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| Registros recuperados : 174 | |
| 141. |  | DOS SANTOS, C. P.; BATISTA, M. C.; SARAIVA, K. D. DA C.; ROQUE, A. L. M.; MIRANDA, R. DE S.; SILVA, L. M. A. E; MOURA, C. F. H.; FILHO, E. G. A.; CANUTO, K. M.; JOSÉ HÉLIO COSTA. Transcriptome analysis of acerola fruit ripening. Insights into ascorbate, ethylene, respiration, and softening metabolisms Plant Molecular Biology, Dordrecht, v. 101, n. 3, p. 269-296, Oct. 2019.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 142. | | KELLER, L.; CANUTO, K. M.; LIU, C.; SUZUKI, B. M.; ALMALITI, J.; SIKANDAR, A.; NAMAN, C. B.; GLUKHOV, E.; LUO, D.; DUGGAN, B. M.; LUESCH, H.; KOEHNKE, J.; O'DONOGHUE, A. J.; GERWICK, W. H. Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties. ACS Chemical Biology, v. 15, n. 3, p. 751-757, 2020.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 143. | | RODRIGUES, T. H. S.; CANUTO, K. M.; PEREIRA, R. de C. A.; BRITO, E. S. de; VIEIRA, R. F.; RIBEIRO, P. R. V.; SOUSA, A. D.; MAIA, A. I. V. Ultrasound-assisted and pressurized liquid extraction of phenolic compounds from Phyllanthus amarus and its composition evaluation by UPLC-QTOF. Industrial Crops and Products, v. 79, p. 91-103, 2016.| Biblioteca(s): Embrapa Agroindústria Tropical; Embrapa Recursos Genéticos e Biotecnologia. |
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| 144. | | SOUZA, A. S. DE Q.; SOUSA, J. A. C. DE; PINTO, C. S.; ALVES FILHO, E. G.; PEREIRA, R. de C. A.; BRITO, E. S. de; CANUTO, K. M.; LEAL, L. K. A. M. Untargeted GC/MS-based approach for identification of anti-inflammatory alkaloids from Hippeastrum elegans (Amaryllidaceae) using a human neutrophil model. Journal of Pharmaceutical and Biomedical Analysis, v. 199, 114061, 2021.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 146. | | MORAES, I. V. M. de; RIBEIRO, P. R. V.; SCHMIDT, F. L.; CANUTO, K. M.; ZOCOLO, G. J.; BRITO, E. S. de; LUO, R.; RICHARDS, K. M.; TRAN, K.; Smith, R. E. UPLC-QTOF-MS and NMR analyses of graviola (Annona muricata) leaves. Revista Brasileira de Farmacognosia, v. 26, n. 2, p. 174-179, 2016.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 147. | | CARRETO, D. A. S.; BATISTA, P. H. J.; SOUZA, L. G. S.; PINTO, F. C. L.; VASCONCELOS, M. A.; TEIXEIRA, E. H.; CANUTO, K. M.; SANTIAGO, G. M. P.; SILVEIRA, E. R.; PESSOA, O. D. L. Withanolides from Leaves of Nicandra physalodes. Journal of the Brazilian Chemical Society, v. 29, n. 1, p. 11-16, 2018.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 148. | | DA SILVA, A. B.; SILVEIRA, E. R.; WILKE, D. V.; FERREIRA, E. G.; LOTUFO, L. V. C.; TORRES, M. C. M.; AYALA, A. P.; COSTA, W. S.; CANUTO, K. M.; NOBRE, A. R. DE A.; ARAÚJO, A. J.; MARINHO FILHO, J. D. B.; PESSOA, O. D. L. Antibacterial Salinaphthoquinones from a Strain of the Bacterium Salinispora arenicola Recovered from the Marine Sediments of St. Peter and St. Paul Archipelago, Brazil. Journal of Natural Products, Washington, DC, v. 82, n. 7, p. 1831-1838, 26 July 2019.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 149. | | LIMA, L. F. DE; ANDRADE-PINHEIRO, J. C.; FREITAS, M. A.; SILVA, A. I. DA; FONSECA, V. J. A.; SILVA, T. G. DA; SILVA, J. C. P. DA; LIMA, R. H. DE; SALES, D. L.; NEVES, R. P.; BRITO, E. S. de; RIBEIRO, P. R. V.; CANUTO, K. M.; COUTINHO, H. D. M.; SIYADATPANAH, A.; KIM, B.; MORAIS-BRAGA, M. F. B. Anti-Candida properties of Gossypium hirsutum L.: enhancement of fungal growth, biofilm production and antifungal resistance. Pharmaceutics, v. 14, n. 698, 2022. 18 p.| Biblioteca(s): Embrapa Agroindústria Tropical; Embrapa Alimentos e Territórios. |
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| 150. | | PEDRA, N. S.; GALDINO, K. C. A.; SILVA, D. S.; RAMOS, P. T.; BONA, N. P.; SOARES, M. S. P.; AZAMBUJA, J. H.; CANUTO, K. M.; BRITO, E. S. de; RIBEIRO, P. R. V.; SOUZA, A. S. de Q.; CUNICO, W.; STEFANELLO, F. M.; SPANEVELLO, R. M.; BRAGANHOL, E. Endophytic Fungus Isolated From Achyrocline satureioides Exhibits Selective Antiglioma Activity - The Role of Sch-642305. Frontiers in Oncology, v. 8, art. 476, 2018.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 151. | | ARAUJO, T. D. S.; RIBEIRO, F. de O. S.; ARAUJO-NOBRE, A. R. de; NADVORNY, D.; CANUTO, K. M.; PEREIRA, R. de C. A.; SOUZA, A. S. de Q.; BRITO, A. L. de C.; MENEZES, F. G. R. de; SILVA, A. L. C. DA; FOGACA, F. H. dos S.; SILVA, D. A. DA; SOUZA, B. W. S. DE. Effectiveness of a formulation based on Ocimum gratissimum essential oil and cashew gum as inhibitors of quality loss and melanosis in shrimp. International Journal of Biological Macromolecules, 268, 131661, 2024.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 152. | | MAGALHÃES, H. S.; SILVA, A. B. da; NASCIMENTO, N. R. F.; SOUSA, L. G. F. de; FONSECA, M. J. S. da; LOIOLA, M. I. B.; MONTEIRO, N. K. V.; ALMEIDA NETO, F. W. Q.; CANUTO, K. M.; PESSOA, O. D. L. Effect of indole alkaloids from roots of Rauvolfia ligustrina in the noradrenergic neurotransmission. Fitoterapia, 143, art. no. 104545,2020.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 153. | | GUEDES, J. A. C.; ALVES FILHO, E. G.; RODRIGUES, T. H. S.; SILVA, M. F. S.; SOUZA, F. V. D.; SILVA, L. M. A. e; ALVES, R. E.; CANUTO, K. M.; BRITO, E. S. de; PESSOA, C. O.; NASCIMENTO, R. F.; ZOCOLO, G. J. Metabolic profile and cytotoxicity of non-polar extracts of pineapple leaves and chemometric analysis of different pineapple cultivars. Industrial Crops and Products, v. 124, p. 466-474, 2018.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 154. | | GUEDES, J. A. C.; ALVES FILHO, E. G.; RODRIGUES, T. H. S.; SILVA, M. F. S.; SOUZA, F. V. D.; SILVA, L. M. A. e; ALVES, R. E.; CANUTO, K. M.; BRITO, E. S. de; PESSOA, C. O.; NASCIMENTO, R. F.; ZOCOLO, G. J. Metabolic profile and cytotoxicity of non-polar extracts of pineapple leaves and chemometric analysis of different pineapple cultivars. I Industrial Crops and Products, v. 124, p. 466-474, 2018.| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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| 155. | | CASTRO, C. B. DE; LUZ, L. DOS R.; GUEDES, J. A. C.; PORTO, D. D.; SILVA, M. F. S.; SILVA, G. S. DA; RIBEIRO, P. R. V.; CANUTO, K. M.; BRITO, E. S. de; ZAMPIERI, D. DE S.; Ó, C. DO; ZOCOLO, G. J. Metabolomics-based discovery of biomarkers with cytotoxic potential in extracts of Myracrodruon urundeuva. Journal of the Brazilian Chemical Society, v. 31,n. 4, p. 775-787, 2020.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 156. | | CASTRO, C. B. DE; LUZ, L. DOS R.; GUEDES, J. A. C.; PORTO, D. D.; SILVA, M. F. S.; SILVA, G. S. DA; RIBEIRO, P. R. V.; CANUTO, K. M.; BRITO, E. S. de; ZAMPIERI, D. DE S.; PESSOA, C. do Ó.; ZOCOLO, G. J. Metabolomics-based discovery of biomarkers with cytotoxic potential in extracts of Myracrodruon urundeuva. Journal of the Brazilian Chemical Society, v. 31, n. p. 775-787, 2020.| Biblioteca(s): Embrapa Semiárido. |
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| 157. | | LEITE, E. L. L.; SOUZA, A. S. DE Q.; RIBEIRO, P. R. V.; PEREIRA, R. de C. A.; MARTINS, N. F.; FERREIRA, M. K. A.; MENEZES, J. E. S. A. DE; SANTOS, H. S. DOS; PESSOA, O. D. L.; CANUTO, K. M. Molecular Docking and GC/MS-Based Approach for Identification of Anxiolytic Alkaloids from Griffinia (Amaryllidaceae) Species in a Zebrafish Model. Chemistry Biodiversity, 21, e202302122, 2024.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 158. | | GUARNIZ, W. A. S.; CANUTO, K. M.; RIBEIRO, P. R. V.; LIMA, H. V. D.; MAGALHÃES, K. DO N.; SÁ, K. M.; NASCIMENTO, P. G. G. DO; SILVA, K. L.; SALES, G. W. P.; MONTEIRO, M. P.; NOGUEIRA, N. A. PINTO; BALOGUN, S. O.; BANDEIRA, M. A. M. Momordica charantia L. variety from Northeastern Brazil: analysis of antimicrobial activity and phytochemical components. Pharmacognosy Journal, Bengaluru, v. 11, n. 6, p. 1312-1324, Nov./Dec. 2019.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 159. | | MATOS, T. S.; SILVA, A. K. O.; QUINTELA, A. L.; PINTO, F. das C.; CANUTO, K. M.; BRAZ-FILHO, R.; FONSECA, M. J. da; LUNA-COSTA, A. M.; PAZ, I. A.; NASCIMENTO, N. R. F. do; SILVEIRA, E. R.; PESSOA, O. D. L. Neuroinhibitory meroterpenoid compounds from Cordia oncocalyx. Fitoterapia, v. 123, p. 65-72, 2017.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 160. | | GUEDES, J. A. C.; SANTIAGO, Y. G.; LUZ, L. dos R.; SILVA, M. F. S.; RAMIRES, C. M. C.; LIMA, M. A. C. de; OLIVEIRA, V. R. de; PESSOA. C. do Ó.; CANUTO, K. M.; BRITO, E. S. de; LIMA, M. F.; ALVES, R. E.; ZAMPIERI, D.; NASCIMENTO, R. F. do; ZOCOLO, G. J. Comparative analyses of metabolic fingerprint integrated with cytotoxic activity and in silico approaches of the leaves extract of Spondias mombin L. and Spondias tuberosa Arr. Cam. from Northeast, Brazil. Phytochemistry Letters, v. 40, p. 26-36, 2020.| Biblioteca(s): Embrapa Agroindústria Tropical; Embrapa Semiárido. |
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| Registros recuperados : 174 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agroindústria Tropical. Para informações adicionais entre em contato com cnpat.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Agroindústria Tropical; Embrapa Alimentos e Territórios. |
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Data corrente: |
02/01/2023 |
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Data da última atualização: |
29/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
B - 1 |
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Autoria: |
LIMA, L. F. DE; ANDRADE-PINHEIRO, J. C.; FREITAS, M. A.; SILVA, A. I. DA; FONSECA, V. J. A.; SILVA, T. G. DA; SILVA, J. C. P. DA; LIMA, R. H. DE; SALES, D. L.; NEVES, R. P.; BRITO, E. S. de; RIBEIRO, P. R. V.; CANUTO, K. M.; COUTINHO, H. D. M.; SIYADATPANAH, A.; KIM, B.; MORAIS-BRAGA, M. F. B. |
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Afiliação: |
LUCIENE FERREIRA DE LIMA, University Regional of Cariri; JACQUELINE COSMO ANDRADE-PINHEIRO, University Regional of Cariri; MARIA AUDILENE FREITAS, University Federal of Pernambuco; ADRIELY IDALINA DA SILVA, University Federal of Pernambuco; VICTOR JUNO ALENCAR FONSECA, University Regional of Cariri; TAÍS GUSMÃO DA SILVA, University Regional of Cariri; JOSEFA CAROLAINE PEREIRA DA SILVA, University Regional of Cariri; ROSILAINE HONORATO DE LIMA, University Regional of Cariri; DÉBORA LIMA SALES, University Regional of Cariri; REJANE PEREIRA NEVES, University Federal of Pernambuco; EDY SOUSA DE BRITO, CNAT; PAULO RICELI VASCONCELOS RIBEIRO, CNPAT; KIRLEY MARQUES CANUTO, CNPAT; HENRIQUE DOUGLAS MELO COUTINHO, University Regional of Cariri; ABOLGHASEM SIYADATPANAH, Birjand University of Medical Sciences; BONGLEE KIM, Kyung Hee University; MARIA FLAVIANA BEZERRA MORAIS-BRAGA, University Regional of Cariri. |
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Título: |
Anti-Candida properties of Gossypium hirsutum L.: enhancement of fungal growth, biofilm production and antifungal resistance. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Pharmaceutics, v. 14, n. 698, 2022. |
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Páginas: |
18 p. |
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DOI: |
https://doi.org/10.3390/pharmaceutics140406982022 |
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Idioma: |
Inglês |
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Conteúdo: |
(1) Background: Candida is a genus of yeasts with notable pathogenicity and significant ability to develop antimicrobial resistance. Gossypium hirsutum L., a medicinal plant that is traditionally used due to its antimicrobial properties, has demonstrated significant antifungal activity. Therefore, this study investigated the chemical composition and anti-Candida effects of aqueous (AELG) and hydroethanolic (HELG) extracts obtained from the leaves of this plant. (2) Methods: The extracts were chemically characterized by UPLC-QTOF-MS/MS, and their anti-Candida activities were investigated by analyzing cell viability, biofilm production, morphological transition, and enhancement of antifungal resistance. (3) Results: The UPLC-QTOF-MS/MS analysis revealed the presence of twenty-one compounds in both AELG and HELG, highlighting the predominance of flavonoids. The combination of the extracts with fluconazole significantly reduced its IC50 values against Candida albicans INCQS 40006, Candida tropicalis INCQS 40042, and C. tropicalis URM 4262 strains, indicating enhanced antifungal activity. About biofilm production, significant inhibition was observed only for the AELG-treated C. tropicalis URM 4262 strain in comparison with the untreated control. Accordingly, this extract showed more significant inhibitory effects on the morphological transition of the INCQS 40006 and URM 4387 strains of C. albicans (4) Conclusions: Gossypium hirsutum L. presents promising antifungal effects, that may be potentially linked to the combined activity of chemical constituents identified in its extracts. Menos(1) Background: Candida is a genus of yeasts with notable pathogenicity and significant ability to develop antimicrobial resistance. Gossypium hirsutum L., a medicinal plant that is traditionally used due to its antimicrobial properties, has demonstrated significant antifungal activity. Therefore, this study investigated the chemical composition and anti-Candida effects of aqueous (AELG) and hydroethanolic (HELG) extracts obtained from the leaves of this plant. (2) Methods: The extracts were chemically characterized by UPLC-QTOF-MS/MS, and their anti-Candida activities were investigated by analyzing cell viability, biofilm production, morphological transition, and enhancement of antifungal resistance. (3) Results: The UPLC-QTOF-MS/MS analysis revealed the presence of twenty-one compounds in both AELG and HELG, highlighting the predominance of flavonoids. The combination of the extracts with fluconazole significantly reduced its IC50 values against Candida albicans INCQS 40006, Candida tropicalis INCQS 40042, and C. tropicalis URM 4262 strains, indicating enhanced antifungal activity. About biofilm production, significant inhibition was observed only for the AELG-treated C. tropicalis URM 4262 strain in comparison with the untreated control. Accordingly, this extract showed more significant inhibitory effects on the morphological transition of the INCQS 40006 and URM 4387 strains of C. albicans (4) Conclusions: Gossypium hirsutum L. presents promising antifungal effects, that... Mostrar Tudo |
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Palavras-Chave: |
Antimicrobial resistance; Biofilm eradication; Erradicação do biofilme; Resistência antimicrobiana; UPLC-QTOF-MS/MS. |
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Thesagro: |
Gossypium Hirsutum; Malvaceae. |
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Categoria do assunto: |
--
W Química e Física |
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Marc: |
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001 2153889
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008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.3390/pharmaceutics140406982022$2DOI
100 1 $aLIMA, L. F. DE
245 $aAnti-Candida properties of Gossypium hirsutum L.$benhancement of fungal growth, biofilm production and antifungal resistance.$h[electronic resource]
260 $c2022
300 $a18 p.
520 $a(1) Background: Candida is a genus of yeasts with notable pathogenicity and significant ability to develop antimicrobial resistance. Gossypium hirsutum L., a medicinal plant that is traditionally used due to its antimicrobial properties, has demonstrated significant antifungal activity. Therefore, this study investigated the chemical composition and anti-Candida effects of aqueous (AELG) and hydroethanolic (HELG) extracts obtained from the leaves of this plant. (2) Methods: The extracts were chemically characterized by UPLC-QTOF-MS/MS, and their anti-Candida activities were investigated by analyzing cell viability, biofilm production, morphological transition, and enhancement of antifungal resistance. (3) Results: The UPLC-QTOF-MS/MS analysis revealed the presence of twenty-one compounds in both AELG and HELG, highlighting the predominance of flavonoids. The combination of the extracts with fluconazole significantly reduced its IC50 values against Candida albicans INCQS 40006, Candida tropicalis INCQS 40042, and C. tropicalis URM 4262 strains, indicating enhanced antifungal activity. About biofilm production, significant inhibition was observed only for the AELG-treated C. tropicalis URM 4262 strain in comparison with the untreated control. Accordingly, this extract showed more significant inhibitory effects on the morphological transition of the INCQS 40006 and URM 4387 strains of C. albicans (4) Conclusions: Gossypium hirsutum L. presents promising antifungal effects, that may be potentially linked to the combined activity of chemical constituents identified in its extracts.
650 $aGossypium Hirsutum
650 $aMalvaceae
653 $aAntimicrobial resistance
653 $aBiofilm eradication
653 $aErradicação do biofilme
653 $aResistência antimicrobiana
653 $aUPLC-QTOF-MS/MS
700 1 $aANDRADE-PINHEIRO, J. C.
700 1 $aFREITAS, M. A.
700 1 $aSILVA, A. I. DA
700 1 $aFONSECA, V. J. A.
700 1 $aSILVA, T. G. DA
700 1 $aSILVA, J. C. P. DA
700 1 $aLIMA, R. H. DE
700 1 $aSALES, D. L.
700 1 $aNEVES, R. P.
700 1 $aBRITO, E. S. de
700 1 $aRIBEIRO, P. R. V.
700 1 $aCANUTO, K. M.
700 1 $aCOUTINHO, H. D. M.
700 1 $aSIYADATPANAH, A.
700 1 $aKIM, B.
700 1 $aMORAIS-BRAGA, M. F. B.
773 $tPharmaceutics$gv. 14, n. 698, 2022.
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