| |
|
|
| Registros recuperados : 42 | |
| 12. |  | ERVEN, B.; ROHWEDER, D.; BARRETO, I.; KONSEN, O. G. Aspectos economicos do melhoramento de pastagens com especies de inverno, na regiao fisiografica dos campos de cima da serra, Rio Grande do Sul, Brasil, 1969. Porto Alegre: UFRGS. Faculdade de Ciencias Economicas. Centro de Estudos e Pesquisas Economicas, 1972. 38p. (Universidade do Rio Grande do Sul. Estudos e trabalhos mimeografados, 18).| Biblioteca(s): Embrapa Gado de Leite. |
|   |
| 19. | | MOSELE, S. H.; DOSSA, D.; BARRETO, I.; WACZUK, A. Rentabilidade da erva-mate com alta tecnologia em Machadinho, RS. In: CONGRESSO SUL-AMERICANO DA ERVA MATE, 2.; REUNIAO TECNICA DA ERVA MATE, 3., 2000, Encantado. Anais. Porto Alegre: Comissao dos Organizadores / Universidade do Rio Grande do Sul / Fundacao Estadual de Pesquisa Agropecuaria, 2000. p.223-226.| Biblioteca(s): Embrapa Florestas. |
|  |
| Registros recuperados : 42 | |
|
|
|
Registro Completo
|
Biblioteca(s): |
Embrapa Tabuleiros Costeiros. |
|
Data corrente: |
21/12/2022 |
|
Data da última atualização: |
21/12/2022 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Circulação/Nível: |
A - 1 |
|
Autoria: |
SENA FILHO, J. G. de; ALMEIDA, A. S. de; PINTO ZEVALLOS, D.; BARRETO, I. C.; CAVALCANTI, S. C. de H.; NUNES, R.; TEODORO, A. V.; XAVIER, H. S.; BARBOSA FILHO, J. M.; GUAN, L.; NEVES, A. L. A.; DURINGER, J. M. |
|
Afiliação: |
JOSE GUEDES DE SENA FILHO, CPATC; ANDERSON SOARES DE ALMEIDA, UFS; DELIA PINTO ZEVALLOS; IGHOR COSTA BARRETO; SOCRATES CABRAL DE HOLANDA CAVALCANTI; ROGERIA NUNES; ADENIR VIEIRA TEODORO, CPATC; HAROUDO SATIRO XAVIER; JOSE MARIA BARBOSA FILHO; LELUO GUAN; ANDRE L. A. NEVES; JENNIFER M. DURINGER. |
|
Título: |
From plant scent defense to biopesticide discovery: evaluation of toxicity and acetylcholinesterase docking properties for Lamiaceae monoterpenes. |
|
Ano de publicação: |
2023 |
|
Fonte/Imprenta: |
Crop Protection, v. 164, 106126, 2023. |
|
Idioma: |
Inglês |
|
Conteúdo: |
Monoterpenes are a highly diverse group of chemical scents that originate from plant secondary metabolic processes, one purpose of which is to serve as a defense against herbivores. Plant-derived monoterpenes pro- duced from Lamiaceae species have demonstrated acaricidal activity against pest mites and ticks. However, the mechanism by which these compounds carry out the demise of this group of arachnids is poorly understood. Here, we review the chemistry and bioactivity of these promising compounds and subsequently assess their potential toxicity to mites and ticks through measurement of their docking ability to amino acid residues of the binding pocket of Drosophila melanogaster acetylcholinesterase (AChE). We identified 27 monoterpenes of the Lamiaceae family from the literature that were effective against mite (Varroidae, Tetranychidae, Eriophyidae) and tick (Ixodidae) species that are problematic in agricultural production. Screening of these compounds showed that monoterpenoids possessing methyl groups, such as carvacrol, linalool, ?-terpineol, bornyl acetate, and terpine-4-ol, strongly bind to D. melanogaster AChE. Linalool, which fits into the binding pocket in the amino acid catalytic triad of AChE (oxyanion hole residues, hydrogen bond interaction with GLU 237, and anionic binding with TRP 83), was identified as the most promising target for further optimization studies. We propose that monoterpenes which interact strongly with amino acid residues of the AChE receptor be targeted for development of effective, naturally produced biocontrol pesticides, as this model demonstrates potential for discovery of new acaricide compounds in a high throughput manner MenosMonoterpenes are a highly diverse group of chemical scents that originate from plant secondary metabolic processes, one purpose of which is to serve as a defense against herbivores. Plant-derived monoterpenes pro- duced from Lamiaceae species have demonstrated acaricidal activity against pest mites and ticks. However, the mechanism by which these compounds carry out the demise of this group of arachnids is poorly understood. Here, we review the chemistry and bioactivity of these promising compounds and subsequently assess their potential toxicity to mites and ticks through measurement of their docking ability to amino acid residues of the binding pocket of Drosophila melanogaster acetylcholinesterase (AChE). We identified 27 monoterpenes of the Lamiaceae family from the literature that were effective against mite (Varroidae, Tetranychidae, Eriophyidae) and tick (Ixodidae) species that are problematic in agricultural production. Screening of these compounds showed that monoterpenoids possessing methyl groups, such as carvacrol, linalool, ?-terpineol, bornyl acetate, and terpine-4-ol, strongly bind to D. melanogaster AChE. Linalool, which fits into the binding pocket in the amino acid catalytic triad of AChE (oxyanion hole residues, hydrogen bond interaction with GLU 237, and anionic binding with TRP 83), was identified as the most promising target for further optimization studies. We propose that monoterpenes which interact strongly with amino acid residues of the AChE recept... Mostrar Tudo |
|
Palavras-Chave: |
Ácaros; Biopesticida. |
|
Thesagro: |
Aroma; Óleo Essencial; Pesticida. |
|
Thesaurus NAL: |
Essential oils. |
|
Categoria do assunto: |
-- |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1150182/1/From-plant-scent-defense-to-biopeseicide....pdf
|
|
Marc: |
LEADER 02646naa a2200325 a 4500
001 2150182
005 2022-12-21
008 2023 bl uuuu u00u1 u #d
100 1 $aSENA FILHO, J. G. de
245 $aFrom plant scent defense to biopesticide discovery$bevaluation of toxicity and acetylcholinesterase docking properties for Lamiaceae monoterpenes.$h[electronic resource]
260 $c2023
520 $aMonoterpenes are a highly diverse group of chemical scents that originate from plant secondary metabolic processes, one purpose of which is to serve as a defense against herbivores. Plant-derived monoterpenes pro- duced from Lamiaceae species have demonstrated acaricidal activity against pest mites and ticks. However, the mechanism by which these compounds carry out the demise of this group of arachnids is poorly understood. Here, we review the chemistry and bioactivity of these promising compounds and subsequently assess their potential toxicity to mites and ticks through measurement of their docking ability to amino acid residues of the binding pocket of Drosophila melanogaster acetylcholinesterase (AChE). We identified 27 monoterpenes of the Lamiaceae family from the literature that were effective against mite (Varroidae, Tetranychidae, Eriophyidae) and tick (Ixodidae) species that are problematic in agricultural production. Screening of these compounds showed that monoterpenoids possessing methyl groups, such as carvacrol, linalool, ?-terpineol, bornyl acetate, and terpine-4-ol, strongly bind to D. melanogaster AChE. Linalool, which fits into the binding pocket in the amino acid catalytic triad of AChE (oxyanion hole residues, hydrogen bond interaction with GLU 237, and anionic binding with TRP 83), was identified as the most promising target for further optimization studies. We propose that monoterpenes which interact strongly with amino acid residues of the AChE receptor be targeted for development of effective, naturally produced biocontrol pesticides, as this model demonstrates potential for discovery of new acaricide compounds in a high throughput manner
650 $aEssential oils
650 $aAroma
650 $aÓleo Essencial
650 $aPesticida
653 $aÁcaros
653 $aBiopesticida
700 1 $aALMEIDA, A. S. de
700 1 $aPINTO ZEVALLOS, D.
700 1 $aBARRETO, I. C.
700 1 $aCAVALCANTI, S. C. de H.
700 1 $aNUNES, R.
700 1 $aTEODORO, A. V.
700 1 $aXAVIER, H. S.
700 1 $aBARBOSA FILHO, J. M.
700 1 $aGUAN, L.
700 1 $aNEVES, A. L. A.
700 1 $aDURINGER, J. M.
773 $tCrop Protection$gv. 164, 106126, 2023.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Tabuleiros Costeiros (CPATC) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
