| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Agroenergia. Para informações adicionais entre em contato com cnpae.biblioteca@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Agroenergia. |
|
Data corrente: |
05/07/2017 |
|
Data da última atualização: |
12/01/2018 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
MOURA, L. T. S.; SOUZA, D. P. M.; MENDONCA, S.; RIBEIRO, J. A. de A.; SOUSA, L. F.; RAMOS, A. T.; MAIORKA, P. C.; ARAÚJO, V. L.; MARUO, V. M. |
|
Afiliação: |
LAIANE TEIXEIRA SOUSA MOURA; DOMENICA PALOMARIS MARIANO SOUZA; SIMONE MENDONCA, CNPAE; JOSE ANTONIO DE AQUINO RIBEIRO, CNPAE; LUCIANO FERNANDES SOUSA; ADRIANO TONY RAMOS; PAULO CÉSAR MAIORKA; VERA LÚCIA DE ARAÚJO; VIVIANE MAYUMI MARUO. |
|
Título: |
Histopathological and Reproductive Evaluation in Male Rats Fed Jatropha curcas Seed Cake with or without Alkaline Hydrolysis and Subjected to Heat Treatment. |
|
Ano de publicação: |
2017 |
|
Fonte/Imprenta: |
BioMed Research International, v. 2017, artigo 6123408 , 2017. |
|
DOI: |
10.1155/2017/6123408 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Jatropha curcas cake, a by-product of biodiesel production, is rich in protein and has potential to be used in livestock feed; however, the presence of antinutritional factors and phorbol esters limits its use.Thus, this study investigated toxicological and reproductive effects in maleWistar rats after subchronic exposure to J. curcas cake subjected to detoxification procedures. Rats were divided into seven groups (𝑛 = 10) and treated for 60 days.The control group received commercial feed, while experimental groups received a diet containing 5% J. curcas cake nonhydrolyzed or hydrolyzed with 5MNaOH. The cakes were unwashed or washed with ethanol or water and were autoclaved at 121∘C for 30 minutes. Alkaline hydrolysis combined with ethanol washing decreased the phorbol ester concentration in the cake by 98%. Histopathological findings included diffuse degeneration of the liver and edema around the pulmonary vessels in the nonhydrolyzed groups. In addition, nontreated females mated with males of nonhydrolyzed unwashed group showed a decreased number of live fetuses and an increased placental weight. There were no signs of toxicity in rats given hydrolyzed cakes washed and unwashed, indicating that alkaline hydrolysis associated with heat treatment is an efficient method for detoxification of the J. curcas cake. |
|
Palavras-Chave: |
Efeitos reprodutivos; Efeitos toxicológicos; Exposição subcrônica; Ratos machoWistar. |
|
Thesagro: |
Desintoxicação; Jatropha Curcas. |
|
Categoria do assunto: |
-- |
|
Marc: |
LEADER 02317naa a2200301 a 4500
001 2071980
005 2018-01-12
008 2017 bl uuuu u00u1 u #d
024 7 $a10.1155/2017/6123408$2DOI
100 1 $aMOURA, L. T. S.
245 $aHistopathological and Reproductive Evaluation in Male Rats Fed Jatropha curcas Seed Cake with or without Alkaline Hydrolysis and Subjected to Heat Treatment.$h[electronic resource]
260 $c2017
520 $aJatropha curcas cake, a by-product of biodiesel production, is rich in protein and has potential to be used in livestock feed; however, the presence of antinutritional factors and phorbol esters limits its use.Thus, this study investigated toxicological and reproductive effects in maleWistar rats after subchronic exposure to J. curcas cake subjected to detoxification procedures. Rats were divided into seven groups (𝑛 = 10) and treated for 60 days.The control group received commercial feed, while experimental groups received a diet containing 5% J. curcas cake nonhydrolyzed or hydrolyzed with 5MNaOH. The cakes were unwashed or washed with ethanol or water and were autoclaved at 121∘C for 30 minutes. Alkaline hydrolysis combined with ethanol washing decreased the phorbol ester concentration in the cake by 98%. Histopathological findings included diffuse degeneration of the liver and edema around the pulmonary vessels in the nonhydrolyzed groups. In addition, nontreated females mated with males of nonhydrolyzed unwashed group showed a decreased number of live fetuses and an increased placental weight. There were no signs of toxicity in rats given hydrolyzed cakes washed and unwashed, indicating that alkaline hydrolysis associated with heat treatment is an efficient method for detoxification of the J. curcas cake.
650 $aDesintoxicação
650 $aJatropha Curcas
653 $aEfeitos reprodutivos
653 $aEfeitos toxicológicos
653 $aExposição subcrônica
653 $aRatos machoWistar
700 1 $aSOUZA, D. P. M.
700 1 $aMENDONCA, S.
700 1 $aRIBEIRO, J. A. de A.
700 1 $aSOUSA, L. F.
700 1 $aRAMOS, A. T.
700 1 $aMAIORKA, P. C.
700 1 $aARAÚJO, V. L.
700 1 $aMARUO, V. M.
773 $tBioMed Research International$gv. 2017, artigo 6123408 , 2017.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Agroenergia (CNPAE) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 58 | |
| 5. |  | ALVES, E. J. Estabelecimento do bananal. Cruz das Almas: Embrapa Mandioca e Fruticultura, 2001. 2 p. (Embrapa Mandioca e Fruticultura. Banana em Foco, 23)| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
|   |
| Registros recuperados : 58 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
