed in a QTL region located on chromosome 3 between microsatellite markers LEI0161 and ADL0371 (33 595 706?42 632 651 bp). A total of 136 054 unique SNPs and 15 496 unique INDELs were detected in this region, and after quality filtering, 123 985 SNPs and 11 298 INDELs were retained. Of these variants, 386 SNPs and 15 INDELs were located in coding regions of genes related to important metabolic pathways. Loss-of-function variants were identified in several genes, and six of those, namely LOC771163, EGLN1, GNPAT, FAM120B, THBS2 and GGPS1, were related to fat deposition. Therefore, these loss-offunction variants are candidate mutations for conducting further studies on this important t... Mostrar Tudo |
Palavras-Chave: |
Gordura abdominal; INDEL; Mapeamento genético; QTL; SNPs. |
Thesagro: |
Cromossoma; Frango; Galinha; Genética molecular. |
Thesaurus Nal: |
Abdominal fat; Animal genetics; Chickens; Chromosome mapping; Quantitative trait loci; Single nucleotide polymorphism. |
Categoria do assunto: |
-- |
Marc: |
LEADER 02690naa a2200433 a 4500 001 2026602 005 2016-02-17 008 2015 bl uuuu u00u1 u #d 024 7 $a10.1111/age.12263$2DOI 100 1 $aMOREIRA, G. C. M. 245 $aVariant discovery in a QTL region on chromosome 3 associated with fatness in chickens.$h[electronic resource] 260 $c2015 520 $aAbdominal fat content is an economically important trait in commercially bred chickens. Although many quantitative trait loci (QTL) related to fat deposition have been detected, the resolution for these regions is low and functional variants are still unknown. The current study was conducted aiming at increasing resolution for a region previously shown to have a QTL associated with fat deposition, to detect novel variants from this region and to annotate those variants to delineate potentially functional ones as candidates for future studies. To achieve this, 18 chickens from a parental generation used in a reciprocal cross between broiler and layer lines were sequenced using the Illumina next-generation platform with an initial coverage of 18X/chicken. The discovery of genetic variants was performed in a QTL region located on chromosome 3 between microsatellite markers LEI0161 and ADL0371 (33 595 706?42 632 651 bp). A total of 136 054 unique SNPs and 15 496 unique INDELs were detected in this region, and after quality filtering, 123 985 SNPs and 11 298 INDELs were retained. Of these variants, 386 SNPs and 15 INDELs were located in coding regions of genes related to important metabolic pathways. Loss-of-function variants were identified in several genes, and six of those, namely LOC771163, EGLN1, GNPAT, FAM120B, THBS2 and GGPS1, were related to fat deposition. Therefore, these loss-offunction variants are candidate mutations for conducting further studies on this important trait in chickens. 650 $aAbdominal fat 650 $aAnimal genetics 650 $aChickens 650 $aChromosome mapping 650 $aQuantitative trait loci 650 $aSingle nucleotide polymorphism 650 $aCromossoma 650 $aFrango 650 $aGalinha 650 $aGenética molecular 653 $aGordura abdominal 653 $aINDEL 653 $aMapeamento genético 653 $aQTL 653 $aSNPs 700 1 $aGODOY, T. F. 700 1 $aBOSCHIERO, C. 700 1 $aGHEYAS, A. A. 700 1 $aGASPARIN, G. 700 1 $aANDRADE, S. C. S. 700 1 $aPADUAN, M. 700 1 $aMONTENEGRO, H. 700 1 $aBURT, D. W. 700 1 $aLEDUR, M. C. 700 1 $aCOUTINHO, L. L. 773 $tAnimal Genetic$gv. 46, n. 2, p. 141-147, 2015.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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Biblioteca(s): |
Embrapa Soja; Embrapa Trigo. |
Data corrente: |
02/12/2016 |
Data da última atualização: |
05/12/2016 |
Tipo da produção científica: |
Artigo em Anais de Congresso |
Autoria: |
SILVA, S. R.; FOLONI, J. S. S.; CUSTÓDIO, A. A. P.; BASSOI, M. C. |
Afiliação: |
SERGIO RICARDO SILVA, CNPT; JOSE SALVADOR SIMONETI FOLONI, CNPSO; Adriano Augusto de Paiva Custódio, Instituto Agronômico do Paraná (IAPAR); MANOEL CARLOS BASSOI, CNPSO. |
Título: |
Produtividade de cultivares de trigo em função de fontes e épocas de aplicação de nitrogênio. |
Ano de publicação: |
2016 |
Fonte/Imprenta: |
In: REUNIÃO DA COMISSÃO BRASILEIRA DE PESQUISA DE TRIGO E TRITICALE, 10., 2016, Londrina. Anais... Londrina: Comissão Brasileira de Pesquisa de Trigo e Triticale, 2016. 1 CD-ROM. |
Páginas: |
5 p. |
Descrição Física: |
1 CD-ROM. |
Idioma: |
Português |
Palavras-Chave: |
Cultivar; Nitogênio; Variety. |
Thesagro: |
Trigo; Triticale; Variedade. |
Thesaurus NAL: |
Nitrogen; Wheat. |
Categoria do assunto: |
-- F Plantas e Produtos de Origem Vegetal |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/151081/1/95.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/158828/1/ID44040-2016RCBPTT10SERGIO95.pdf
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Marc: |
LEADER 00822nam a2200241 a 4500 001 2057754 005 2016-12-05 008 2016 bl uuuu u00u1 u #d 100 1 $aSILVA, S. R. 245 $aProdutividade de cultivares de trigo em função de fontes e épocas de aplicação de nitrogênio.$h[electronic resource] 260 $aIn: REUNIÃO DA COMISSÃO BRASILEIRA DE PESQUISA DE TRIGO E TRITICALE, 10., 2016, Londrina. Anais... Londrina: Comissão Brasileira de Pesquisa de Trigo e Triticale, 2016. 1 CD-ROM.$c2016 300 $a5 p.$c1 CD-ROM. 650 $aNitrogen 650 $aWheat 650 $aTrigo 650 $aTriticale 650 $aVariedade 653 $aCultivar 653 $aNitogênio 653 $aVariety 700 1 $aFOLONI, J. S. S. 700 1 $aCUSTÓDIO, A. A. P. 700 1 $aBASSOI, M. C.
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