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| 41. |  | SOUZA, A. S. DE Q.; SOUSA, J. A. C. DE; PINTO, C. S.; ALVES FILHO, E. G.; PEREIRA, R. de C. A.; BRITO, E. S. de; CANUTO, K. M.; LEAL, L. K. A. M. Untargeted GC/MS-based approach for identification of anti-inflammatory alkaloids from Hippeastrum elegans (Amaryllidaceae) using a human neutrophil model. Journal of Pharmaceutical and Biomedical Analysis, v. 199, 114061, 2021.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 42. | | GUEDES, J. A. C.; ALVES FILHO, E. G.; RODRIGUES, T. H. S.; SILVA, M. F. S.; SOUZA, F. V. D.; SILVA, L. M. A. e; ALVES, R. E.; CANUTO, K. M.; BRITO, E. S. de; PESSOA, C. O.; NASCIMENTO, R. F.; ZOCOLO, G. J. Metabolic profile and cytotoxicity of non-polar extracts of pineapple leaves and chemometric analysis of different pineapple cultivars. Industrial Crops and Products, v. 124, p. 466-474, 2018.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 43. | | GUEDES, J. A. C.; ALVES FILHO, E. G.; RODRIGUES, T. H. S.; SILVA, M. F. S.; SOUZA, F. V. D.; SILVA, L. M. A. e; ALVES, R. E.; CANUTO, K. M.; BRITO, E. S. de; PESSOA, C. O.; NASCIMENTO, R. F.; ZOCOLO, G. J. Metabolic profile and cytotoxicity of non-polar extracts of pineapple leaves and chemometric analysis of different pineapple cultivars. I Industrial Crops and Products, v. 124, p. 466-474, 2018.| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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| 44. | | CARVALHO, M. M.; ALVES FILHO, E. G.; SILVA, L. M. A. e; MARTINS, F. I. C. C.; MATIOLI, A. L.; OLIVEIRA, E. E.; RODRIGUES, T. H. S.; FERREIRA, C. L. L. F.; SILVA, N. M. da; ZOCOLO, G. J.; LINDNER, J. de D. Chemometric evaluation of the metabolites and volatile profiles of mite-ripened cheeses. International Dairy Journal, v. 110, art. no. 104806, 2020.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 45. | | PAIVA, J. R. DE; SOUZA, A. S. DE Q.; PEREIRA, R. de C. A.; RIBEIRO, P. R. V.; ALVES FILHO, E. G.; SILVA, L. M. A. e; ZOCOLO, G. J.; BRITO, E. S. de; ALVES, D. R.; MORAIS, S. M. DE; TAVARES, J.; PINTO, F. DAS C. L.; ANDRADE, G. M. DE; PESSOA, O. D. L.; CANUTO, K. M. Chemical composition and anticholinesterase activity of cultivated bulbs from Hippeastrum elegans, a potential tropical source of bioactive alkaloids. Phytochemistry Letters, v. 43, June, p. 27-34, 2021.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 46. | | MACEDO, J. J. N.; SANCHES, A. G.; RABELO, M. C.; LOPES, M. A.; FREITAS, V. S.; SILVEIRA, A. G.; MOURA, C. F. H.; SILVA, E. de O.; GALLÃO, M. I.; GOMES-FILHO, E.; ALVES-FILHO, E. G.; MIRANDA, M. R. A. Pulsed light influences several metabolic routes, delaying ripening and improving the postharvest quality of acerola. Scientia Horticulturae, 307, 111505, 2023.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 47. | | SANTOS, F. A.; VIANA, A. F. S. C.; NUNES, P. I. G.; PORTELA, B. Y. M.; ALVES, A. P. N. N.; VIANA, D. DE A.; CARVALHO, K. R.; PEREIRA, R. de C. A.; RIBEIRO, P. R. V.; ALVES FILHO, E. G.; BRITO, E. S. de; SILVEIRA, E. R.; CANUTO, K. M. UPLC-QTOF-MS/MS-based metabolomic approach and gastroprotective effect of two chemotypes of Egletes viscosa (L.) less. against ethanol-induced gastric ulcer in mice. Journal of Ethnopharmacology, 116348, june 2023.| Biblioteca(s): Embrapa Alimentos e Territórios. |
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| Registros recuperados : 47 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Mandioca e Fruticultura. Para informações adicionais entre em contato com cnpmf.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Mandioca e Fruticultura. |
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Data corrente: |
25/09/2018 |
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Data da última atualização: |
25/09/2018 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
GUEDES, J. A. C.; ALVES FILHO, E. G.; RODRIGUES, T. H. S.; SILVA, M. F. S.; SOUZA, F. V. D.; SILVA, L. M. A. e; ALVES, R. E.; CANUTO, K. M.; BRITO, E. S. de; PESSOA, C. O.; NASCIMENTO, R. F.; ZOCOLO, G. J. |
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Afiliação: |
Jhonyson Arruda Carvalho Guedes, Universidade Federal do Ceará; Elenilson de Godoy Alves Filho, Embrapa Agroindústria Tropical (bolsista); TIGRESSA HELENA SOARES RODRIGUES, CNPAT; Maria Francilene Souza Silva, Universidade Federal do Ceará; FERNANDA VIDIGAL DUARTE SOUZA, CNPMF; LORENA MARA ALEXANDRE E SILVA, CNPAT; RICARDO ELESBAO ALVES, CNPAT; KIRLEY MARQUES CANUTO, CNPAT; EDY SOUSA DE BRITO, CNPAT; Cláudia do Ó Pessoa, Universidade Federal do Ceará; Ronaldo Ferreira Nascimento, Universidade Federal do Ceará; GUILHERME JULIAO ZOCOLO, CNPAT. |
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Título: |
Metabolic profile and cytotoxicity of non-polar extracts of pineapple leaves and chemometric analysis of different pineapple cultivars. I |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Industrial Crops and Products, v. 124, p. 466-474, 2018. |
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Idioma: |
Inglês |
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Conteúdo: |
The use of co-products from the fruit agroindustry as a source of bioactive molecules presents economic advantages, since these compounds are highly available and inexpensive. Therefore, the present study aimed to evaluate their qualitative chemical composition followed by multivariate analysis, and to correlate the results with those of the cytotoxicity tests. The non-polar metabolic profiles of the leaves of seven commercial pineapple (Ananas comosus (L.) Merr.) cultivars were investigated by using GC?MS. Twenty-seven metabolites were identified from the seven hexanic extracts. Multivariate analysis (Hierarchical Cluster Analysis, Principal Component Analysis and Partial Least Squares) revealed significant differences in the metabolic fingerprint of the different cultivars. Overall, the hexanic extracts of the seven cultivars of pineapple leaves showed promising antitumor activity against the six tumor lines tested (colon, leukemia, prostate, astrocytoma, breast and cervix). Correlation of the chemometric data, qualitative analysis, and cytotoxic tests allowed us to determine the possible biomarkers responsible for each specific antitumor activity. This study demonstrates a great valuation potential of a co-product little explored in the agroindustry of foods through the prospection of biologically active compounds. |
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Palavras-Chave: |
GC MS. |
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Thesagro: |
Abacaxi. |
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Thesaurus NAL: |
Ananas; Cytotoxicity; Multivariate analysis. |
|
Categoria do assunto: |
-- |
|
Marc: |
LEADER 02272naa a2200313 a 4500
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100 1 $aGUEDES, J. A. C.
245 $aMetabolic profile and cytotoxicity of non-polar extracts of pineapple leaves and chemometric analysis of different pineapple cultivars. I$h[electronic resource]
260 $c2018
520 $aThe use of co-products from the fruit agroindustry as a source of bioactive molecules presents economic advantages, since these compounds are highly available and inexpensive. Therefore, the present study aimed to evaluate their qualitative chemical composition followed by multivariate analysis, and to correlate the results with those of the cytotoxicity tests. The non-polar metabolic profiles of the leaves of seven commercial pineapple (Ananas comosus (L.) Merr.) cultivars were investigated by using GC?MS. Twenty-seven metabolites were identified from the seven hexanic extracts. Multivariate analysis (Hierarchical Cluster Analysis, Principal Component Analysis and Partial Least Squares) revealed significant differences in the metabolic fingerprint of the different cultivars. Overall, the hexanic extracts of the seven cultivars of pineapple leaves showed promising antitumor activity against the six tumor lines tested (colon, leukemia, prostate, astrocytoma, breast and cervix). Correlation of the chemometric data, qualitative analysis, and cytotoxic tests allowed us to determine the possible biomarkers responsible for each specific antitumor activity. This study demonstrates a great valuation potential of a co-product little explored in the agroindustry of foods through the prospection of biologically active compounds.
650 $aAnanas
650 $aCytotoxicity
650 $aMultivariate analysis
650 $aAbacaxi
653 $aGC MS
700 1 $aALVES FILHO, E. G.
700 1 $aRODRIGUES, T. H. S.
700 1 $aSILVA, M. F. S.
700 1 $aSOUZA, F. V. D.
700 1 $aSILVA, L. M. A. e
700 1 $aALVES, R. E.
700 1 $aCANUTO, K. M.
700 1 $aBRITO, E. S. de
700 1 $aPESSOA, C. O.
700 1 $aNASCIMENTO, R. F.
700 1 $aZOCOLO, G. J.
773 $tIndustrial Crops and Products$gv. 124, p. 466-474, 2018.
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