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Registros recuperados : 22 | |
2. | | PARK, Y. K.; ALENCAR, S. M.; SCAMPARINI, A. R. P.; AGUIAR, C. L. Própolis produzida no sul do Brasil, Argentina e Uruguai: evidências fitoquímicas de sua origem vegetal. Ciência Rural, Santa Maria, RS, v. 32, n. 6, p. 997-1003, nov./dez. 2002. Biblioteca(s): Embrapa Florestas. |
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5. | | PARK, Y. K.; AGUIAR, C. L.; ALENCAR, S. M.; MASCARENHAS, H. A. A.; SCAMPARINI, A. R. P. Conversão de malonil - B- glicosil isoflavonas em isoflavonas glicosiladas presentes em alguns cultivares de soja brasileira. Ciência e Tecnologia de Alimentos, Campinas, v. 22, n. 2, p. 105-109, maio-ago. 2002. Biblioteca(s): Embrapa Soja. |
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6. | | PARK, Y. K.; AGUIAR, C. L.; ALENCAR, S. M.; MASCARENHAS, H. A. A.; SCAMPARINI, A. R. P. Avaliação do teor de isoflavonas em soja brasileira. Ciencia y Tecnologia Alimentaria, Ourense, España, v. 3, n. 3, p. 156-160, 2001. Biblioteca(s): Embrapa Soja. |
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7. | | RODRIGUES, G. H.; SUSIN, I.; PIRES, A. V.; ALENCAR, S. M. de; MENDES, C. Q.; GENTIL, R. S. Perfil de ácidos graxos e composição química do músculo longissimus dorsi de cordeiros alimentados com dietas contendo polpa cítrica. Revista Brasileira de Zootecnia, v. 39, n. 6, p. 1346-1352, 2010. Biblioteca(s): Embrapa Caprinos e Ovinos. |
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9. | | SOUZA, E. H. de; MASSARIOLI, A.; MORENO, I. A. M.; ALENCAR, S. M. de; SOUZA, F. V. D.; MARTINELLI, A. P. Quantificação e composição do néctar em bromeliaceae. In: CONGRESSO BRASILEIRO DE RECURSOS GENÉTICOS, 2., 2012, Belém, PA. Anais... Brasília, DF: Sociedade Brasileira de Recursos Genéticos, 2012. 1 CD-ROM. Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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11. | | MELO, P. S.; BERGAMASCHI, K. B.; TIVERON, A. P.; MASSARIOLI, A. P.; OLDONI, T. L. C.; ZANUS, M. C.; PEREIRA, G. E.; ALENCAR, S. M. de. Composição fenólica e atividade antioxidante de resíduos agroindustriais. Ciência Rural, Santa Maria, v. 41, n. 6, p. 1088-1093, jun. 2011. Biblioteca(s): Embrapa Semiárido; Embrapa Uva e Vinho. |
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12. | | MASSARIOLI, A. P.; SARTORI, A. G. de O.; JULIANO, F. F.; SANTOS, R. C. dos; RAMOS, J. P. C.; LIMA, L. M. de L.; ALENCAR, S. M. de. Optimizing procedures for antioxidant phenolics extraction from skin and kernel of peanuts with contrasting levels of drought tolerance. Foods, v. 11, n. 3, 449, p. 2-14, 2022. Biblioteca(s): Embrapa Algodão. |
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13. | | CAMARGO, A. C. de; BIASOTO, A. C. T.; SCHWEMBER, A. R.; GRANADO, D.; RASERA, G. B.; FRANCHIN, M.; ROSALEN, P. L.; ALENCAR, S. M.; SHAHIDI, F. Should we ban total phenolics and antioxidant screening methods? The link between antioxidant potential and activation of NF-KB using phenolic compounds from grape by-products. Food Chemistry, v. 290, p. 229-238, 2019. Biblioteca(s): Embrapa Semiárido. |
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15. | | SOUZA, E. H. de; MASSARIOLI, A.; MORENO, I. A. M.; SOUZA, F. V. D.; LEDO, C. A. da S.; ALENCAR, S. M.; MARTINELLI, A. P. Volatile compounds profile of bromeliaceae flowers. Revista de Biologia Tropical, v. 64, n. 3, p. 1101-1116, September, 2016. 0034-7744 Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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16. | | CAMPESTRINI, L. H.; RASERA, G. B.; CAMARGO, A. C. de; FRANCHIN, M.; NANI, B. D.; ROSALEN, P. L.; CANNIATTI-BRAZACA, S. G.; BIASOTO, A. C. T.; SHAHIDIC, F.; ALENCAR, S. M. Alkaline conditions better extract anti-inflammatory polysaccharides from winemaking by-products. Food Research International, v. 131, may 2020. Biblioteca(s): Embrapa Semiárido. |
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17. | | DENNY, C.; LAZARINI, J. G.; FRANCHIN, M.; MELO, P. S.; PEREIRA, G. E.; MASSARIOLI, A. P.; MORENO, I. A. M.; PASCHOAL, J. A. R.; ALENCAR, S. M.; ROSALEN, P. L. Bioprospection of Petit Verdot grape pomace as a source of anti-inflammatory compounds Journal of Functional Foods, v. 8, p. 292-300, 2014. Biblioteca(s): Embrapa Semiárido; Embrapa Uva e Vinho. |
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18. | | MASSARIOLI, A. P.; SARTORI, A. G. de O.; JULIANO, F. F.; AMARAL, J. E. P. G. do; SANTOS, R. C. dos; LIMA, L. M. de; ALENCAR, S. M. de. Simulated gastrointestinal digestion/Caco-2 cell model to predict bioaccessibility and intestinal permeability of p-coumaric acid and p-coumaroyl derivatives in peanut. Food Chemistry, v. 400, 134036, p. 1-8, 2023. Biblioteca(s): Embrapa Algodão. |
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19. | | MELO, P. S.; MASSARIOLI, A. P.; DENNY, C.; SANTOS, L. F. dos; FRANCHIN, M.; PEREIRA, G. E.; VIEIRA, T. M. F. de S.; ROSALEN, P. L.; ALENCAR, S. M. de. Winery by-products: extraction optimization, phenolic composition and cytotoxic evaluation to act as a new source of scavenging of reactive oxygen species. Food Chemistry, v. 181, p. 160-169, Aug. 2015. Biblioteca(s): Embrapa Semiárido; Embrapa Uva e Vinho. |
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20. | | ALMEIDA, V. V.; SILVA, J. P. M.; SCHINCKEL, A. P.; MEIRA, A. N.; MOREIRA, G. C. M.; GOMES, J. D.; POLETI, M. D.; DARGELIO, M. D. B.; PATINHO, I.; CONTRERAS-CASTILLO, C. J.; COUTINHO, L. L.; MOURÃO, G. B.; REECY, J. M.; KOLTES, D.; SERÃO, N. V. L.; REGITANO, L. C. de A.; FUKUMASU, H.; BRUSTOLINI, A. P. L.; ALENCAR, S. M.; LUCHIARI FILHO, A.; CESAR, A. S. M. Effects of increasing dietary oil inclusion from different sources on growth performance, carcass and meat quality traits, and fatty acid profile in genetically lean immunocastrated male pigs. Livestock Science, v.248, jun. 2021, 104515. 10 p. Biblioteca(s): Embrapa Pecuária Sudeste. |
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Registros recuperados : 22 | |
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Registro Completo
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
Data corrente: |
01/09/2022 |
Data da última atualização: |
01/09/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
FANALLI, S. L.; SILVA, B. P. M. DA; GOMES, J. D.; CICONELLO, F. N.; ALMEIDA, V. V. DE; FREITAS, F. A. O.; MOREIRA, G. C. M.; VIGNATO, B. S.; AFONSO, J.; REECY, J.; KOLTES, J.; KOLTES, D.; REGITANO, L. C. de A.; BAILEIRO, J. C. DE C.; FREITAS, L.; COUTINHO, L. L.; FUKUMASU, H.; ALENCAR, S. M. DE; LUCHIARI FILHO, A.; CESAR, A. S. M. |
Afiliação: |
SIMARA LARISSA FANALLI, University of São Paulo; BRUNA PEREIRA MARTINS DA SILVA, University of São Paulo; JULIA DEZEN GOMES, University of São Paulo; FERNANDA NERY CICONELLO, University of São Paulo; VIVIAN VEZZONI DE ALMEIDA, Federal University of Goiás; FELIPE ANDRÉ OLIVEIRA FREITAS, University of São Paulo; GABRIEL COSTA MONTEIRO MOREIRA, University of Liège; BÁRBARA SILVA-VIGNATO, University of São Paulo; JULIANA AFONSO, University Federal of São Carlos; JAMES REECY, Iowa State University; JAMES KOLTES, Iowa State University; DAWN KOLTES, Iowa State University; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; JÚLIO CESAR DE CARVALHO BAILEIRO, University of São Paulo; LUCIANA FREITAS, DB Genética de Suínos; LUIZ LEHMANN COUTINHO, University of São Paulo; HEIDGE FUKUMASU, University of São Paulo; SEVERINO MATIAS DE ALENCAR, University of São Paulo; ALBINO LUCHIARI FILHO, University of São Paulo; ALINE SILVA MELLO CESAR, University of São Paulo. |
Título: |
Effect of dietary soybean oil inclusion on liver-related transcription factors in a pig model for metabolic diseases. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Scientific Reports, v. 12, 10318, jun. 2022. |
Páginas: |
10 p. |
DOI: |
https://doi.org/10.1038/s41598-022-14069-1 |
Idioma: |
Inglês |
Conteúdo: |
Dietary fatty acids (FA) are components of the lipids, which contribute to membrane structure, energy input, and biological functions related to cellular signaling and transcriptome regulation. However, the consumers still associate dietary FA with fat deposition and increased occurrence of metabolic diseases such as obesity and atherosclerosis. Previous studies already demonstrated that some fatty acids are linked with inflammatory response, preventing metabolic diseases. To better understand the role of dietary FA on metabolic diseases, for the first time, a study to identify key transcription factors (TF) involved in lipid metabolism and inflammatory response by transcriptome analysis from liver samples of animal models was performed. The key TF were identified by functional enrichment analysis from the list of differentially expressed genes identified in liver samples between 35 pigs fed with 1.5% or 3.0% soybean oil. The functional enrichment analysis detected TF linked to lipid homeostasis and inflammatory response, such as RXRA, EGFR, and SREBP2 precursor. These findings demonstrated that key TF related to lipid metabolism could be modulated by dietary inclusion of soybean oil. It could contribute to nutrigenomics research field that aims to elucidate dietary interventions in animal and human health, as well as to drive food technology and science. |
Palavras-Chave: |
Dietary FA on metabolic diseases; Dietary fatty acids; Dietary interventions; Human metabolic diseases; Lipid homeostasis; Transcriptome profile of animal models. |
Thesaurus NAL: |
Lipid metabolism; Nutrigenomics. |
Categoria do assunto: |
Q Alimentos e Nutrição Humana |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1145965/1/EffectDietarySoybean.pdf
|
Marc: |
LEADER 02791naa a2200469 a 4500 001 2145965 005 2022-09-01 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1038/s41598-022-14069-1$2DOI 100 1 $aFANALLI, S. L. 245 $aEffect of dietary soybean oil inclusion on liver-related transcription factors in a pig model for metabolic diseases.$h[electronic resource] 260 $c2022 300 $a10 p. 520 $aDietary fatty acids (FA) are components of the lipids, which contribute to membrane structure, energy input, and biological functions related to cellular signaling and transcriptome regulation. However, the consumers still associate dietary FA with fat deposition and increased occurrence of metabolic diseases such as obesity and atherosclerosis. Previous studies already demonstrated that some fatty acids are linked with inflammatory response, preventing metabolic diseases. To better understand the role of dietary FA on metabolic diseases, for the first time, a study to identify key transcription factors (TF) involved in lipid metabolism and inflammatory response by transcriptome analysis from liver samples of animal models was performed. The key TF were identified by functional enrichment analysis from the list of differentially expressed genes identified in liver samples between 35 pigs fed with 1.5% or 3.0% soybean oil. The functional enrichment analysis detected TF linked to lipid homeostasis and inflammatory response, such as RXRA, EGFR, and SREBP2 precursor. These findings demonstrated that key TF related to lipid metabolism could be modulated by dietary inclusion of soybean oil. It could contribute to nutrigenomics research field that aims to elucidate dietary interventions in animal and human health, as well as to drive food technology and science. 650 $aLipid metabolism 650 $aNutrigenomics 653 $aDietary FA on metabolic diseases 653 $aDietary fatty acids 653 $aDietary interventions 653 $aHuman metabolic diseases 653 $aLipid homeostasis 653 $aTranscriptome profile of animal models 700 1 $aSILVA, B. P. M. DA 700 1 $aGOMES, J. D. 700 1 $aCICONELLO, F. N. 700 1 $aALMEIDA, V. V. DE 700 1 $aFREITAS, F. A. O. 700 1 $aMOREIRA, G. C. M. 700 1 $aVIGNATO, B. S. 700 1 $aAFONSO, J. 700 1 $aREECY, J. 700 1 $aKOLTES, J. 700 1 $aKOLTES, D. 700 1 $aREGITANO, L. C. de A. 700 1 $aBAILEIRO, J. C. DE C. 700 1 $aFREITAS, L. 700 1 $aCOUTINHO, L. L. 700 1 $aFUKUMASU, H. 700 1 $aALENCAR, S. M. DE 700 1 $aLUCHIARI FILHO, A. 700 1 $aCESAR, A. S. M. 773 $tScientific Reports$gv. 12, 10318, jun. 2022.
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Embrapa Pecuária Sudeste (CPPSE) |
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