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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sul. Para informações adicionais entre em contato com cppsul.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sul. |
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Data corrente: |
21/10/2021 |
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Data da última atualização: |
21/10/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
GASPAR, E. B.; PRUDENCIO, C. R.; DE GASPARI, E. |
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Afiliação: |
EMANUELLE BALDO GASPAR, CPPSUL; CARLOS ROBERTO PRUDENCIO; ELIZABETH DE GASPARI. |
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Título: |
Experimental studies using OMV in a new platform of SARS-CoV-2 vaccines. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Human Vaccines & Immunotherapeutics, v. 17, n. 9, p. 2965-2968, May 2021. |
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Idioma: |
Inglês |
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Conteúdo: |
Although COVID-19 vaccines have recently been approved for emergency use, search for new vaccines are still urgent, since the access of the countries, especially the poorest, to the vaccines, has shown to be slower than the necessary to rapidly control the pandemic. We proposed a novel platform for vaccine using recombinant receptor binding domain (rRBD) from Sars-Cov-2 spike protein and Neisseria meningitidis outer membrane vesicles (OMVs). The antigen preparation produced a humoral and cellular immune response. Taken together our findings suggest a good immunostimulatory patter in response to immunization with rRBD plus N. meningitidis OMV. |
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Palavras-Chave: |
Coronavírus; Covid-19; SARS-Cov-2. |
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Thesagro: |
Doença; Imunidade; Vírus. |
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Categoria do assunto: |
-- |
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Marc: |
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100 1 $aGASPAR, E. B.
245 $aExperimental studies using OMV in a new platform of SARS-CoV-2 vaccines.$h[electronic resource]
260 $c2021
520 $aAlthough COVID-19 vaccines have recently been approved for emergency use, search for new vaccines are still urgent, since the access of the countries, especially the poorest, to the vaccines, has shown to be slower than the necessary to rapidly control the pandemic. We proposed a novel platform for vaccine using recombinant receptor binding domain (rRBD) from Sars-Cov-2 spike protein and Neisseria meningitidis outer membrane vesicles (OMVs). The antigen preparation produced a humoral and cellular immune response. Taken together our findings suggest a good immunostimulatory patter in response to immunization with rRBD plus N. meningitidis OMV.
650 $aDoença
650 $aImunidade
650 $aVírus
653 $aCoronavírus
653 $aCovid-19
653 $aSARS-Cov-2
700 1 $aPRUDENCIO, C. R.
700 1 $aDE GASPARI, E.
773 $tHuman Vaccines & Immunotherapeutics$gv. 17, n. 9, p. 2965-2968, May 2021.
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