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Registro Completo |
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
21/08/2023 |
Data da última atualização: |
21/08/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
OTTO, P. I.; GUIMARÃES, S. E. F.; CALUS, M. P. L.; VANDENPLAS, J.; MACHADO, M. A.; PANETTO, J. C. do C.; SILVA, M. V. G. B. |
Afiliação: |
PAMELA I. OTTO, Universidade Federal de Viçosa; SIMONE E. F. GUIMARÃES, Universidade Federal de Viçosa; MARIO P. L. CALUS, Wageningen University & Research; JEREMIE VANDENPLAS, Wageningen University & Research; MARCO ANTONIO MACHADO, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL. |
Título: |
Single-step genome-wide association studies (GWAS) and post-GWAS analyses to identify genomic regions and candidate genes for milk yield in Brazilian Girolando cattle. |
Ano de publicação: |
2020 |
Fonte/Imprenta: |
Journal of Dairy Science, v. 103, n. 11, p. 10347-10360, 2020. |
DOI: |
https://doi.org/10.3168/jds.2019-17890 |
Idioma: |
Inglês |
Conteúdo: |
Milk production is economically important to the Brazilian agribusiness, and the majority of the country's milk production derives from Girolando (Gir × Holstein) cows. This study aimed to identify quantitative trait loci (QTL) and candidate genes associated with 305-d milk yield (305MY) in Girolando cattle. In addition, we investigated the SNP-specific variances for Holstein and Gir breeds of origin within the sequence of candidate genes. A single-step genomic BLUP procedure was used to identify QTL associated with 305MY, and the most likely candidate genes were identified through follow-up analyses. Genomic breeding values specific for Holstein and Gir were estimated in the Girolando animals using a model that uses breed-specific partial relationship matrices, which were converted to breed of origin SNP effects. Differences between breed of origin were evaluated by comparing estimated SNP variances between breeds. From 10 genome regions explaining most additive genetic variance for 305MY in Girolando cattle, 7 candidate genes were identified on chromosomes 1, 4, 6, and 26. Within the sequence of these 7 candidate genes, Gir breed of origin SNP alleles showed the highest genetic variance. These results indicated QTL regions that could be further explored in genomic selection panels and which may also help in understanding the gene mechanisms involved in milk production in the Girolando breed. |
Thesagro: |
Gado Gir; Gado Leiteiro; Gene; Produção Leiteira. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
Marc: |
LEADER 02266naa a2200253 a 4500 001 2156012 005 2023-08-21 008 2020 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.3168/jds.2019-17890$2DOI 100 1 $aOTTO, P. I. 245 $aSingle-step genome-wide association studies (GWAS) and post-GWAS analyses to identify genomic regions and candidate genes for milk yield in Brazilian Girolando cattle.$h[electronic resource] 260 $c2020 520 $aMilk production is economically important to the Brazilian agribusiness, and the majority of the country's milk production derives from Girolando (Gir × Holstein) cows. This study aimed to identify quantitative trait loci (QTL) and candidate genes associated with 305-d milk yield (305MY) in Girolando cattle. In addition, we investigated the SNP-specific variances for Holstein and Gir breeds of origin within the sequence of candidate genes. A single-step genomic BLUP procedure was used to identify QTL associated with 305MY, and the most likely candidate genes were identified through follow-up analyses. Genomic breeding values specific for Holstein and Gir were estimated in the Girolando animals using a model that uses breed-specific partial relationship matrices, which were converted to breed of origin SNP effects. Differences between breed of origin were evaluated by comparing estimated SNP variances between breeds. From 10 genome regions explaining most additive genetic variance for 305MY in Girolando cattle, 7 candidate genes were identified on chromosomes 1, 4, 6, and 26. Within the sequence of these 7 candidate genes, Gir breed of origin SNP alleles showed the highest genetic variance. These results indicated QTL regions that could be further explored in genomic selection panels and which may also help in understanding the gene mechanisms involved in milk production in the Girolando breed. 650 $aGado Gir 650 $aGado Leiteiro 650 $aGene 650 $aProdução Leiteira 700 1 $aGUIMARÃES, S. E. F. 700 1 $aCALUS, M. P. L. 700 1 $aVANDENPLAS, J. 700 1 $aMACHADO, M. A. 700 1 $aPANETTO, J. C. do C. 700 1 $aSILVA, M. V. G. B. 773 $tJournal of Dairy Science$gv. 103, n. 11, p. 10347-10360, 2020.
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Embrapa Gado de Leite (CNPGL) |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
06/07/2017 |
Data da última atualização: |
30/01/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
GUIMARÃES, J. de L. B; BRITO, M. A. V. P. e; LANGE, C. C.; SILVA, M. R.; RIBEIRO, J. B.; MENDONCA, L. C.; MENDONÇA, J. F. M.; SOUZA, G. N. de. |
Afiliação: |
JULIANA DE L. B. GUIMARÃES, FAPEMIG; MARIA APARECIDA V PAIVA E BRITO, CNPGL; CARLA CHRISTINE LANGE, CNPGL; MARCIO ROBERTO SILVA, CNPGL; JOAO BATISTA RIBEIRO, CNPGL; LETICIA CALDAS MENDONCA, CNPGL; JULIANA FRANÇA MONTEIRO DE MENDONÇA, UFJF; GUILHERME NUNES DE SOUZA, CNPGL. |
Título: |
Estimate of the economic impact of mastitis: A case study in a Holstein dairy herd under tropical conditions. |
Ano de publicação: |
2017 |
Fonte/Imprenta: |
Preventive Veterinary Medicine, v. 142, p. 46-50, 2017. |
Idioma: |
Inglês |
Conteúdo: |
The aim of this study was to estimate the economic impact of mastitis at the herd level and the weight (percent) of the components of this impact in a Holstein dairy herd under tropical conditions. Three estimates of the economic impact of mastitis were performed. In estimates 1 and 2 the real production and economic indices from February 2011 to January 2012 were considered. In the estimate 1, indices for mastitis classified as ideal were considered, whereas in the estimate 2, the mastitis indices used were those recorded at the farm and at Holstein Cattle Association of Minas Gerais State database (real indices). Ideal mastitis indices were bulk milk somatic cell counts less than 250,000 cells/mL, incidence of clinical mastitis less than 25 cases/100 cows/year, number of culls due to udder health problems less than 5% and the percentage of cows with somatic cell counts greater than 200,000 cells/mL less than 20%. Considering the ideal indices of mastitis, the economic impact was US$19,132.35. The three main components of the economic impact were culling cows (39.4%) and the reduction in milk production due to subclinical and clinical mastitis (32.3% and 18.2%, respectively). Estimate 2 using real mastitis indices showed an economic impact of US$61,623.13 and the reduction in milk production due to mastitis (77.7%) and milk disposal (14.0%) were the most relevant components. The real impact of culling cows was approximately 16 times less than the weight that was considered ideal, indicating that this procedure could have been more frequently adopted. The reduction in milk production was 27.2% higher than the reduction in Estimate 1, indicating a need to control and prevent mastitis. The estimate 3 considered the same indices as estimate 2, but for the period from February 2012 to January 2013. Its economic impact was US$91,552.69. During this period, 161 treatments of cows with an intramammary antibiotic were performed to eliminate Streptococcus agalactiae, and eight cows chronically infected with Staphylococcus aureus were culled. The reduction in milk production due to mastitis was the main component of the economic impact (54.9%). The culling of cows with chronic infection was associated with an increase in the economic impact of mastitis and a reduction in the average productivity per cow. At the herd level reduction in milk production was the component that presented the largest weight in the economic impact of the disease MenosThe aim of this study was to estimate the economic impact of mastitis at the herd level and the weight (percent) of the components of this impact in a Holstein dairy herd under tropical conditions. Three estimates of the economic impact of mastitis were performed. In estimates 1 and 2 the real production and economic indices from February 2011 to January 2012 were considered. In the estimate 1, indices for mastitis classified as ideal were considered, whereas in the estimate 2, the mastitis indices used were those recorded at the farm and at Holstein Cattle Association of Minas Gerais State database (real indices). Ideal mastitis indices were bulk milk somatic cell counts less than 250,000 cells/mL, incidence of clinical mastitis less than 25 cases/100 cows/year, number of culls due to udder health problems less than 5% and the percentage of cows with somatic cell counts greater than 200,000 cells/mL less than 20%. Considering the ideal indices of mastitis, the economic impact was US$19,132.35. The three main components of the economic impact were culling cows (39.4%) and the reduction in milk production due to subclinical and clinical mastitis (32.3% and 18.2%, respectively). Estimate 2 using real mastitis indices showed an economic impact of US$61,623.13 and the reduction in milk production due to mastitis (77.7%) and milk disposal (14.0%) were the most relevant components. The real impact of culling cows was approximately 16 times less than the weight that was considered ... Mostrar Tudo |
Palavras-Chave: |
Culling cows; Milk disposal; Reduction of milk production. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
Marc: |
LEADER 03222naa a2200241 a 4500 001 2072116 005 2023-01-30 008 2017 bl uuuu u00u1 u #d 100 1 $aGUIMARÃES, J. de L. B 245 $aEstimate of the economic impact of mastitis$bA case study in a Holstein dairy herd under tropical conditions.$h[electronic resource] 260 $c2017 520 $aThe aim of this study was to estimate the economic impact of mastitis at the herd level and the weight (percent) of the components of this impact in a Holstein dairy herd under tropical conditions. Three estimates of the economic impact of mastitis were performed. In estimates 1 and 2 the real production and economic indices from February 2011 to January 2012 were considered. In the estimate 1, indices for mastitis classified as ideal were considered, whereas in the estimate 2, the mastitis indices used were those recorded at the farm and at Holstein Cattle Association of Minas Gerais State database (real indices). Ideal mastitis indices were bulk milk somatic cell counts less than 250,000 cells/mL, incidence of clinical mastitis less than 25 cases/100 cows/year, number of culls due to udder health problems less than 5% and the percentage of cows with somatic cell counts greater than 200,000 cells/mL less than 20%. Considering the ideal indices of mastitis, the economic impact was US$19,132.35. The three main components of the economic impact were culling cows (39.4%) and the reduction in milk production due to subclinical and clinical mastitis (32.3% and 18.2%, respectively). Estimate 2 using real mastitis indices showed an economic impact of US$61,623.13 and the reduction in milk production due to mastitis (77.7%) and milk disposal (14.0%) were the most relevant components. The real impact of culling cows was approximately 16 times less than the weight that was considered ideal, indicating that this procedure could have been more frequently adopted. The reduction in milk production was 27.2% higher than the reduction in Estimate 1, indicating a need to control and prevent mastitis. The estimate 3 considered the same indices as estimate 2, but for the period from February 2012 to January 2013. Its economic impact was US$91,552.69. During this period, 161 treatments of cows with an intramammary antibiotic were performed to eliminate Streptococcus agalactiae, and eight cows chronically infected with Staphylococcus aureus were culled. The reduction in milk production due to mastitis was the main component of the economic impact (54.9%). The culling of cows with chronic infection was associated with an increase in the economic impact of mastitis and a reduction in the average productivity per cow. At the herd level reduction in milk production was the component that presented the largest weight in the economic impact of the disease 653 $aCulling cows 653 $aMilk disposal 653 $aReduction of milk production 700 1 $aBRITO, M. A. V. P. e 700 1 $aLANGE, C. C. 700 1 $aSILVA, M. R. 700 1 $aRIBEIRO, J. B. 700 1 $aMENDONCA, L. C. 700 1 $aMENDONÇA, J. F. M. 700 1 $aSOUZA, G. N. de 773 $tPreventive Veterinary Medicine$gv. 142, p. 46-50, 2017.
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