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| Registros recuperados : 10 | |
| 1. |  | ZUMÁRRAGA, M. J.; CATALDI, A.; ARAUJO, F. R.; DIB, C. C.; ROXO, E. Caracterização genética de Mycobacterium bovis em animais de cinco estados brasileiros. O Biológico, São Paulo, SP, v. 74, n. 2, p 95 , jul./dez. 2012. Edição dos resumos da 25ª Reunião Anual do Instituto Biológico, São Paulo, 2012 e 10º Congresso de Iniciação Científica em Ciências Agrárias Biológicas e Ambientais - CICAM, agosto, 2012. Resumo 09.| Biblioteca(s): Embrapa Gado de Corte. |
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| 2. | | VIALE, M. N.; ZUMÁRRAGA, M. J.; ARAUJO, F. R.; ZARRAGA, A. M.; CATALDI, A. A.; ROMANO, M. I.; BIGI, F. La genómica de las micobacterias. Revue scientifique et technique (International Office des Epizooties), v. 35, v. 1, p. 215-227, 2016.| Biblioteca(s): Embrapa Gado de Corte. |
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| 3. | | CASTELÃO, A. B. C.; NISHIBE, C.; ZUMÁRRAGA, M. J; CATALDI, A. A.; BIGGI, F; FONSECA JR, A. A.; HODON, M. A; ALMEIDA, N. F.; ARAUJO, F. R. Comparação de genes de virulência de dois isolados de Mycobacterium Bovis sequenciados por plataforma de nova geração. In: JORNADA CIENTÍFICA EMBRAPA GADO DE CORTE, 10., 2014, Campo Grande, MS. [Anais da..]. Campo Grande, MS: Embrapa Gado de Corte, 2014. p.14-15. 2 p. (Embrapa Gado de Corte. Documentos, 208). Comissão organizadora: Grácia Maria Soares Rosinha, Alexandra Rocha de Oliveir, Rodrigo Carvalho Alva.| Biblioteca(s): Embrapa Gado de Corte. |
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| 4. | | CASTELÃO, A. B. C.; NISHIBE, C.; ZUMÁRRAGA, M. J.; CATALDI, A.; BIGI, F.; RAMOS, C. A. do N.; ALMEIDA, V. F.; ARAUJO, F. R. Comparação de genes de virulência de duas cepas de Mycobacterium bovis com perfis patogênicos contrastantes. Campo Grande, MS: Embrapa Gado de Corte, 2015 ( Embrapa Gado de Corte. Boletim de Pesquisa e Desenvolvimento, 33)| Biblioteca(s): Embrapa Gado de Corte. |
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| 5. | | GUERRERO, E. B.; ARNEODO, J.; GIOFFRÉ, A.; CAMPOS, E.; ETCHEVERRY; GODOY, C.; SALUM, T. F. C.; DAMASO, M. C. T.; CATALDI, A.; TALIA, P. Identificación y evaluación de celulasas y hemicelulsas en el intestino de dos termitas nativas para la obtencion de bioetanol. In: ENCUENTRO LATINOAMERICANO Y DEL CARIBE DE BIOTECNOLOGÍA, 8., 2013, Buenos Aires, Argentina. Abstracts. Argentina: RedBio, 2013.| Biblioteca(s): Embrapa Agroenergia. |
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| 6. | | BIGI, M. M.; BLANCO, F. C.; ARAUJO, F. R.; THACKER, T. C.; ZUMÁRRAGA, M. J.; CATALDI, A. A.; SORIA, M. A.; BIGI, F. Polymorphisms of 20 regulatory proteins between Mycobacterium tuberculosis and Mycobacterium bovis. Microbiology and Immunology, v. 60, n. 8, p. 552-560, August 2016| Biblioteca(s): Embrapa Gado de Corte. |
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| 7. | | NISHIBE, C.; CASTELÃO, A. B. C.; COSTA, R. D.; PINTO, B. J.; VARUZZA, L.; CATALDI, A. A.; BERNARDELLI, A.; BIGI, F.; BLANCO, F. C.; ZUMÁRRAGA, M. J.; ALMEIDA, N. F.; ARAUJO, F. R. Draft Genome Sequence of Mycobacterium bovis 04-303, a Highly Virulent Strain from Argentina. Genome Announcements, v. 1, n. 6, p. 1-2, 2013.| Biblioteca(s): Embrapa Gado de Corte. |
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| 8. | | GUERRERO, E. B.; ARNEODO, J.; CAMPANHA, R. B.; OLIVEIRA, P. A. de; LABARTE, M. T. V.; CATALDI, T. R.; CAMPOS, E.; CATALDI, A.; LABARTE, C. A.; RODRIGUES, C. M.; TALIA, P. Prospection and evaluation of (Hemi) cellulolytic enzymes using untreated and pretreated biomasses in two argentinean native termites. PLoS ONE, v. 10, n. 8, p1-23. 23p, 2015| Biblioteca(s): Embrapa Agroenergia. |
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| 9. | | BIGI, M.; VAZQUEZ, C. L.; CASTELÃO, A. B. C.; GARCÍA, E. A.; CATALDI, A. A.; JACKSON, M.; MAcNEIL, M.; SORIA, M.; ZUMÁRRAGA, M. J.; MATIAS, C.; GAGO, G.; BLANCO, F. C.; NISHIBEF, C.; ALMEIDA, N. F.; ARAUJO, F. R.; BIGI, F. Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles. Veterinary Microbiology, v. 239, 2019.| Biblioteca(s): Embrapa Gado de Corte. |
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| 10. | | PATANE, J. S. L.; MARTINS JUNIOR, J.; CASTELÃO, A. B.; NISHIBE, C.; MONTERA, L.; BIGI, F.; ZUMÁRRAGA, M. J.; CATALDI, A. A.; FONSECA JUNIOR, A.; ROXO, E.; OSÓRIO, A. L. A. R.; JORGE, K. S.; THACKER, T. C.; ALMEIDA, N. F.; ARAUJO, F. R.; SETUBAL, J. C. Patterns and Processes of Mycobacterium bovis Evolution Revealed by Phylogenomic Analyses. Genome Biology and Evolution, v. 9, n. 3, p. 521-535, March 2017.| Biblioteca(s): Embrapa Gado de Corte. |
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| Registros recuperados : 10 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Gado de Corte. |
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Data corrente: |
13/10/2017 |
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Data da última atualização: |
26/10/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
PATANE, J. S. L.; MARTINS JUNIOR, J.; CASTELÃO, A. B.; NISHIBE, C.; MONTERA, L.; BIGI, F.; ZUMÁRRAGA, M. J.; CATALDI, A. A.; FONSECA JUNIOR, A.; ROXO, E.; OSÓRIO, A. L. A. R.; JORGE, K. S.; THACKER, T. C.; ALMEIDA, N. F.; ARAUJO, F. R.; SETUBAL, J. C. |
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Afiliação: |
José S. L. Patane, Departamento de Bioquímica/Instituto de Química, Universidade de São Paulo; Joaquim Martins Jr, Departamento de Bioquímica/Instituto de Química, Universidade de São Paulo; Ana Beatriz Castelão, Universidade Federal de Mato Grosso do Sul - UFMS; Christiane Nishibe, Faculdade de Computação/Universidade Federal de Mato Grosso do Sul - UFMS; Luciana Montera, Faculdade de Computacão Universidade Federal de Mato Grosso do Sul - UFMS; Fabiana Bigi, Instituto Nacional de Tecnologia Agropecuária de Córdoba; Martin J. Zumárraga, Instituto Nacional de Tecnologia Agropecuária de Córdoba; Angel A. Cataldi, Instituto Nacional de Tecnologia Agropecuária de Córdoba; Antônio Fonseca Junior, Rede de Laboratórios Agropecuários do Ministério da Agricultura, Pecuária e Abastecimento; Eliana Roxo, Instituto Biológico de São Paulo, IB-USP; Ana Luiza A. R. Osório, Programa em Ciência Animal Universidade Federal de Mato Grosso do Sul; Klaudia S. Jorge, Programa em Ciência Animal Universidade Federal de Mato Grosso do Sul; Tyler C. Thacker, Agricultural Research Service, United States Department of Agriculture; Nalvo F. Almeida, Faculdade de Computação Universidade Federal de Mato Grosso do Sul; FLABIO RIBEIRO ARAUJO, CNPGC; João C. Setubal, Biocomplexity Institute of Virginia Tech. |
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Título: |
Patterns and Processes of Mycobacterium bovis Evolution Revealed by Phylogenomic Analyses. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Genome Biology and Evolution, v. 9, n. 3, p. 521-535, March 2017. |
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DOI: |
10.1093/gbe/evx022 |
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Idioma: |
Inglês |
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Conteúdo: |
Mycobacterium bovis is an important animal pathogen worldwide that parasitizes wild and domesticated vertebrate livestock as well as humans. A comparison of the five M. bovis complete genomes from the United Kingdom, South Korea, Brazil, and the United States revealed four novel large-scale structural variations of at least 2,000 bp.Acomparative phylogenomic study including 2,483 core genes of 38 taxa from eight countries showed conflicting phylogenetic signal among sites. By minimizing this effect,we obtained a tree that better agreeswith sampling locality. Results supported a relatively basal position of African strains (all isolated from Homo sapiens), confirming that Africa was an important region for early diversification and that humans were one of the earliest hosts. Selection analyses revealed that functional categories such as ?Lipid transport and metabolism,? ?Cell cycle control, cell division, chromosome partitioning? and ?Cell motility? were significant for the evolution of the group, besides other categories previously described, showing importance of genes associated with virulence and cholesterolmetabolism in the evolution of M. bovis. PE/PPE genes,many ofwhich are known to be associated with virulence, were major targets for large-scale polymorphisms, homologous recombination, and positive selection, evincing for the first time a plethora of evolutionary forces possibly contributing to differential adaptability in M. bovis. By assuming different priors, US strains originated and started to diversify around 150?5,210 ya. By further analyzing the largest set of US genomes to date (76 in total), obtained from 14 host species,we detected that hosts were not clustered in clades (except for a few cases), with some faster-evolving strains being detected, suggesting fast and ongoing reinfections across host species, and therefore, the possibility of new bovine tuberculosis outbreaks. MenosMycobacterium bovis is an important animal pathogen worldwide that parasitizes wild and domesticated vertebrate livestock as well as humans. A comparison of the five M. bovis complete genomes from the United Kingdom, South Korea, Brazil, and the United States revealed four novel large-scale structural variations of at least 2,000 bp.Acomparative phylogenomic study including 2,483 core genes of 38 taxa from eight countries showed conflicting phylogenetic signal among sites. By minimizing this effect,we obtained a tree that better agreeswith sampling locality. Results supported a relatively basal position of African strains (all isolated from Homo sapiens), confirming that Africa was an important region for early diversification and that humans were one of the earliest hosts. Selection analyses revealed that functional categories such as ?Lipid transport and metabolism,? ?Cell cycle control, cell division, chromosome partitioning? and ?Cell motility? were significant for the evolution of the group, besides other categories previously described, showing importance of genes associated with virulence and cholesterolmetabolism in the evolution of M. bovis. PE/PPE genes,many ofwhich are known to be associated with virulence, were major targets for large-scale polymorphisms, homologous recombination, and positive selection, evincing for the first time a plethora of evolutionary forces possibly contributing to differential adaptability in M. bovis. By assuming different priors, US st... Mostrar Tudo |
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Palavras-Chave: |
Família PE / PPE; Filogenômica; Phylogenomics; Tuberculose bovina. |
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Thesagro: |
Epidemiologia; Mycobacterium Bovis; Patogenicidade; Patógeno; Polimorfismo; Tuberculose. |
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Thesaurus NAL: |
Bovine tuberculosis. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/165055/1/Patterns-and-processes-of-Mycobacterium-bovis.pdf
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Marc: |
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024 7 $a10.1093/gbe/evx022$2DOI
100 1 $aPATANE, J. S. L.
245 $aPatterns and Processes of Mycobacterium bovis Evolution Revealed by Phylogenomic Analyses.$h[electronic resource]
260 $c2017
520 $aMycobacterium bovis is an important animal pathogen worldwide that parasitizes wild and domesticated vertebrate livestock as well as humans. A comparison of the five M. bovis complete genomes from the United Kingdom, South Korea, Brazil, and the United States revealed four novel large-scale structural variations of at least 2,000 bp.Acomparative phylogenomic study including 2,483 core genes of 38 taxa from eight countries showed conflicting phylogenetic signal among sites. By minimizing this effect,we obtained a tree that better agreeswith sampling locality. Results supported a relatively basal position of African strains (all isolated from Homo sapiens), confirming that Africa was an important region for early diversification and that humans were one of the earliest hosts. Selection analyses revealed that functional categories such as ?Lipid transport and metabolism,? ?Cell cycle control, cell division, chromosome partitioning? and ?Cell motility? were significant for the evolution of the group, besides other categories previously described, showing importance of genes associated with virulence and cholesterolmetabolism in the evolution of M. bovis. PE/PPE genes,many ofwhich are known to be associated with virulence, were major targets for large-scale polymorphisms, homologous recombination, and positive selection, evincing for the first time a plethora of evolutionary forces possibly contributing to differential adaptability in M. bovis. By assuming different priors, US strains originated and started to diversify around 150?5,210 ya. By further analyzing the largest set of US genomes to date (76 in total), obtained from 14 host species,we detected that hosts were not clustered in clades (except for a few cases), with some faster-evolving strains being detected, suggesting fast and ongoing reinfections across host species, and therefore, the possibility of new bovine tuberculosis outbreaks.
650 $aBovine tuberculosis
650 $aEpidemiologia
650 $aMycobacterium Bovis
650 $aPatogenicidade
650 $aPatógeno
650 $aPolimorfismo
650 $aTuberculose
653 $aFamília PE / PPE
653 $aFilogenômica
653 $aPhylogenomics
653 $aTuberculose bovina
700 1 $aMARTINS JUNIOR, J.
700 1 $aCASTELÃO, A. B.
700 1 $aNISHIBE, C.
700 1 $aMONTERA, L.
700 1 $aBIGI, F.
700 1 $aZUMÁRRAGA, M. J.
700 1 $aCATALDI, A. A.
700 1 $aFONSECA JUNIOR, A.
700 1 $aROXO, E.
700 1 $aOSÓRIO, A. L. A. R.
700 1 $aJORGE, K. S.
700 1 $aTHACKER, T. C.
700 1 $aALMEIDA, N. F.
700 1 $aARAUJO, F. R.
700 1 $aSETUBAL, J. C.
773 $tGenome Biology and Evolution$gv. 9, n. 3, p. 521-535, March 2017.
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