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| Registros recuperados : 133 | |
| 101. |  | COLOMBO, G. de S.; MENDES, I. V.; SOUTO, B. de M.; PARACHIN, N.; ALMEIDA, J. R. M. de; QUIRINO, B. F. Descoberta de novos genes de xilose isomerase em rúmen de cabras brasileiras, In: ENCONTRO DE PESQUISA E INOVAÇÃO DA EMBRAPA AGROENERGIA, 4.,2017, Brasília, DF. Anais... Brasília, DF: Embrapa, 2017. p. 16-21.| Biblioteca(s): Embrapa Agroenergia. |
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| 102. | | ALMEIDA, J. R. M. de; VIEIRA, W. B.; PIRES, C. S. S.; SUJII, E. R; SCHIMIDT, F. G. V.; BORGES, M.; ZARBIN, P. H. G. Desenvolvimento de armadilhas com feromônio sexual para o monitoramento do complexo de percevejos da soja. In: WORKSHOP DO TALENTO ESTUDANTIL DA EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA, 4., 1999, Brasília. Anais: resumos dos trabalhos. Brasília, DF: EMBRAPA-CENARGEN, 1999. p. 125.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 103. | | SOARES, C. E. V. F.; MACHADO, B. R. C.; PACHECO, T. F.; FRANCO, P. F.; GONCALVES, S. B.; ALMEIDA, J. R. M. de. New microbial strains for production of fuels and chemicals from lignocellulose. In: SYMPOSIUM ON BIOTECHNOLOGY FOR FUELS AND CHEMICALS, 38., 2016, Baltimore, MD. [Abstracts ...]. Fairfax: Society for Industrial Microbiology and Biotechnology, 2016. Não paginado.| Biblioteca(s): Embrapa Agroenergia. |
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| 104. | | ALMEIDA, J. R. M. de; WIMAN, M.; HEER, D.; BRINK, D. P.; SAUER, U.; HAHN‐HÄGERDAL, B.; LIDÉN, G.; GORWA‐GRAUSLUND, M. F. Physiological and molecular characterization of yeast cultures pre-adapted for fermentation of lignocellulosic hydrolysate. Fermentation, v. 9, n. 72, p. 2-21, 2023.| Biblioteca(s): Embrapa Agroenergia. |
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| 105. | | CAMPOS, C. G.; VERAS, H. C. T.; RIBEIRO, J. A. de A.; COSTA, P. P. K. G.; RODRIGUES, C. M.; ALMEIDA, J. R. M. de; ABDELNUR, P. V. Preparo de amostra em metabolômica de leveduras para a determinação dos metabólitos produzidos na fermentação de xilose. In: ENCONTRO DE PESQUISA E INOVAÇÃO DA EMBRAPA AGROENERGIA, 2., 2015, Brasília, DF. Anais ... Brasília, DF: Embrapa Agroenergia, 2015. p. 81-83| Biblioteca(s): Embrapa Agroenergia. |
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| 106. | | ROMERO PELÁEZ, R. D.; WISCHRAL, D.; CUNHA, J. R. B.; MENDES, T. D.; PACHECO, T. F.; SIQUEIRA, F. G. de; ALMEIDA, J. R. M. de. Production of enzymatic extract with high cellulolytic and oxidative activities by co-culture of Trichoderma reesei and Panus lecomtei. Fermentation, v. 8, n. 10, 522, 2022. 17 p.| Biblioteca(s): Embrapa Agroenergia. |
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| 107. | | FRANCO, P. F.; LIMA, L. M.; POLETTO, C. M.; MENDES, T. D.; SALUM, T. F. C.; FAVARO, L. C. de L.; ALMEIDA, J. R. M. de. Prospecção e melhoramento de microrganismos para produção de etanol lignocelulósico. In: CONGRESSO BRASILEIRO DE RECURSOS GENÉTICOS, 2., 2012, Belém, PA. Anais... Brasília, DF: SBRG; Manaus: Embrapa Amazônia Ocidental, 2012. Não paginado.| Biblioteca(s): Embrapa Agroenergia. |
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| 108. | | LACERDA, V. A. M. L.; SOUSA, G. P. de; ROSINHA, G. M. S.; RECH FILHO, E. L.; ALMEIDA, J. R. M. de; BITTENCOURT, D. M. de C. Comparativo metodológico na produção de espidroínas sintéticas de aranhas da biodiversidade brasileira em bactérias. In: ENCONTRO DE PESQUISA E INOVAÇÃO DA EMBRAPA AGROENERGIA, 7., 2023, Brasília, DF. Anais... Brasília, DF: Embrapa, 2023. p. 88-92.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 109. | | LACERDA, V. A. M. L.; SOUSA, G. P. de; ROSINHA, G. M. S.; RECH FILHO, E. L.; ALMEIDA, J. R. M. de; BITTENCOURT, D. M. de C. Comparativo metodológico na produção de espidroínas sintéticas de aranhas da biodiversidade brasileira em bactérias. In: ENCONTRO DE PESQUISA E INOVAÇÃO DA EMBRAPA AGROENERGIA, 7., 2023, Brasília, DF. Anais... Brasília, DF: Embrapa, 2023. p. 88-92.| Biblioteca(s): Embrapa Agroenergia. |
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| 110. | | ABDELNUR, P. V.; CAMPOS, C.; RIBEIRO, J. A. de A.; COSTA, P. P. K. G.; VERAS, H.; RODRIGUES, C. M.; PARACHIN, N.; ALMEIDA, J. R. M. de. Comparative metabolomics of xylose-fermenting yeasts by UHPLC-MS/MS: effects of oxygen levels on fermentation performance. In: ANNUAL CONFERENCE OF THE METABOLOMICS SOCIETY, 13., 2017, Brisbane, Austrália. Conference abstracts. [S.l.]: Metabolomics Society, 2017. p. 72.| Biblioteca(s): Embrapa Agroenergia. |
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| 112. | | SOUSA, G. P. de; SOUSA, G. P. de; LACERDA, V. A. M.; ROSINHA, G. M. S.; RECH FILHO, E. L.; SOUTO, B. de M.; QUIRINO, B. F.; ALMEIDA, J. R. M. de; BITTENCOURT, D. M. de C. Modelagem e produção de espidroína sintética de seda de aranha para aplicações biomédicas. In: ENCONTRO DE PESQUISA E INOVAÇÃO DA EMBRAPA AGROENERGIA, 7., 2023, Brasília, DF. Anais... Brasília, DF : Embrapa, 2023. p. 153.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 113. | | SOUSA, G. P. de; SOUSA, G. P. de; LACERDA, V. A. M.; ROSINHA, G. M. S.; RECH FILHO, E. L.; SOUTO, B. de M.; QUIRINO, B. F.; ALMEIDA, J. R. M. de; BITTENCOURT, D. M. de C. Modelagem e produção de espidroína sintética de seda de aranha para aplicações biomédicas. In: ENCONTRO DE PESQUISA E INOVAÇÃO DA EMBRAPA AGROENERGIA, 7., 2023, Brasília, DF. Anais... Brasília, DF : Embrapa, 2023. p. 153.| Biblioteca(s): Embrapa Agroenergia. |
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| 114. | | CAMPOS, C. G.; RIBEIRO, J. A. de A.; COSTA, P. P. K. G.; PEREIRA, K. A.; VERAS, H. C.; ALMEIDA, J. R. M. de; RODRIGUES, C. M.; ABDELNUR, P. V. Análise quantitativa dos metabólitos produzidos por levedura na via de fermentação da xilose utilizando UHPLC-MS/MS. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE QUÍMICA, 39., 2016, Goiânia, GO. Criar e empreender: anais ... São Paulo: SBQ, 2016. Não paginado.| Biblioteca(s): Embrapa Agroenergia. |
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| 115. | | PEREIRA. C. B.; SILVA, R. M. C.; POLETTO, C. M.; ARAÚJO, K. P.; RIBEIRO, J. A. de A.; RODRIGUES, C. M.; ABDELNUR, P. V.; ALMEIDA, J. R. M. de; DAMASO, M. C. T. Seleção de fungos filamentosos para produção de polióis a partir da bioconversão de glicerina bruta. In: SIMPÓSIO NACIONAL DE BIOPROCESSOS, 20.; SIMPÓSIO DE HIDRÓLISE ENZIMÁTICA DE BIOMASSA, 11., 2015, Fortaleza, CE. [Anais ...]. São Paulo: Associação Brasileira de Engenharia Química, 2015.| Biblioteca(s): Embrapa Agroenergia. |
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| 116. | | PEREIRA, C. B.; SILVA, R. M. C. da; POLETTO, C. M.; CAMPOS, C. G.; RIBEIRO, J. A. de A.; RODRIGUES, C. M.; ABDELNUR, P. V.; ALMEIDA, J. R. M. de; DAMASO, M. C. T. Screening of microorganisms for production of aggregated-value chemicals from glycerin bioconversion. In: SYMPOSIUM ON BIOTECHNOLOGY FOR FUELS AND CHEMICALS, 37., 2015, San Diego, California. [Resumos ...] Fairfax: Society for Industrial Microbiology and Biotechnology, 2015.| Biblioteca(s): Embrapa Agroenergia. |
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| 117. | | CAMPOS, C. G.; RIBEIRO, J. A. de A.; VERAS, H. C. T.; COSTA, P. P. K. G.; ARAÚJO, K. P.; ALMEIDA, J. R. M. de; RODRIGUES, C. M.; ABDELNUR, P. V. Identificação de alvos moleculares na via metabólica de fermentação de xilose utilizando estratégias de metabolômica. In: WORKSHOP DA PÓS-GRADUAÇÃO EM QUÍMICA, 1., 2015, Goiânia, GO. [Resumos ...] Goiânia: UFG, 2015. WSPGQ-027| Biblioteca(s): Embrapa Agroenergia. |
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| 118. | | COLOMBO, G. DE S.; MENDES, I. V.; SOUTO, B. de M.; BARRETO, C. C.; SERRA, L. A.; NORONA, E. F.; PARACHIN, N. S.; ALMEIDA, J. R. M. de; QUIRINO, B. F. Identification and functional expression of a new xylose isomerase from the goat rumen microbiome in Saccharomyces cerevisiae. Letters in Applied Microbiology, 2022.| Biblioteca(s): Embrapa Agroenergia. |
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| 119. | | TORRES, N. A. M.; ANDRADE, T. M. G. de; SOUSA, T. D. de; DUARTE-BRANDÃO, L. T.; NAKAI, D. K.; TRICHEZ, D.; CARNEIRO, C. V. G. C.; REIS, V. C. B.; ALMEIDA, J. R. M. de. Engenharia metabólica para a produção de etileno glicol por Komagataella phaffii a partir de hidrolisados de biomassa. In: ENCONTRO DE PESQUISA E INOVAÇÃO DA EMBRAPA AGROENERGIA, 7., 2023, Brasília, DF. Anais... Brasília, DF : Embrapa, 2023. p. 24.| Biblioteca(s): Embrapa Agroenergia. |
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| 120. | | HERRERA, C. R. J.; VIEIRA, V. R.; BENOLIEL, T.; CARNEIRO, C. V. G. C.; MARCO, J. L. de; MORAES, L. M. P. de; ALMEIDA, J. R. M. de; TORRES, F. A. G. Engineering Zymomonas mobilis for the Production of Xylonic Acid from Sugarcane Bagasse Hydrolysate. Microorganisms, v. 9, 1372, 2021.| Biblioteca(s): Embrapa Agroenergia. |
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| Registros recuperados : 133 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Agroenergia. |
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Data corrente: |
18/01/2023 |
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Data da última atualização: |
25/10/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 3 |
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Autoria: |
ALMEIDA, J. R. M. de; WIMAN, M.; HEER, D.; BRINK, D. P.; SAUER, U.; HAHN‐HÄGERDAL, B.; LIDÉN, G.; GORWA‐GRAUSLUND, M. F. |
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Afiliação: |
JOAO RICARDO MOREIRA DE ALMEIDA, CNPAE; MAGNUS WIMAN, LUND UNIVERSITY; DOMINIK HEER, INSTITUTE OF MOLECULAR SYSTEMS BIOLOGY; DANIEL P. BRINK, LUND UNIVERSITY; UWE SAUER, INSTITUTE OF MOLECULAR SYSTEMS BIOLOGY; BÄRBEL HAHN‐HÄGERDAL, LUND UNIVERSITY; GUNNAR LIDÉN, LUND UNIVERSITY; MARIE F. GORWA‐GRAUSLUND, LUND UNIVERSITY. |
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Título: |
Physiological and molecular characterization of yeast cultures pre-adapted for fermentation of lignocellulosic hydrolysate. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
Fermentation, v. 9, n. 72, p. 2-21, 2023. |
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DOI: |
https://doi.org/10.3390/fermentation9010072 |
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Idioma: |
Inglês |
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Conteúdo: |
Economically feasible bioethanol process from lignocellulose requires efficient fermentation by yeast of all sugars present in the hydrolysate. However, when exposed to lignocellulosic hydrolysate, Saccharomyces cerevisiae is challenged with a variety of inhibitors that reduce yeast viability, growth, and fermentation rate, and in addition damage cellular structures. In order to evaluate the capability of S. cerevisiae to adapt and respond to lignocellulosic hydrolysates, the physiological effect of cultivating yeast in the spruce hydrolysate was comprehensively studied by assessment of yeast performance in simultaneous saccharification and fermentation (SSF), measurement of furaldehyde reduction activity, assessment of conversion of phenolic compounds and genome‐wide transcription analysis. The yeast cultivated in spruce hydrolysate developed a rapid adaptive response to lignocellulosic hydrolysate, which significantly improved its fermentation performance in subsequent SSF experiments. The adaptation was shown to involve the induction of NADPHdependent aldehyde reductases and conversion of phenolic compounds during the fed‐batch cultivation. These properties were correlated to the expression of several genes encoding oxidoreductases, notably AAD4, ADH6, OYE2/3, and YML131w. The other most significant transcriptional changes involved genes involved in transport mechanisms, such as YHK8, FLR1, or ATR1. A large set of genes were found to be associated with transcription factors (TFs) involved in stress response (Msn2p, Msn4p, Yap1p) but also cell growth and division (Gcr4p, Ste12p, Sok2p), and these TFs were most likely controlling the response at the post‐transcriptional level. MenosEconomically feasible bioethanol process from lignocellulose requires efficient fermentation by yeast of all sugars present in the hydrolysate. However, when exposed to lignocellulosic hydrolysate, Saccharomyces cerevisiae is challenged with a variety of inhibitors that reduce yeast viability, growth, and fermentation rate, and in addition damage cellular structures. In order to evaluate the capability of S. cerevisiae to adapt and respond to lignocellulosic hydrolysates, the physiological effect of cultivating yeast in the spruce hydrolysate was comprehensively studied by assessment of yeast performance in simultaneous saccharification and fermentation (SSF), measurement of furaldehyde reduction activity, assessment of conversion of phenolic compounds and genome‐wide transcription analysis. The yeast cultivated in spruce hydrolysate developed a rapid adaptive response to lignocellulosic hydrolysate, which significantly improved its fermentation performance in subsequent SSF experiments. The adaptation was shown to involve the induction of NADPHdependent aldehyde reductases and conversion of phenolic compounds during the fed‐batch cultivation. These properties were correlated to the expression of several genes encoding oxidoreductases, notably AAD4, ADH6, OYE2/3, and YML131w. The other most significant transcriptional changes involved genes involved in transport mechanisms, such as YHK8, FLR1, or ATR1. A large set of genes were found to be associated with transcr... Mostrar Tudo |
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Thesaurus NAL: |
Industrial microbiology; Lignocellulose; Microarray technology; Phenolic compounds; Transcriptomics. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1151045/1/Physiological-and-molecular.pdf
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Marc: |
LEADER 02594naa a2200277 a 4500
001 2151045
005 2023-10-25
008 2023 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.3390/fermentation9010072$2DOI
100 1 $aALMEIDA, J. R. M. de
245 $aPhysiological and molecular characterization of yeast cultures pre-adapted for fermentation of lignocellulosic hydrolysate.$h[electronic resource]
260 $c2023
520 $aEconomically feasible bioethanol process from lignocellulose requires efficient fermentation by yeast of all sugars present in the hydrolysate. However, when exposed to lignocellulosic hydrolysate, Saccharomyces cerevisiae is challenged with a variety of inhibitors that reduce yeast viability, growth, and fermentation rate, and in addition damage cellular structures. In order to evaluate the capability of S. cerevisiae to adapt and respond to lignocellulosic hydrolysates, the physiological effect of cultivating yeast in the spruce hydrolysate was comprehensively studied by assessment of yeast performance in simultaneous saccharification and fermentation (SSF), measurement of furaldehyde reduction activity, assessment of conversion of phenolic compounds and genome‐wide transcription analysis. The yeast cultivated in spruce hydrolysate developed a rapid adaptive response to lignocellulosic hydrolysate, which significantly improved its fermentation performance in subsequent SSF experiments. The adaptation was shown to involve the induction of NADPHdependent aldehyde reductases and conversion of phenolic compounds during the fed‐batch cultivation. These properties were correlated to the expression of several genes encoding oxidoreductases, notably AAD4, ADH6, OYE2/3, and YML131w. The other most significant transcriptional changes involved genes involved in transport mechanisms, such as YHK8, FLR1, or ATR1. A large set of genes were found to be associated with transcription factors (TFs) involved in stress response (Msn2p, Msn4p, Yap1p) but also cell growth and division (Gcr4p, Ste12p, Sok2p), and these TFs were most likely controlling the response at the post‐transcriptional level.
650 $aIndustrial microbiology
650 $aLignocellulose
650 $aMicroarray technology
650 $aPhenolic compounds
650 $aTranscriptomics
700 1 $aWIMAN, M.
700 1 $aHEER, D.
700 1 $aBRINK, D. P.
700 1 $aSAUER, U.
700 1 $aHAHN‐HÄGERDAL, B.
700 1 $aLIDÉN, G.
700 1 $aGORWA‐GRAUSLUND, M. F.
773 $tFermentation$gv. 9, n. 72, p. 2-21, 2023.
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