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1. | | PICCOLI, M. L.; BRACINNI NETO, J.; CARDOSO, F. F.; SARGOLZAEI, M.; SCHENKEL, F. S. Accuracy of genotype imputation with different low density panels in Braford and Hereford cattle. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 10., 2014, Vancouver, British Columbia, Canada. Proceedings... Champaign: ASAS, 2014. 1 CD-ROM. Biblioteca(s): Embrapa Pecuária Sul. |
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Registros recuperados : 1 | |
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Registro Completo
Biblioteca(s): |
Embrapa Pecuária Sul. |
Data corrente: |
24/09/2014 |
Data da última atualização: |
24/09/2014 |
Tipo da produção científica: |
Artigo em Anais de Congresso |
Autoria: |
PICCOLI, M. L.; BRACINNI NETO, J.; CARDOSO, F. F.; SARGOLZAEI, M.; SCHENKEL, F. S. |
Afiliação: |
MARIO LUIZ PICCOLI, UFRGS; JOSÉ BRACINNI NETO, UFRGS; FERNANDO FLORES CARDOSO, CPPSUL; M. SARGOLZAEI, University of Guelph; FLÁVIO S. SCHENKEL, University of Guelph. |
Título: |
Accuracy of genotype imputation with different low density panels in Braford and Hereford cattle. |
Ano de publicação: |
2014 |
Fonte/Imprenta: |
In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 10., 2014, Vancouver, British Columbia, Canada. Proceedings... Champaign: ASAS, 2014. |
Descrição Física: |
1 CD-ROM. |
Idioma: |
Português |
Conteúdo: |
The main objective of this research was to test alternative low density SNP panels to impute Illumina 50K SNP panel genotypes in Braford and Hereford cattle. Genotypes from 3,768 Hereford, Braford and Nellore animals were used for testing imputation from low density SNP panels (3K, 6K, 8K, 15K and 20K) to the Illumina 50K SNP panel, under four different scenarios: including or not Nellore genotypes in the reference population in combination with the use or not of pedigree information. There were no significant differences in imputation accuracy among these four scenarios within each panel. However, significant differences between panels were found. The best accuracy was given by a customized 15K SNP panel, with an overall genotype concordance rate of 0.977, with 93.3% of the animals imputed with a concordance rate above 0.95. The concordance rates for the other SNP panels were 0.872, 0.952, 0.957 and 0.958 for 3K, 6K, 8K and 20K SNP panel, respectively. Therefore, in the Braford/Hereford population considered in this study, all the alternative panels denser than 3K could be used for imputing to the 50K SNP panel with an overall high imputation accuracy. However, the best results were obtained with the customized 15K SNP instead of the alternative commercial panels. The use of Nellore sire genotypes and pedigree information did not increase accuracy of imputation in this population. |
Palavras-Chave: |
Seleção genômica. |
Thesagro: |
Gado de corte. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/109000/1/Piccoli-et-al.pdf
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Marc: |
LEADER 02096nam a2200193 a 4500 001 1995739 005 2014-09-24 008 2014 bl uuuu u00u1 u #d 100 1 $aPICCOLI, M. L. 245 $aAccuracy of genotype imputation with different low density panels in Braford and Hereford cattle.$h[electronic resource] 260 $aIn: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 10., 2014, Vancouver, British Columbia, Canada. Proceedings... Champaign: ASAS$c2014 300 $c1 CD-ROM. 520 $aThe main objective of this research was to test alternative low density SNP panels to impute Illumina 50K SNP panel genotypes in Braford and Hereford cattle. Genotypes from 3,768 Hereford, Braford and Nellore animals were used for testing imputation from low density SNP panels (3K, 6K, 8K, 15K and 20K) to the Illumina 50K SNP panel, under four different scenarios: including or not Nellore genotypes in the reference population in combination with the use or not of pedigree information. There were no significant differences in imputation accuracy among these four scenarios within each panel. However, significant differences between panels were found. The best accuracy was given by a customized 15K SNP panel, with an overall genotype concordance rate of 0.977, with 93.3% of the animals imputed with a concordance rate above 0.95. The concordance rates for the other SNP panels were 0.872, 0.952, 0.957 and 0.958 for 3K, 6K, 8K and 20K SNP panel, respectively. Therefore, in the Braford/Hereford population considered in this study, all the alternative panels denser than 3K could be used for imputing to the 50K SNP panel with an overall high imputation accuracy. However, the best results were obtained with the customized 15K SNP instead of the alternative commercial panels. The use of Nellore sire genotypes and pedigree information did not increase accuracy of imputation in this population. 650 $aGado de corte 653 $aSeleção genômica 700 1 $aBRACINNI NETO, J. 700 1 $aCARDOSO, F. F. 700 1 $aSARGOLZAEI, M. 700 1 $aSCHENKEL, F. S.
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Embrapa Pecuária Sul (CPPSUL) |
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