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Registros recuperados : 4 | |
1. | | FARAH, M. M.; FORTES, M. R. S.; KELLY, M.; POTO-NETO, L. R.; MEIRA, C. T.; CARREÑO, L. O. D.; FONSECA, R. da; MOORE, S. S. Accuracy of genomic selection predictions for hip height in Brahman cattle using different relationship matrices. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 53, n. 6, p. 717-726, June, 2018. Título em português: Acurácia da predição genômica para altura do quadril em bovinos Brahman com uso de diferentes matrizes de parentesco. Biblioteca(s): Embrapa Unidades Centrais. |
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2. | | CAVANI, L.; SILVA, R. M. de O.; CARREÑO, L. O. D.; ONO, R. K.; BERTIPAGLIA, T. S.; FARAH, M. M.; MILLEN, D. D.; FONSECA, R. da. Genetic diversity of Brazilian Brahman cattle by pedigree analysis. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 53, n. 1, p. 74-79, jan. 2018. Título em inglês: Diversidade genética de bovinos Brahman no Brasil por meio da análise de pedigree. Biblioteca(s): Embrapa Unidades Centrais. |
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3. | | ROCHA, G. M. DE F.; FERREIRA, T. A.; PIRES, A. V.; SILVA, M. V. G. B.; ARAUJO, C. V. DE; CARRENO, L. O. D. Herdabilidade para caracteristicas leiteiras em bovinos da raça Girolando. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 10., 2013, Uberaba. Anais... Viçosa: Sociedade Brasileira de Melhoramento Animal, 2013. Biblioteca(s): Embrapa Gado de Leite. |
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4. | | RODRIGUES, A. F. G.; IBELLI, A. M. G.; PEIXOTO, J. de O.; CANTAO, M. E.; OLIVEIRA, H. C. de; SAVOLDI, I. R.; SOUZA, M. R.; MORES, M. A. Z.; CARREÑO, L. O. D.; LEDUR, M. C. Genes and SNPs Involved with Scrotal and Umbilical Hernia in Pigs. Genes, v. 12, n. 166, 2021. Biblioteca(s): Embrapa Suínos e Aves. |
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Registros recuperados : 4 | |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Suínos e Aves. Para informações adicionais entre em contato com cnpsa.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Suínos e Aves. |
Data corrente: |
12/02/2021 |
Data da última atualização: |
12/02/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
RODRIGUES, A. F. G.; IBELLI, A. M. G.; PEIXOTO, J. de O.; CANTAO, M. E.; OLIVEIRA, H. C. de; SAVOLDI, I. R.; SOUZA, M. R.; MORES, M. A. Z.; CARREÑO, L. O. D.; LEDUR, M. C. |
Afiliação: |
ARIENE FERNANDA GRANDO RODRIGUES, UDESC/Chapecó; ADRIANA MERCIA GUARATINI IBELLI, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; MAURICIO EGIDIO CANTAO, CNPSA; HANIEL CEDRAZ DE OLIVEIRA, UFV; IGOR RICARDO SAVOLDI, UDESC/Chapecó; MAYLA REGINA SOUZA, UFRGS; MARCOS ANTONIO ZANELLA MORES, CNPSA; LUIS ORLANDO DUITAMA CARREÑO, BRF/Curitiba; MONICA CORREA LEDUR, CNPSA. |
Título: |
Genes and SNPs Involved with Scrotal and Umbilical Hernia in Pigs. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Genes, v. 12, n. 166, 2021. |
DOI: |
https://doi.org/10.3390/genes12020166 |
Idioma: |
Inglês |
Conteúdo: |
Abstract: Hernia is one of the most common defects in pigs. The most prevalent are the scrotal (SH), inguinal (IH) and umbilical (UH) hernias. We compared the inguinal ring transcriptome of normal and SH-affected pigs with the umbilical ring transcriptome of normal and UH-affected pigs to discover genes and pathways involved with the development of both types of hernia. A total of 13,307 transcripts was expressed in the inguinal and 13,302 in the umbilical ring tissues with 94.91% of them present in both tissues. From those, 35 genes were differentially expressed in both groups, participating in 108 biological processes. A total of 67 polymorphisms was identified in the inguinal ring and 76 in the umbilical ring tissue, of which 11 and 14 were novel, respectively. A single nucleotide polymorphism (SNP) with deleterious function was identified in the integrin α M (ITGAM) gene. The microtubule associated protein 1 light chain 3 (MAP1LC3C), vitrin (VIT), aggrecan (ACAN), alkaline ceramidase 2 (ACER2), potassium calcium-activated channel subfamily M 1 (KCNMA1) and synaptopodin 2 (SYNPO2) genes are highlighted as candidates to trigger both types of hernia. We generated the first comparative study of the pig umbilical and inguinal ring transcriptomes, contributing to the understanding of the genetic mechanism involved with these two types of hernia in pigs and probably in other mammals. |
Palavras-Chave: |
Congenital defects; Defeitos congênitos; Expressão genetica; RNA-Seq. |
Thesagro: |
Melhoramento Genético Animal; Suíno. |
Thesaurus NAL: |
Gene expression; Swine; Transcriptomics. |
Categoria do assunto: |
-- |
Marc: |
LEADER 02388naa a2200349 a 4500 001 2130032 005 2021-02-12 008 2021 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.3390/genes12020166$2DOI 100 1 $aRODRIGUES, A. F. G. 245 $aGenes and SNPs Involved with Scrotal and Umbilical Hernia in Pigs.$h[electronic resource] 260 $c2021 520 $aAbstract: Hernia is one of the most common defects in pigs. The most prevalent are the scrotal (SH), inguinal (IH) and umbilical (UH) hernias. We compared the inguinal ring transcriptome of normal and SH-affected pigs with the umbilical ring transcriptome of normal and UH-affected pigs to discover genes and pathways involved with the development of both types of hernia. A total of 13,307 transcripts was expressed in the inguinal and 13,302 in the umbilical ring tissues with 94.91% of them present in both tissues. From those, 35 genes were differentially expressed in both groups, participating in 108 biological processes. A total of 67 polymorphisms was identified in the inguinal ring and 76 in the umbilical ring tissue, of which 11 and 14 were novel, respectively. A single nucleotide polymorphism (SNP) with deleterious function was identified in the integrin α M (ITGAM) gene. The microtubule associated protein 1 light chain 3 (MAP1LC3C), vitrin (VIT), aggrecan (ACAN), alkaline ceramidase 2 (ACER2), potassium calcium-activated channel subfamily M 1 (KCNMA1) and synaptopodin 2 (SYNPO2) genes are highlighted as candidates to trigger both types of hernia. We generated the first comparative study of the pig umbilical and inguinal ring transcriptomes, contributing to the understanding of the genetic mechanism involved with these two types of hernia in pigs and probably in other mammals. 650 $aGene expression 650 $aSwine 650 $aTranscriptomics 650 $aMelhoramento Genético Animal 650 $aSuíno 653 $aCongenital defects 653 $aDefeitos congênitos 653 $aExpressão genetica 653 $aRNA-Seq 700 1 $aIBELLI, A. M. G. 700 1 $aPEIXOTO, J. de O. 700 1 $aCANTAO, M. E. 700 1 $aOLIVEIRA, H. C. de 700 1 $aSAVOLDI, I. R. 700 1 $aSOUZA, M. R. 700 1 $aMORES, M. A. Z. 700 1 $aCARREÑO, L. O. D. 700 1 $aLEDUR, M. C. 773 $tGenes$gv. 12, n. 166, 2021.
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