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| Registros recuperados : 148 | |
| 81. |  | BIONDO, N.; SCHAEFER, R.; GAVA, D.; CANTAO, M. E.; SILVEIRA, S.; MORES, M. A. Z.; ZANELLA, J. R. C.; BARCELLOS, D. E. S. N. de. Genomic analysis of influenza A virus from captive wild boars in Brazil reveals a human-like H1N2 influenza virus. Veterinary Microbiology, Amsterdam, NL, v. 168, n. 1, p. 34-40, 2014.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 82. | | BIONDO, N.; SCHAEFER, R.; GAVA, D.; CANTAO, M. E.; SILVEIRA, S.; MORES, M. A. Z.; ZANELLA, J. R. C.; BARCELLOS, D. E. S. N. Genomic analysis of influenza a virus from captive wild boars in Brazil reveals a human-like H1N2 influenza virus. In: INTERNATIONAL PIG VETERINARY SOCIETY CONGRESS, 23., Cancun. Proceedings... León, México: IPVS, 2014. p. 319| Biblioteca(s): Embrapa Suínos e Aves. |
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| 83. | | ZANELLA, R.; PEIXOTO, J. de O.; CARDOSO, F. F.; CARDOSO, L. L.; BIEGELMEYER, P.; CANTAO, M. E.; OTAVIANO, A.; FREITAS, M. S.; CAETANO, A. R.; LEDUR, M. C. Genetic diversity analysis of two commercial breeds of pigs using genomic and pedigree data. Genetics Selection Evolution, v. 48, n. 24, 30 Mar. 2016.| Biblioteca(s): Embrapa Pecuária Sul; Embrapa Recursos Genéticos e Biotecnologia; Embrapa Suínos e Aves. |
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| 84. | | ZANELLA, R.; GAVA, D.; PEIXOTO, J. de O.; SCHAEFER, R.; ZANELLA, J. R. C.; BIONDO, N.; SILVA, M. V. G. B.; CANTAO, M. E.; LEDUR, M. C. Genetic markers associated with influenza vaccination efficacy in swine. In: INTERNATIONAL SYMPOSIUM ON EMERGING AND RE-EMERGING PIG DISEASES, 7., 2015, Kyoto. Proceedings... Kyoto: Science Council of Japan; JSVS; JPVS; JASV, 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 86. | | ZANELLA, R.; IBELLI, A. M. G.; PEIXOTO, J. de O.; CANTAO, M. E.; SILVA, M. V. G. B.; GIACHETTO, P. F.; FREITAS, M.; LOPES, J.; LEDUR, M. C. Genetic associations of farrowing length in two maternal lines of pigs. In: WORLD CONGRESS OF GENETICS APPLIED TO LIVESTOCK PRODUCTION, 10., 2014, Vancouver. Proceedings... Vancouver: WCGALP: American Society of Animal Science, 2014.| Biblioteca(s): Embrapa Gado de Leite; Embrapa Suínos e Aves. |
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| 87. | | GOLDONI, I.; IBELLI, A. M. G.; FERNANDES, L. T.; PEIXOTO, J. de O.; HUL, L. M.; CANTAO, M. E.; GOUVEIA, J. J. de S.; LEDUR, M. C. Comprehensive analyses of bone and cartilage transcriptomes evince ion transport, inflammation and cartilage development-related genes involved in chickens femoral head separation. Animals, v. 12, n. 788, 2022.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 88. | | MARCHESI, J. A. P.; IBELLI, A. M. G.; CANTAO, M. E.; ZANELLA, R.; SETTLES, M. L.; PEIXOTO, J. de O.; COUTINHO, L. L.; LEDUR, M. C. Whole transcriptome analysis of pectoralis major muscle reveals differences in calcium signaling pathway between white striping affected and unaffected broilers. In: CONGRESSO BRASILEIRO DE GENÉTICA, 61., 2015, Águas de Lindóia. Resumos... Ribeirão Preto: Sociedade Brasileira de Genética, 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 89. | | FORNARI, M. B.; ZANELLA, R.; IBELLI, A. M. G.; FERNANDES, L. T.; CANTAO, M. E.; SOCCOL, V. T.; LEDUR, M. C.; PEIXOTO, J. de O. Unraveling the associations of osteoprotegerin gene with production traits in a paternal broiler line. SpringerPlus, v. 3, n. 682, 2014.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 90. | | PETRY, B.; ZANELLA, R.; IBELLI, A. M. G.; FORNARI, M. B.; PANDOLFI, J. R. C.; CANTAO, M. E.; COUTINHO, L. L.; PEIXOTO, J. de O.; LEDUR, M. C. Unraveling the associations of SOST gene with production traits in an F2 Chicken Resource Population. In: CONGRESSO BRASILEIRO DE GENÉTICA, 59., 2013, Águas de Lindóia. Resumos... Ribeirão Preto: SBG, 2013. p. 152.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 91. | | ZANELLA, R.; GAVA, D.; PEIXOTO, J. de O.; SCHAEFER, R.; CIACCI-ZANELLA, J. R.; BIONDO, N.; SILVA, M. V. G. B.; CANTÃO, M. E.; LEDUR, M. C. Unravelling the genetic components involved in the immune response of pigs vaccinated against influenza virus. Virus Research, v. 210, p. 327-336, 2015.| Biblioteca(s): Embrapa Gado de Leite. |
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| 92. | | ZANELLA, R.; GAVA, D.; PEIXOTO, J. de O.; SCHAEFER, R.; ZANELLA, J. R. C.; BIONDO, N.; SILVA, M. V. G. B.; CANTAO, M. E.; LEDUR, M. C. Unravelling the genetic components involved in the immune response of pigs vaccinated against influenza virus. Virus Research, v. 210, p. 327-336, 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 93. | | ZANELLA, R.; IBELLI, A. M. G.; CANTAO, M. E.; PEIXOTO, J. de O.; PANDOLFI, J. R. C.; COUTINHO, L. L.; LEDUR, M. C. Unrevealing the genetic pathways involved with bone integrity traits in poultry. In: INTERNATIONAL SYMPOSIUM ON ANIMAL FUNCTIONAL GENOMICS, 5., 2013, Guarujá. Programme and abstract book... [S.l.: s.n.], 2013. p. 31. ISAFG 2013. AB. 25.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 94. | | MARCHESI, J. A. P.; ONO, R. K.; CANTAO, M. E.; IBELLI, A. M. G.; PEIXOTO, J. de O.; MOREIRA, G. C. M.; GODOY, T. F.; COUTINHO, L. L.; MUNARI, D. P.; LEDUR, M. C. Exploring the genetic architecture of feed efficiency traits in chickens. Scientific Reports, v. 11, n. 4622, 2021.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 95. | | SALMÓRIA, L. A.; IBELLI, A. M. G.; TAVERNARI, F. de C.; PEIXOTO, J. de O.; MARCELINO, D. E. P.; DAL PIZZOL, M. S.; CANTAO, M. E.; LEDUR, M. C. Expressão diferencial de genes relacionados ao metabolismo de cálcio e fósforo em poedeiras com diferentes níveis de desempenho. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL ON-LINE, 14., 2021. Anais.... Chapecó: UDESC: Concórdia: Embrapa Suínos e Aves, 2022.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 96. | | PEIXOTO, J. de O.; IBELLI, A. M. G.; CANTAO, M. E.; ZANELLA, R.; JAENISCH, F. R. F.; GIACHETTO, P. F.; SETTLES, M. L.; PANDOLFI, J. R. C.; COUTINHO, L. L.; LEDUR, M. C. Expressão gênica diferencial envolvida com condronecrose bacteriana com osteomielite em frangos de corte com 35 dias de idade. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 52., 2015, Belo Horizonte. Zootecnia: otimizando recursos e potencialidades: anais. Brasília, DF: Sociedade Brasileira de Zootecnia, 2015.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Suínos e Aves. |
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| 97. | | TEIXEIRA, S. A.; IBELLI, A. M. G.; CANTAO, M. E.; OLIVEIRA, H. C. de; LEDUR, M. C.; PEIXOTO, J. de O.; MARQUES, D. B. D.; COSTA, K. A.; COUTINHO, L. L.; GUIMARÃES, S. E. F. Sex determination using RNA-sequencing analyses in early prenatal pig development. Genes, v. 10, n. 1010, 2019.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 98. | | PACCHION, R. G.; CARVALHO, F. M.; THOMPSON, C. E.; FAUSTINO, A. L. F.; NICOLINI, F.; PEREIRA, T. S.; SILVA, R. C. B.; CANTAO, M. E.; GERBER, A.; VASCONCELOS, A. T. R.; AGNEZ-LIMA, L. F. Taxonomic and functional profiles of soil samples from Atlantic Forest and caatinga biomes in northeastern Brazil MicrobiologyOpen, Brussels, v. 3, n. 3, p. 299-315, 2014. DOI: 10.1002/mbo3.169.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 99. | | SAVOLDI, I. R.; IBELLI, A. M. G.; CANTAO, M. E.; PEIXOTO, J. de O.; MORES, M. A. Z.; LAGOS, E. B.; LOPES, J. S.; ZANELLA, R.; LEDUR, M. C. A joint analysis using exome and transcriptome data identifiescandidate polymorphisms and genes involved with umbilical hernia in pigs. BMC Genomics, v. 22, n. 818, 2021.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 100. | | ZANELLA, J. R. C.; SCHAEFER, R.; GAVA, D.; KLEIN, C. S.; CANTAO, M. E.; SILVA, V. S.; MORES, M. A. Z.; SILVA, M. C. da; MORES, N.; RECH, R. R.; CARON, L. Influenza A virus infection on swine in Brazil. O Biológico, São Paulo, v. 75, p. 32, 2013. Suplemento 2, ref. 30. Edição dos Resumos do 3 Encontro Nacional de Defesa Sanitária Animal, Foz de Iguaçu, dez. 2013.| Biblioteca(s): Embrapa Suínos e Aves. |
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| Registros recuperados : 148 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Suínos e Aves. Para informações adicionais entre em contato com cnpsa.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
16/11/2021 |
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Data da última atualização: |
16/11/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
SAVOLDI, I. R.; IBELLI, A. M. G.; CANTAO, M. E.; PEIXOTO, J. de O.; MORES, M. A. Z.; LAGOS, E. B.; LOPES, J. S.; ZANELLA, R.; LEDUR, M. C. |
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Afiliação: |
IGOR RICARDO SAVOLDI, UDESC/Chapecó; ADRIANA MERCIA GUARATINI IBELLI, CNPSA; MAURICIO EGIDIO CANTAO, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; MARCOS ANTONIO ZANELLA MORES, CNPSA; ESSAMAI BRIZOLA LAGOS, UEPG; JADER SILVA LOPES, BRF/Curitiba; RICARDO ZANELLA, UPF; MONICA CORREA LEDUR, CNPSA. |
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Título: |
A joint analysis using exome and transcriptome data identifiescandidate polymorphisms and genes involved with umbilical hernia in pigs. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
BMC Genomics, v. 22, n. 818, 2021. |
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DOI: |
https://doi.org/10.1186/s12864-021-08138-4 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Background: Umbilical Hernia (UH) is characterized by the passage of part of the intestine through the umbilical canal forming the herniary sac. There are several potential causes that can lead to the umbilical hernia such as bacterial infections, management conditions and genetic factors. Since the genetic components involved with UH are poorly understood, this study aimed to identify polymorphisms and genes associated with the manifestation of umbilical hernia in pigs using exome and transcriptome sequencing in a case and control design. Results: In the exome sequencing, 119 variants located in 58 genes were identified differing between normal and UH-affected pigs, and in the umbilical ring transcriptome, 46 variants were identified, located in 27 genes. Comparing the two methodologies, we obtained 34 concordant variants between the exome and transcriptome analyses, which were located in 17 genes, distributed in 64 biological processes (BP). Among the BP involved with UH it is possible to highlight cell adhesion, cell junction regulation, embryonic morphogenesis, ion transport, muscle contraction, within others. Conclusions: We have generated the first exome sequencing related to normal and umbilical hernia-affected pigs, which allowed us to identify several variants possibly involved with this disorder. Many of those variants present in the DNA were confirmed with the RNA-Seq results. The combination of both exome and transcriptome sequencing approaches allowed us to better understand the complex molecular mechanisms underlying UH in pigs and possibly in other mammals, including humans. Some variants found in genes and other regulatory regions are highlighted as strong candidates to the development of UH in pigs and should be further investigated. MenosAbstract: Background: Umbilical Hernia (UH) is characterized by the passage of part of the intestine through the umbilical canal forming the herniary sac. There are several potential causes that can lead to the umbilical hernia such as bacterial infections, management conditions and genetic factors. Since the genetic components involved with UH are poorly understood, this study aimed to identify polymorphisms and genes associated with the manifestation of umbilical hernia in pigs using exome and transcriptome sequencing in a case and control design. Results: In the exome sequencing, 119 variants located in 58 genes were identified differing between normal and UH-affected pigs, and in the umbilical ring transcriptome, 46 variants were identified, located in 27 genes. Comparing the two methodologies, we obtained 34 concordant variants between the exome and transcriptome analyses, which were located in 17 genes, distributed in 64 biological processes (BP). Among the BP involved with UH it is possible to highlight cell adhesion, cell junction regulation, embryonic morphogenesis, ion transport, muscle contraction, within others. Conclusions: We have generated the first exome sequencing related to normal and umbilical hernia-affected pigs, which allowed us to identify several variants possibly involved with this disorder. Many of those variants present in the DNA were confirmed with the RNA-Seq results. The combination of both exome and transcriptome sequencing approaches allowed ... Mostrar Tudo |
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Palavras-Chave: |
Defeitos congênitos; Hérnia umbilical; RNA sequencing; RNA-Seq; Sequenciamento de exoma; SNP. |
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Thesagro: |
Abacate; Genética Animal; Suíno. |
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Thesaurus NAL: |
Animal genetics; Sequence analysis; Single nucleotide polymorphism; Swine. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02916naa a2200385 a 4500
001 2136149
005 2021-11-16
008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1186/s12864-021-08138-4$2DOI
100 1 $aSAVOLDI, I. R.
245 $aA joint analysis using exome and transcriptome data identifiescandidate polymorphisms and genes involved with umbilical hernia in pigs.$h[electronic resource]
260 $c2021
520 $aAbstract: Background: Umbilical Hernia (UH) is characterized by the passage of part of the intestine through the umbilical canal forming the herniary sac. There are several potential causes that can lead to the umbilical hernia such as bacterial infections, management conditions and genetic factors. Since the genetic components involved with UH are poorly understood, this study aimed to identify polymorphisms and genes associated with the manifestation of umbilical hernia in pigs using exome and transcriptome sequencing in a case and control design. Results: In the exome sequencing, 119 variants located in 58 genes were identified differing between normal and UH-affected pigs, and in the umbilical ring transcriptome, 46 variants were identified, located in 27 genes. Comparing the two methodologies, we obtained 34 concordant variants between the exome and transcriptome analyses, which were located in 17 genes, distributed in 64 biological processes (BP). Among the BP involved with UH it is possible to highlight cell adhesion, cell junction regulation, embryonic morphogenesis, ion transport, muscle contraction, within others. Conclusions: We have generated the first exome sequencing related to normal and umbilical hernia-affected pigs, which allowed us to identify several variants possibly involved with this disorder. Many of those variants present in the DNA were confirmed with the RNA-Seq results. The combination of both exome and transcriptome sequencing approaches allowed us to better understand the complex molecular mechanisms underlying UH in pigs and possibly in other mammals, including humans. Some variants found in genes and other regulatory regions are highlighted as strong candidates to the development of UH in pigs and should be further investigated.
650 $aAnimal genetics
650 $aSequence analysis
650 $aSingle nucleotide polymorphism
650 $aSwine
650 $aAbacate
650 $aGenética Animal
650 $aSuíno
653 $aDefeitos congênitos
653 $aHérnia umbilical
653 $aRNA sequencing
653 $aRNA-Seq
653 $aSequenciamento de exoma
653 $aSNP
700 1 $aIBELLI, A. M. G.
700 1 $aCANTAO, M. E.
700 1 $aPEIXOTO, J. de O.
700 1 $aMORES, M. A. Z.
700 1 $aLAGOS, E. B.
700 1 $aLOPES, J. S.
700 1 $aZANELLA, R.
700 1 $aLEDUR, M. C.
773 $tBMC Genomics$gv. 22, n. 818, 2021.
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