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| Acesso ao texto completo restrito à biblioteca da Embrapa Solos. Para informações adicionais entre em contato com cnps.biblioteca@embrapa.br. |
Registro Completo |
Biblioteca(s): |
Embrapa Solos. |
Data corrente: |
25/08/2016 |
Data da última atualização: |
25/08/2016 |
Autoria: |
AMARAL, A. J. do. |
Afiliação: |
ANDRE JULIO DO AMARAL, CNPS. |
Título: |
Erosão hídrica do solo no sistema de sucessão de culturas soja e trigo: fator C modelo USLE para soja e trigo. |
Ano de publicação: |
2015 |
Fonte/Imprenta: |
Saarbrücken: Novas Edições Acadêmicas, 2015. |
Páginas: |
97 p. |
ISBN: |
978-613-0-16945-9 |
Idioma: |
Português |
Palavras-Chave: |
Erosividade da chuva; Fator C da USLE; Razão de perda de solo. |
Thesagro: |
Erosão Hídrica. |
Categoria do assunto: |
P Recursos Naturais, Ciências Ambientais e da Terra |
Marc: |
LEADER 00570nam a2200169 a 4500 001 2051714 005 2016-08-25 008 2015 bl uuuu 00u1 u #d 020 $a978-613-0-16945-9 100 1 $aAMARAL, A. J. do 245 $aErosão hídrica do solo no sistema de sucessão de culturas soja e trigo$bfator C modelo USLE para soja e trigo.$h[electronic resource] 260 $aSaarbrücken: Novas Edições Acadêmicas$c2015 300 $a97 p. 650 $aErosão Hídrica 653 $aErosividade da chuva 653 $aFator C da USLE 653 $aRazão de perda de solo
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Registro Completo
Biblioteca(s): |
Embrapa Agroindústria Tropical; Embrapa Gado de Leite; Embrapa Instrumentação; Embrapa Pecuária Sudeste. |
Data corrente: |
25/01/2024 |
Data da última atualização: |
11/04/2024 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
ANHOLETO, L. A.; BRANCAGLION, G. A.; SANTOS, D. M. DOS; KAPRITCHKOFF, R. T. I.; CASTRO, K. N. de C.; CANUTO, K. M.; RODRIGUES, R. A. F.; CORREA, D. S.; CHAGAS, A. C. de S.; PASTRE, J. C. |
Afiliação: |
LUIS ADRIANO ANHOLETO; GUILHERME ANDRADE BRANCAGLION, UNIVERSIDADE DE CAMPINAS; DANILO MARTINS DOS SANTOS; RAFAELA TAMI IKEDA KAPRITCHKOFF, UNIVERSIDADE DE SÃO PAULO; KARINA NEOOB DE CARVALHO CASTRO, CNPGL; KIRLEY MARQUES CANUTO, CNPAT; RODNEY ALEXANDRE FERREIRA RODRIGUES, UNIVERSIDADE DE CAMPINAS; DANIEL SOUZA CORREA, CNPDIA; ANA CAROLINA DE SOUZA CHAGAS, CPPSE; JULIO CEZAR PASTRE, UNIVERSIDADE DE CAMPINAS. |
Título: |
Acaricidal activity of synthetic spilanthol derivative against ticks of medical and veterinary importance. |
Ano de publicação: |
2024 |
Fonte/Imprenta: |
Veterinary Parasitology, v. 327, Apr. 2024, 110137. |
Páginas: |
9 p. |
DOI: |
10.1016/j.vetpar.2024.110137 |
Idioma: |
Inglês |
Conteúdo: |
The ANESPSAT, a synthetic spilanthol derivative, and its nanoformulation were evaluated against Rhipicephalus microplus and Amblyomma sculptum ticks. ANESPSAT activity was compared with spilanthol and derivatives (ANESPE and others). The compound was synthesized in a gram-scale by a 2-step process, comprising a direct ester amidation and a Horner-Wadsworth- Emmons reaction. The nanoemulsions were produced by coarse homogenization followed by high-energy ultrasonication, in which hydrodynamic diameter, polydispersity index, and zeta potential remained stable. The spilanthol-eugenol hybrid derivatives did not show significant acaricidal activity. ANESPE killed 83% of the R. microplus larvae at 30 mg.mL−1, while ANESPSAT killed 97% at 0.5 mg.mL−1, showing to be the most active compound. Spilanthol and ANESPSAT had similar high mortality rates for tick larvae, with LC50 values of 0.10 and 0.14 mg.mL−1 for R. microplus larvae, and 0.04 and 0.48 mg.mL−1 for A. sculptum larvae, respectively. The efficacy of spilanthol was lower against R. microplus engorged females when compared with ANESPSAT, which was highly effective (>98%) against R. microplus engorged females. The nanoemulsion with ANESPSAT was effective against tick females, preventing egg laying and achieving 100% efficacy at 2.5 mg.mL−1. Spilanthol had only 59% efficacy at 10 mg.mL−1. The results suggest that ANESPSAT, a natural product derivative, could be used in novel formulations for tick management that might be safer and environmentally friendly. MenosThe ANESPSAT, a synthetic spilanthol derivative, and its nanoformulation were evaluated against Rhipicephalus microplus and Amblyomma sculptum ticks. ANESPSAT activity was compared with spilanthol and derivatives (ANESPE and others). The compound was synthesized in a gram-scale by a 2-step process, comprising a direct ester amidation and a Horner-Wadsworth- Emmons reaction. The nanoemulsions were produced by coarse homogenization followed by high-energy ultrasonication, in which hydrodynamic diameter, polydispersity index, and zeta potential remained stable. The spilanthol-eugenol hybrid derivatives did not show significant acaricidal activity. ANESPE killed 83% of the R. microplus larvae at 30 mg.mL−1, while ANESPSAT killed 97% at 0.5 mg.mL−1, showing to be the most active compound. Spilanthol and ANESPSAT had similar high mortality rates for tick larvae, with LC50 values of 0.10 and 0.14 mg.mL−1 for R. microplus larvae, and 0.04 and 0.48 mg.mL−1 for A. sculptum larvae, respectively. The efficacy of spilanthol was lower against R. microplus engorged females when compared with ANESPSAT, which was highly effective (>98%) against R. microplus engorged females. The nanoemulsion with ANESPSAT was effective against tick females, preventing egg laying and achieving 100% efficacy at 2.5 mg.mL−1. Spilanthol had only 59% efficacy at 10 mg.mL−1. The results suggest that ANESPSAT, a natural product derivative, could be used in novel formulations for tick management that might be safer ... Mostrar Tudo |
Palavras-Chave: |
Acmella oleracea; Bovine parasite sadness; Brazilian Spotted Fever; Cattle tick; Control; Nanoformulation; Spilanthol. |
Thesagro: |
Bovino; Carrapato. |
Thesaurus NAL: |
Rickettsia rickettsii. |
Categoria do assunto: |
H Saúde e Patologia |
Marc: |
LEADER 02636naa a2200373 a 4500 001 2161314 005 2024-04-11 008 2024 bl uuuu u00u1 u #d 024 7 $a10.1016/j.vetpar.2024.110137$2DOI 100 1 $aANHOLETO, L. A. 245 $aAcaricidal activity of synthetic spilanthol derivative against ticks of medical and veterinary importance.$h[electronic resource] 260 $c2024 300 $a9 p. 520 $aThe ANESPSAT, a synthetic spilanthol derivative, and its nanoformulation were evaluated against Rhipicephalus microplus and Amblyomma sculptum ticks. ANESPSAT activity was compared with spilanthol and derivatives (ANESPE and others). The compound was synthesized in a gram-scale by a 2-step process, comprising a direct ester amidation and a Horner-Wadsworth- Emmons reaction. The nanoemulsions were produced by coarse homogenization followed by high-energy ultrasonication, in which hydrodynamic diameter, polydispersity index, and zeta potential remained stable. The spilanthol-eugenol hybrid derivatives did not show significant acaricidal activity. ANESPE killed 83% of the R. microplus larvae at 30 mg.mL−1, while ANESPSAT killed 97% at 0.5 mg.mL−1, showing to be the most active compound. Spilanthol and ANESPSAT had similar high mortality rates for tick larvae, with LC50 values of 0.10 and 0.14 mg.mL−1 for R. microplus larvae, and 0.04 and 0.48 mg.mL−1 for A. sculptum larvae, respectively. The efficacy of spilanthol was lower against R. microplus engorged females when compared with ANESPSAT, which was highly effective (>98%) against R. microplus engorged females. The nanoemulsion with ANESPSAT was effective against tick females, preventing egg laying and achieving 100% efficacy at 2.5 mg.mL−1. Spilanthol had only 59% efficacy at 10 mg.mL−1. The results suggest that ANESPSAT, a natural product derivative, could be used in novel formulations for tick management that might be safer and environmentally friendly. 650 $aRickettsia rickettsii 650 $aBovino 650 $aCarrapato 653 $aAcmella oleracea 653 $aBovine parasite sadness 653 $aBrazilian Spotted Fever 653 $aCattle tick 653 $aControl 653 $aNanoformulation 653 $aSpilanthol 700 1 $aBRANCAGLION, G. A. 700 1 $aSANTOS, D. M. DOS 700 1 $aKAPRITCHKOFF, R. T. I. 700 1 $aCASTRO, K. N. de C. 700 1 $aCANUTO, K. M. 700 1 $aRODRIGUES, R. A. F. 700 1 $aCORREA, D. S. 700 1 $aCHAGAS, A. C. de S. 700 1 $aPASTRE, J. C. 773 $tVeterinary Parasitology$gv. 327, Apr. 2024, 110137.
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