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| Registros recuperados : 133 | |
| 101. |  | SANTOS, L. R. dos; ARAUJO, F. R.; RAMOS, C. A. do N.; GULIAS-GOMES, C. C.; GASPAR, E. B.; BENAVIDES, M. V. Tristeza parasitária bovina: resistência genética. In: ANDREOTTI, R.; KOLLER, W. W. (Ed.). Carrapatos no Brasil: biologia, controle e doenças transmitidas. Brasília, DF: Embrapa, 2013. p. 73-84.| Biblioteca(s): Embrapa Gado de Corte. |
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| 102. | | SANTOS, L. R. dos; ARAUJO, F. R.; RAMOS, C. A. do N.; GULIAS-GOMES, C. C.; GASPAR, E. B.; BENAVIDES, M. V. Tristeza parasitária bovina: resistência genética. In: ANDREOTTI, R.; KOLLER, W. W. (Ed.). Carrapatos no Brasil. Brasília, DF: Embrapa, 2013. p. 75-84.| Biblioteca(s): Embrapa Pecuária Sul. |
| |
| 103. | | REINIGER, R. C. P.; CASTRO, L. L. D. de; PINTO, N. B.; BOTELHO, F. B.; BENAVIDES, M. V.; BERNE, M. E. A. Resposta de cordeiros ao parasitismo por Haemonchus contortus previamente infectados com Haemonchus placei. In: CONGRESSO BRASILEIRO DE MEDICINA VETERINARIA, 38., 2011, Florianópolis, SC. [Anais...]. Florianópolis: Sociedade Brasileira de Medicina Veterinária, 2011.| Biblioteca(s): Embrapa Pecuária Sul. |
|  |
| 104. | | BENAVIDES, M. V.; SOUZA, C. J. H. de; MORAES, J. C. F.; BERNE, M. E. A.; HASSUM, I. C.; VIEIRA, L.; ZAROS, L.; REINIGER, R. C. P. Resposta da inoculação por Haemonchus contortus em cordeiros primo-infectados com Haemonchus placei. In: SIMPÓSIO EMBRAPA LABEX DE SANIDADE ANIMAL, 1., 2009, Campo Grande. Anais... Campo Grande: Embrapa Gado de Corte, 2009. 1 CD-ROM. Resumo em português e inglês.| Biblioteca(s): Embrapa Pecuária Sul. |
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| 105. | | RASSIER, G. L.; BORSUK, S.; PAPPEN, F.; SCAINI, C. J.; GALLINA, T.; VILLELA, M. M.; FARIAS, N. A. da R.; BENAVIDES, M. V.; BERNE, M. E. A. Toxocara spp. seroprevalence in sheep from southern Brazil. Parasitology Research, v. 112, n. 9, p. 3181-3186, 2013.| Biblioteca(s): Embrapa Pecuária Sul. |
|  |
| 106. | | SMITH, W. D.; NEWLANDS, G.; FITZPATRICK, J.; SPICKETT, A.; AMARANTE, A.; SOUZA, C. J. H. de; BENAVIDES, M. V.; BESIER, B. Towards a commercial vaccine for Haemonchosis in ruminants. In: INTERNATIONAL CONFERENCE OF THE WORLD ASSOCIATION FOR THE ADVANCEMENT OF VETERINARY PARASITOLOGY, 23., 2011, Buenos Aires. Proceedings... Buenos Aires: WAAVP, 2011. 1 CD-ROM.| Biblioteca(s): Embrapa Pecuária Sul. |
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| 107. | | MORAES, J. C. F.; SOUZA, C. J. H. de; BRAUNER, C. C.; PIMENTEL, M. A.; BENAVIDES, M. V.; FERRAZ, J. B. S. Utilização do escore de condição corporal pós-parto na identificação de vacas de corte mais férteis criadas em sistemas extensivos. Archivos Latinoamericanos de Producción Animal, Maracaibo, v. 21, n. 3, p. 149-155, 2013.| Biblioteca(s): Embrapa Pecuária Sul; Embrapa Pesca e Aquicultura. |
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| 108. | | NICIURA, S. C. M.; CRUVINEL, G. G.; MORAES, C. V.; CHAGAS, A. C. de S.; ESTEVES, S. N.; BENAVIDES, M. V.; AMARANTE, A. F. T. do. In vivo selection for Haemonchus contortus resistance to monepantel. Journal of Helminthology, v. 94, e-46, p. 1-5, 2020.| Biblioteca(s): Embrapa Pecuária Sul. |
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| 109. | | NICIURA, S. C. M.; CRUVINEL, G. G.; MORAES, C. V.; CHAGAS, A. C. de S.; ESTEVES, S. N.; BENAVIDES, M. V.; AMARANTE, A. F. T. do. In vivo selection for Haemonchus contortus resistance to monepantel. Journal of Helminthology, v. 94, e-46, p. 1-5, 2020.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 110. | | NICIURA, S. C. M.; MINHO, A. P.; MCINTYRE, J.; BENAVIDES, M. V.; OKINO, C. H.; ESTEVES, S. N.; CHAGAS, A. C. de S.; AMARANTE, A. F. T. DO. In vitro culture of parasitic stages of Haemonchus contortus. Revista Brasileira de Parasitologia Veterinária, v. 32, n. 1, 2023, e010122. 12 p.| Biblioteca(s): Embrapa Pecuária Sudeste; Embrapa Pecuária Sul. |
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| 111. | | KASHINO, S. S.; RESENDE, J.; SACCO, A. M. S.; ROCHA, C.; PROENÇA, L.; CARVALHO, W. A.; FIRMINO, A. A.; QUEROZ, R.; BENAVIDES, M. V.; GERSHWIN, L. J.; SANTOS, I. K. F. de M. Boophilus microplus: the pattern of bovine immunoglobulin isotype responses to high and low tick infestations. Experimental Parasitology, v. 110, n. 1, p. 12-21, May 2005.| Biblioteca(s): Embrapa Pecuária Sul. |
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| 112. | | SILVA, T. S. de C.; ISHIKAWA, M. M.; MACIEL, P. O.; WEBBER, D. C.; CAVICHIOLO, F.; RUSSO, M. R.; CARRIJO-MAUAD, J. R.; BENAVIDES, M. V.; FUJIMOTO, R. Y. Caracterização das propriedades piscícolas de peixes redondos da Grande Dourados, MS. Dourados: Embrapa Agropecuária Oeste, 2017. 39 p. (Embrapa Agropecuária Oeste. Documentos, 142).| Biblioteca(s): Embrapa Agropecuária Oeste; Embrapa Meio Ambiente; Embrapa Pecuária Sul; Embrapa Pesca e Aquicultura; Embrapa Tabuleiros Costeiros. |
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| 113. | | ISHIKAWA, M. M.; JERÔNIMO, G. T.; VENTURA, A. S.; PEREIRA, N, L.; SILVA, T. S. de C.; ZANON, R. B.; FUJIMOTO, R. Y.; CHAGAS, E. C.; MACIEL, P. O.; BENAVIDES, M. V.; MARTINS, M. L. Parasitos de peixes redondos produzidos na região da Grande Dourados-MS: características e possíveis soluções. Jaguariúna: Embrapa Meio Ambiente, 2016. 40 p. (Embrapa Meio Ambiente. Documentos, 106).| Biblioteca(s): Embrapa Amazônia Ocidental; Embrapa Meio Ambiente; Embrapa Pesca e Aquicultura; Embrapa Tabuleiros Costeiros. |
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| 114. | | NICIURA, S. C. M.; TIZIOTO, P. C.; MORAES, C. V.; CRUVINEL, G. G.; ALBUQUERQUE, A. C. A. de; SANTANA, R. C. M.; CHAGAS, A. C. de S.; ESTEVES, S. N.; BENAVIDES, M. V.; AMARANTE, A. F. T. do. Extreme-QTL mapping of monepantel resistance in Haemonchus contortus. Parasites Vectors, v.12, n.403, p.1-11, 2019.| Biblioteca(s): Embrapa Pecuária Sudeste; Embrapa Pecuária Sul. |
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| 115. | | HAEHLING, M. B. V.; CRUVINEL, G. G.; TOSCANO, J. H. B.; GIRALDELO, L. A.; SANTOS, I. B. dos; ESTEVES, S. N.; BENAVIDES, M. V.; BARIONI JUNIOR, W.; NICIURA, S. C. M.; CHAGAS, A. C. de S. Four single nucleotide polymorphisms (SNPs) are associated with resistance and resilience to Haemonchus contortus in Brazilian Morada Nova sheep. Veterinary Parasitology, v. 279, 2020, 109053. 11 p.| Biblioteca(s): Embrapa Pecuária Sudeste; Embrapa Pecuária Sul. |
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| 116. | | OKINO, C. H.; TOSCANO, J. H. B.; LOPES, L. G.; SILVA, M. H.; GIRALDELO, L. A.; NICIURA, S. C. M.; BENAVIDES, M. V.; ESTEVES, S. N.; CHAGAS, A. C. de S. Immune cell profiles associated with resistance against Haemonchus contortus in Morada Nova sheep. In: ANNUAL MEETING OF THE EUROPEAN FEDERATION OF ANIMAL SCIENCE, 69., 2018, Dubrovnik, Croatia. Proceedings... Dubrovnik, Croatia: Wageningen Academic Publishers, 2018. p.310. 27-31 august 2018.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 117. | | FUJIMOTO, R. Y.; CHAGAS, E. C.; ISHIKAWA, M. M.; BENAVIDES, M. V.; PEREIRA, A. M. L.; IWASHITA, M. K. P.; MACIEL, P. O.; BOIJINK, C. de L.; MAJOLO, C.; DIAS, M. T.; PEREIRA, S. L. A.; HIDE, D. M. V. Procedimentos analíticos para avaliação de doenças de peixes. Aracaju: Embrapa Tabuleiros Costeiros, 2015. 62 p. (Embrapa Tabuleiros Costeiros. Documentos, 204).| Biblioteca(s): Embrapa Amazônia Ocidental; Embrapa Meio Ambiente; Embrapa Meio-Norte; Embrapa Pesca e Aquicultura; Embrapa Roraima. |
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| 118. | | FUJIMOTO, R. Y.; CHAGAS, E. C.; ISHIKAWA, M. M.; BENAVIDES, M. V.; PEREIRA, A. M. L.; IWASHITA, M. K. P.; MACIEL, P. O.; BOIJINK, C. de L.; MAJOLO, C.; DIAS, M. T.; PEREIRA, S. L. A.; HIDE, D. M. V. Procedimentos analíticos para avaliação de doenças de peixes. Aracaju: Embrapa Tabuleiros Costeiros, 2015. 62 p. (Embrapa Tabuleiros Costeiros. Documentos, 204).| Biblioteca(s): Embrapa Tabuleiros Costeiros. |
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| 119. | | NICIURA, S. C. M.; ALBUQUERQUE, A. C. A. de; CRUVINEL, G. G.; MORAES, C.; CHAGAS, A. C. de S.; ESTEVES, S. N.; BENAVIDES, M. V.; AMARANTE, A. F. T. do. Preliminary genomic analyses of a brazillian isolate of Haemonchus contortus in a model for monepantel resistance. In: MOLECULAR AND CELLULAR BIOLOGY OF HELMINTHS, 12., 2018, Hydra, Greece. Proceedings... Hydra, Greece: [S.n], 2018. p.50. 2 - 7 September 2018.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 120. | | NICIURA, S. C. M.; CARDOSO, T. F.; IBELLI, A. M. G.; OKINO, C. H.; ANDRADE, B. G.; BENAVIDES, M. V.; CHAGAS, A. C. de S.; ESTEVES, S. N.; MINHO, A. P.; REGITANO, L. C. de A.; GONDRO, C. Multi-omics data elucidate parasite-host-microbiota interactions and resistance to Haemonchus contortus. in sheep Parasites & Vectors, v. 17, n. 102, 2024.| Biblioteca(s): Embrapa Pecuária Sudeste; Embrapa Pecuária Sul. |
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| Registros recuperados : 133 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Pecuária Sudeste; Embrapa Pecuária Sul. |
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Data corrente: |
16/03/2020 |
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Data da última atualização: |
20/04/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
HAEHLING, M. B. V.; CRUVINEL, G. G.; TOSCANO, J. H. B.; GIRALDELO, L. A.; SANTOS, I. B. dos; ESTEVES, S. N.; BENAVIDES, M. V.; BARIONI JUNIOR, W.; NICIURA, S. C. M.; CHAGAS, A. C. de S. |
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Afiliação: |
MAREI BORSCH VON HAEHLING, UNESP; GIOVANNA GABRIELLE CRUVINEL, UNICEP; JOÃO HENRIQUE BARBOSA TOSCANO, UNESP; LUCIANA APARECIDA GIRALDELO, UNICEP; ISABELLA BARBOSA DOS SANTOS, UNESP; SERGIO NOVITA ESTEVES, CPPSE; MAGDA VIEIRA BENAVIDES, CPPSUL; WALDOMIRO BARIONI JUNIOR, CPPSE; SIMONE CRISTINA MEO NICIURA, CPPSE; ANA CAROLINA DE SOUZA CHAGAS, CPPSE. |
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Título: |
Four single nucleotide polymorphisms (SNPs) are associated with resistance and resilience to Haemonchus contortus in Brazilian Morada Nova sheep. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
Veterinary Parasitology, v. 279, 2020, 109053. |
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Páginas: |
11 p. |
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ISSN: |
0304-4017 |
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DOI: |
https://doi.org/10.1016/j.vetpar.2020.109053 |
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Idioma: |
Inglês |
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Conteúdo: |
Gastrointestinal nematodes are a major constraint in sheep production. Breeding for resistance has proven to be an effective and feasible approach to address this problem. The use and investigation of genetic markers for resistance traits could accelerate genetic progress and lead to a better understanding of underlying molecular mechanisms. Thus, the aim of this study was to evaluate if five single nucleotide polymorphisms SNPs OAR2_14765360, OAR6_81718546, OAR11_62887032, OAR12_69606944 and OAR15_59871543 are associated with resistance and resilience traits in a flock of the Morada Nova sheep breed. Lambs were submitted to two consecutive parasite challenges by oral infection with 4000 infective larvae L3) of Haemonchus contortus. Fecal egg counts (FEC), packed cell volume (PVC) and body weight were measured every one or two weeks for 42 days in each trial. DNA samples from 287 lambs, 131 ewes and 4 rams were amplified by ARMS-PCR or PCR-RFLP and genotypes were determined. Analysis of variance (ANOVA) was used for association analyses between genotypes and phenotypes. In case of significant association, the allele substitution effect was calculated based on a linear model. OAR2_14765360 and OAR12_69606944 were associated with FEC, and OAR12_69606944 also had significant effects on PCV and weight gain, showing favourable associations of the CC genotype with all evaluated traits. Both OAR6_81718546 and OAR11_62887032 were associated with weight gain, and OAR6_81718546 had an additional effect on PCV. OAR15_59871543 was not polymorphic in the population. OAR6_81718546 and OAR12_69606944 presented significant allele substitution effects of -1.06 ± 0.52 kg for the T allele on final body weight and 0.74 ± 0.32 for the C allele in PCV of the same sampling date, respectively. This is the first report of SNPs associated with gastrointestinal nematode resistance in this sheep breed. Our findings support the existence of quantitatice trait loci (QTL) for resistance and resilience in linkage disequilibrium with the polymorphic SNPs and suggest their future use for explorations of these traits in Morada Nova sheep. MenosGastrointestinal nematodes are a major constraint in sheep production. Breeding for resistance has proven to be an effective and feasible approach to address this problem. The use and investigation of genetic markers for resistance traits could accelerate genetic progress and lead to a better understanding of underlying molecular mechanisms. Thus, the aim of this study was to evaluate if five single nucleotide polymorphisms SNPs OAR2_14765360, OAR6_81718546, OAR11_62887032, OAR12_69606944 and OAR15_59871543 are associated with resistance and resilience traits in a flock of the Morada Nova sheep breed. Lambs were submitted to two consecutive parasite challenges by oral infection with 4000 infective larvae L3) of Haemonchus contortus. Fecal egg counts (FEC), packed cell volume (PVC) and body weight were measured every one or two weeks for 42 days in each trial. DNA samples from 287 lambs, 131 ewes and 4 rams were amplified by ARMS-PCR or PCR-RFLP and genotypes were determined. Analysis of variance (ANOVA) was used for association analyses between genotypes and phenotypes. In case of significant association, the allele substitution effect was calculated based on a linear model. OAR2_14765360 and OAR12_69606944 were associated with FEC, and OAR12_69606944 also had significant effects on PCV and weight gain, showing favourable associations of the CC genotype with all evaluated traits. Both OAR6_81718546 and OAR11_62887032 were associated with weight gain, and OAR6_81718546 had an... Mostrar Tudo |
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Palavras-Chave: |
Host resistance; Morada Nova sheep; Parasite challenge; SNPs. |
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Thesaurus NAL: |
Genetic markers. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
|
Marc: |
LEADER 03156naa a2200325 a 4500
001 2121271
005 2020-04-20
008 2020 bl uuuu u00u1 u #d
022 $a0304-4017
024 7 $ahttps://doi.org/10.1016/j.vetpar.2020.109053$2DOI
100 1 $aHAEHLING, M. B. V.
245 $aFour single nucleotide polymorphisms (SNPs) are associated with resistance and resilience to Haemonchus contortus in Brazilian Morada Nova sheep.$h[electronic resource]
260 $c2020
300 $a11 p.
520 $aGastrointestinal nematodes are a major constraint in sheep production. Breeding for resistance has proven to be an effective and feasible approach to address this problem. The use and investigation of genetic markers for resistance traits could accelerate genetic progress and lead to a better understanding of underlying molecular mechanisms. Thus, the aim of this study was to evaluate if five single nucleotide polymorphisms SNPs OAR2_14765360, OAR6_81718546, OAR11_62887032, OAR12_69606944 and OAR15_59871543 are associated with resistance and resilience traits in a flock of the Morada Nova sheep breed. Lambs were submitted to two consecutive parasite challenges by oral infection with 4000 infective larvae L3) of Haemonchus contortus. Fecal egg counts (FEC), packed cell volume (PVC) and body weight were measured every one or two weeks for 42 days in each trial. DNA samples from 287 lambs, 131 ewes and 4 rams were amplified by ARMS-PCR or PCR-RFLP and genotypes were determined. Analysis of variance (ANOVA) was used for association analyses between genotypes and phenotypes. In case of significant association, the allele substitution effect was calculated based on a linear model. OAR2_14765360 and OAR12_69606944 were associated with FEC, and OAR12_69606944 also had significant effects on PCV and weight gain, showing favourable associations of the CC genotype with all evaluated traits. Both OAR6_81718546 and OAR11_62887032 were associated with weight gain, and OAR6_81718546 had an additional effect on PCV. OAR15_59871543 was not polymorphic in the population. OAR6_81718546 and OAR12_69606944 presented significant allele substitution effects of -1.06 ± 0.52 kg for the T allele on final body weight and 0.74 ± 0.32 for the C allele in PCV of the same sampling date, respectively. This is the first report of SNPs associated with gastrointestinal nematode resistance in this sheep breed. Our findings support the existence of quantitatice trait loci (QTL) for resistance and resilience in linkage disequilibrium with the polymorphic SNPs and suggest their future use for explorations of these traits in Morada Nova sheep.
650 $aGenetic markers
653 $aHost resistance
653 $aMorada Nova sheep
653 $aParasite challenge
653 $aSNPs
700 1 $aCRUVINEL, G. G.
700 1 $aTOSCANO, J. H. B.
700 1 $aGIRALDELO, L. A.
700 1 $aSANTOS, I. B. dos
700 1 $aESTEVES, S. N.
700 1 $aBENAVIDES, M. V.
700 1 $aBARIONI JUNIOR, W.
700 1 $aNICIURA, S. C. M.
700 1 $aCHAGAS, A. C. de S.
773 $tVeterinary Parasitology$gv. 279, 2020, 109053.
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