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1. | | HONG, J.; KIM, D.; CHO, K.; SA, S.; CHOI, S.; KIM, Y.; PARK, J.; SCHMIDT, G. S.; DAVIS, M. E.; CHUNG, H. Effects of genetic variants for the swine FABP3, HMGA1, MC4R, IGF2, and FABP4 genes on fatty acid composition. Meat Science, v. 110, p. 46-51, 2015. Biblioteca(s): Embrapa Suínos e Aves. |
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Registros recuperados : 1 | |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Suínos e Aves. Para informações adicionais entre em contato com cnpsa.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Suínos e Aves. |
Data corrente: |
14/12/2015 |
Data da última atualização: |
14/12/2015 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
HONG, J.; KIM, D.; CHO, K.; SA, S.; CHOI, S.; KIM, Y.; PARK, J.; SCHMIDT, G. S.; DAVIS, M. E.; CHUNG, H. |
Afiliação: |
JOONKI HONG, National Institute of Animal Science/Swine Science Division; DUWAN KIM, National Institute of Animal Science/Swine Science Division; KYUHO CHO, National Institute of Animal Science/Swine Science Division; SOOJIN SA, National Institute of Animal Science/Swine Science Division; SUNHO CHOI, National Institute of Animal Science/Swine Science Division; YOUNGHWA KIM, National Institute of Animal Science/Swine Science Division; JUNCHEOL PARK, National Institute of Animal Science/Swine Science Division; GILBERTO SILBER SCHMIDT, SRI; MICHAEL E. DAVIS, The Ohio State University, Department of Animal Sciences; HOYOUNG CHUNG, National Institute of Animal Science/Animal Genomics and Bioinformatics Division. |
Título: |
Effects of genetic variants for the swine FABP3, HMGA1, MC4R, IGF2, and FABP4 genes on fatty acid composition. |
Ano de publicação: |
2015 |
Fonte/Imprenta: |
Meat Science, v. 110, p. 46-51, 2015. |
DOI: |
http://dx.doi.org/10.1016/j.meatsci.2015.06.011 |
Idioma: |
Inglês |
Conteúdo: |
This study aimed to verify genetic relationships between fatty acid composition (FAC) and genotypes of several genes (FABP3, HMGA1, MC4R, IGF2, and FABP4) using pig breeds. The effects of genetic variations on FAC of the longissimus muscle were statistically significant with additive and dominance effects. The polymorphisms of FABP3 and IGF2 had the largest effects on stearic (C18:0, P = 0.009) and γ-linoleic (C18:3n6, P = 0.039) acids, respectively, whereasHMGA1 and FABP4 did not show significances. The analysis revealed that MC4R was significantly associated with palmitoleic acid (C16:ln7) and MUFA. Allele frequencies of the genes examined in this analysis were significantly skewed or fixed in the Korean native pig (KNP), whereas the allele frequencies of the crossbreds tended to fall between those of the purebreds except that HMGA1 and FABP4 had approximately the same allele frequencies with Duroc and KNP, respectively. The polymorphisms found in this study could be used as genetic markers in breeding programs to simultaneously change proportions of fatty acids in muscle tissues. |
Palavras-Chave: |
Composição de ácidos graxos. |
Thesagro: |
Melhoramento genético animal; Polimorfismo genético; Suíno. |
Thesaurus NAL: |
Animal genetics; fatty acid composition; Single nucleotide polymorphism; Swine. |
Categoria do assunto: |
-- |
Marc: |
LEADER 02088naa a2200337 a 4500 001 2031626 005 2015-12-14 008 2015 bl uuuu u00u1 u #d 024 7 $ahttp://dx.doi.org/10.1016/j.meatsci.2015.06.011$2DOI 100 1 $aHONG, J. 245 $aEffects of genetic variants for the swine FABP3, HMGA1, MC4R, IGF2, and FABP4 genes on fatty acid composition.$h[electronic resource] 260 $c2015 520 $aThis study aimed to verify genetic relationships between fatty acid composition (FAC) and genotypes of several genes (FABP3, HMGA1, MC4R, IGF2, and FABP4) using pig breeds. The effects of genetic variations on FAC of the longissimus muscle were statistically significant with additive and dominance effects. The polymorphisms of FABP3 and IGF2 had the largest effects on stearic (C18:0, P = 0.009) and γ-linoleic (C18:3n6, P = 0.039) acids, respectively, whereasHMGA1 and FABP4 did not show significances. The analysis revealed that MC4R was significantly associated with palmitoleic acid (C16:ln7) and MUFA. Allele frequencies of the genes examined in this analysis were significantly skewed or fixed in the Korean native pig (KNP), whereas the allele frequencies of the crossbreds tended to fall between those of the purebreds except that HMGA1 and FABP4 had approximately the same allele frequencies with Duroc and KNP, respectively. The polymorphisms found in this study could be used as genetic markers in breeding programs to simultaneously change proportions of fatty acids in muscle tissues. 650 $aAnimal genetics 650 $afatty acid composition 650 $aSingle nucleotide polymorphism 650 $aSwine 650 $aMelhoramento genético animal 650 $aPolimorfismo genético 650 $aSuíno 653 $aComposição de ácidos graxos 700 1 $aKIM, D. 700 1 $aCHO, K. 700 1 $aSA, S. 700 1 $aCHOI, S. 700 1 $aKIM, Y. 700 1 $aPARK, J. 700 1 $aSCHMIDT, G. S. 700 1 $aDAVIS, M. E. 700 1 $aCHUNG, H. 773 $tMeat Science$gv. 110, p. 46-51, 2015.
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Embrapa Suínos e Aves (CNPSA) |
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