| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Recursos Genéticos e Biotecnologia. Para informações adicionais entre em contato com cenargen.biblioteca@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
|
Data corrente: |
07/12/2015 |
|
Data da última atualização: |
20/06/2024 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
PETRIZ, B. A.; ALMEIDA, J. A.; GOMES, C. P. C.; PEREIRA, R. W.; MURAD, A. M.; FRANCO, O. L. |
|
Afiliação: |
Bernardo A. Petriz, UCB; Jeeser A. Almeida, UCB; Clarissa P. C. Gomes, UCB; Rinaldo W. Pereira, UCB; ANDRE MELRO MURAD, CENARGEN; Octavio l. Franco, UCB. |
|
Título: |
NanoUPLC/MSE proteomic analysis reveals modulation on left ventricle proteome from hypertensive rats after exercise training. |
|
Ano de publicação: |
2015 |
|
Fonte/Imprenta: |
Journal of Proteomics, v. 113, p. 351-365, 2015. |
|
Idioma: |
Inglês |
|
Conteúdo: |
NanoUPLC/MSE was used to verify the effects of 8 weeks of low (SHR-LIT = 4) and high (SHR-HIT = 4) intensity training over the left ventricle proteome of hypertensive rats (SHR-C = 4). Training enhanced the aerobic capacity and reduced the systolic blood pressure in all exercised rats.NanoUPLC/MSE identified 250 proteins, with 233 in common to all groups and 16 exclusive to SHR-C, 2 to SHR-LIT, and 2 to the SHR-HIT. Cardiac hypertrophy related proteins appeared only in SHR-C. The SHR-LIT enhanced the abundance of 30 proteins and diminished 6, while SHR-HIT enhanced the abundance of 39 proteins and reduced other 7. The levels of metabolic (? and ?-enolase, adenine phosphoribosultransferase, and cytochrome b-c1), myofibril (myosin light chain 4, tropomyosin ? and ?-chain), and transporter proteins (hemoglobin, serum albumin, and hemopexin)were increased by both intensities. Transcription regulator and histone variants were enhanced by SHR-LIT and SHR-HIT respectively. SHR-LIT reduced the concentration of myosin binding protein C, while desmin and membrane voltage dependent anion selective channel protein-3 were reduced only by SHR-HIT. In addition, polyubiquitin B and C, and transcription regulators decreased in both intensities. Exercise also increased the concentration of anti-oxidant proteins, peroxiredozin-6 and glutathione peroxidase-1. Biological significance Pathologic left ventricle hypertrophy if one of the major outcomes of hypertension being a strong predictor of heart failure. Among the various risk factors for cardiovascular disorders, arterial hypertension is responsible for the highest rates of mortality worldwide. In this way,this present study contribute to the understanding of the molecular mechanisms involved in the attenuation of hypertension and the regression of pathological cardiac hypertrophy induced by exercise training. MenosNanoUPLC/MSE was used to verify the effects of 8 weeks of low (SHR-LIT = 4) and high (SHR-HIT = 4) intensity training over the left ventricle proteome of hypertensive rats (SHR-C = 4). Training enhanced the aerobic capacity and reduced the systolic blood pressure in all exercised rats.NanoUPLC/MSE identified 250 proteins, with 233 in common to all groups and 16 exclusive to SHR-C, 2 to SHR-LIT, and 2 to the SHR-HIT. Cardiac hypertrophy related proteins appeared only in SHR-C. The SHR-LIT enhanced the abundance of 30 proteins and diminished 6, while SHR-HIT enhanced the abundance of 39 proteins and reduced other 7. The levels of metabolic (? and ?-enolase, adenine phosphoribosultransferase, and cytochrome b-c1), myofibril (myosin light chain 4, tropomyosin ? and ?-chain), and transporter proteins (hemoglobin, serum albumin, and hemopexin)were increased by both intensities. Transcription regulator and histone variants were enhanced by SHR-LIT and SHR-HIT respectively. SHR-LIT reduced the concentration of myosin binding protein C, while desmin and membrane voltage dependent anion selective channel protein-3 were reduced only by SHR-HIT. In addition, polyubiquitin B and C, and transcription regulators decreased in both intensities. Exercise also increased the concentration of anti-oxidant proteins, peroxiredozin-6 and glutathione peroxidase-1. Biological significance Pathologic left ventricle hypertrophy if one of the major outcomes of hypertension being a strong predictor of he... Mostrar Tudo |
|
Palavras-Chave: |
Análise proteômica; Hipertensão. |
|
Categoria do assunto: |
-- |
|
Marc: |
LEADER 02514naa a2200205 a 4500
001 2030868
005 2024-06-20
008 2015 bl uuuu u00u1 u #d
100 1 $aPETRIZ, B. A.
245 $aNanoUPLC/MSE proteomic analysis reveals modulation on left ventricle proteome from hypertensive rats after exercise training.$h[electronic resource]
260 $c2015
520 $aNanoUPLC/MSE was used to verify the effects of 8 weeks of low (SHR-LIT = 4) and high (SHR-HIT = 4) intensity training over the left ventricle proteome of hypertensive rats (SHR-C = 4). Training enhanced the aerobic capacity and reduced the systolic blood pressure in all exercised rats.NanoUPLC/MSE identified 250 proteins, with 233 in common to all groups and 16 exclusive to SHR-C, 2 to SHR-LIT, and 2 to the SHR-HIT. Cardiac hypertrophy related proteins appeared only in SHR-C. The SHR-LIT enhanced the abundance of 30 proteins and diminished 6, while SHR-HIT enhanced the abundance of 39 proteins and reduced other 7. The levels of metabolic (? and ?-enolase, adenine phosphoribosultransferase, and cytochrome b-c1), myofibril (myosin light chain 4, tropomyosin ? and ?-chain), and transporter proteins (hemoglobin, serum albumin, and hemopexin)were increased by both intensities. Transcription regulator and histone variants were enhanced by SHR-LIT and SHR-HIT respectively. SHR-LIT reduced the concentration of myosin binding protein C, while desmin and membrane voltage dependent anion selective channel protein-3 were reduced only by SHR-HIT. In addition, polyubiquitin B and C, and transcription regulators decreased in both intensities. Exercise also increased the concentration of anti-oxidant proteins, peroxiredozin-6 and glutathione peroxidase-1. Biological significance Pathologic left ventricle hypertrophy if one of the major outcomes of hypertension being a strong predictor of heart failure. Among the various risk factors for cardiovascular disorders, arterial hypertension is responsible for the highest rates of mortality worldwide. In this way,this present study contribute to the understanding of the molecular mechanisms involved in the attenuation of hypertension and the regression of pathological cardiac hypertrophy induced by exercise training.
653 $aAnálise proteômica
653 $aHipertensão
700 1 $aALMEIDA, J. A.
700 1 $aGOMES, C. P. C.
700 1 $aPEREIRA, R. W.
700 1 $aMURAD, A. M.
700 1 $aFRANCO, O. L.
773 $tJournal of Proteomics$gv. 113, p. 351-365, 2015.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 18 | |
| 6. |  | MACHADO, R. C.; AMARAL, C. D. B. do; NOBREGA, J. de A.; NOGUEIRA, A. R. de A. Multielemental determination of As, Bi, Ge, Sb, and Sn in agricultural samples using hydride generation coupled to microwave-induced plasma optical emission spectrometry. Journal of Agricultural and Food Chemistry, v. 65, n. 23, p. 4839-4842, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
|    |
| 8. | | AMARAL, C. D. B. do; SCHIAVO, D.; BARROS, J. A. V. de A.; MACHADO, R. C.; NOGUEIRA, A. R. de A.; NOBREGA, J. de A. Characterization of synchronous vertical dual view inductively coupled plasma optical emission spectrometry with application for water analysis. Analytical Letters, v. 49, n. 13, p. 1-7, 2016.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 3 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
| |
| 9. | | AMARAL, C. D. B. do; MACHADO, R. C.; BARROS, J. A. V. de A.; VIRGILIO, A.; SCHIAVO, D.; NOGUEIRA, A. R. de A.; NOBREGA, J. de A. Determination of rare earth elements in geological and agricultural samples by ICP-OES. Espectroscopy, v. 32, n. 10, p. 2-6, 2017.| Tipo: Artigo de Divulgação na Mídia |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
| |
| 10. | | AMARAL, C. D. B. do; MACHADO, R. C.; BARROS, J. A. V. de A.; VIRGILIO, A.; SCHIAVO, D.; NOGUEIRA, A. R. de A.; NOBREGA, J. de A. Determination of rare earth elements in geological samples using the agilent SVDV ICP-OES. In: WINTER CONFERENCE ON PLASMA SPECTROCHEMISTRY, 2016, Tucson, Arizona. Proceedings... Tucson, Arizona: Winter Conference on Plasma Spectrochemistry, 2016. 5p.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
|  |
| 12. | | SILVA, C. S. da; BIANCHI, S. R.; AMARAL, C. D. B. do; SOUZA, G. B. de; NOGUEIRA, A. R. de A. Estudos de homogeneidade para determinação de macro e micronutrientes em fosfatos de rocha candidato a material de referência. In: ENCONTRO NACIONAL DE METODOLOGIAS E GESTÃO DE LABORATÓRIOS, 18.; SIMPÓSIO SOBRE PROCEDIMENTOS ANALÍTICOS E AS RASTREABILIDADE DOS RESULTADOS NA AGROPECUÁRIA, 5., 2013. Salvador, Ba. Resumo... Brasília: Embrapa, MAPA, Governo Federal, 2013. 1 p.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Solos. |
| |
| 13. | | MACHADO, R. C.; VIRGILIO, A.; AMARAL, C. D. B. do; SCHIAVO, D.; NOBREGA, J. de A.; NOGUEIRA, A. R. de A. Evaluation of inductively coupled plasma tandem mass spectrometry for determination of as in agricultural inputs with high REE contents. Journal of the Brazilian Chemical Society, v. 27, n. 11, p. 2076-2081, 2016.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
| |
| 14. | | AMARAL, C. D. B. do; MACHADO, R. C.; VIRGILIO, A.; SCHIAVO, D.; NOGUEIRA, A. R. de A.; NOBREGA, J. de A. Critical evaluation of internal standardization in ICP tandem mass spectrometry and feasibility of the oxygen reaction for boron determination in plants. In: Journal of Analytical Atomic Spectrometry, v.31, issue 6, p. 1179-1184, 2016| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
| |
| 15. | | MOREIRA, L. S; COSTA, F. S; MACHADO, R. C.; NOGUEIRA, A. R. de A.; GONZALEZ, M. H.; SILVA, E. G. P. da; AMARAL, C. D. B. do. Self-organizing map applied to the choice of internal standards for the determination of Cd, Pb, Sn, and platinum group elements by inductively coupled plasma mass spectrometry. Talanta, v. 233, oct. 2021, 122534. 6 p.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
| |
| 16. | | FERREIRA, N. DOS S.; COSTA, P. H. DA; SÁ, I. P. DE; BERNARDO, V. S.; TORRES, F. F.; FIGUEIREDO, J. G.; AMARAL, C. D. B. DO; NOGUEIRA, A. R. de A.; SILVA, D. G. H. DA; GONZALEZ, M. H. Arsenic bioaccumulation and biotransformation in different tissues of Nile tilapia (Oreochromis niloticus): a comparative study between As(III) and As(V) exposure and evaluation of antagonistic effects of selenium. Chemosphere, v. 359, July 2024, 142289.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
| |
| 17. | | AMARAL, C. D. B. do; MACHADO, R. C.; BERNARDI, A. C. de C.; SOUZA, G. B. de; BALIEIRO, F. de C.; POLIDORO, J. C.; NOBREGA, J. de A.; NOGUEIRA, A. R. de A. Análise inorgânica de amostras de alfafa (Medicago sativa) cultivadas em solo corrigido com gesso agrícola usando MIP OES. In: ENCONTRO NACIONAL DE QUÍMICA ANALÍTICA, 18., 2016, Florianópolis, SC. Anais... Florianópolis, SC: ENQA, 2016.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste; Embrapa Solos. |
| |
| 18. | | ROSA, L. K.; COSTA, F. S.; HAUAGGE, C. M.; MOBILE, R. Z.; LIMA, A. A. S. de; AMARAL, C. D. B. do; MACHADO, R. C.; NOGUEIRA, A. R. de A.; BRANCHER, J. A.; ARAUJO, M. R. DE. Oral health, organic and inorganic saliva composition of men with Schizophrenia: case-control study. Journal of Trace Elements in Medicine and Biology, v.66, jul. 2021, 126743. 8 p.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
| |
| Registros recuperados : 18 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
