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 | Acesso ao texto completo restrito à biblioteca da Embrapa Semiárido. Para informações adicionais entre em contato com cpatsa.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Semiárido. |
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Data corrente: |
09/01/2015 |
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Data da última atualização: |
22/06/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
BRITTO, D. de; MOURA, M. R de; AOUADA, F. A.; PINOLA, F. G.; LUNDSTEDT, L. M.; ASSIS, O. B. G. de; MATTOSO, L. H. C. |
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Afiliação: |
DOUGLAS DE BRITTO, CPATSA; MARCIA R. DE MOURA, UNESP, Ilha Solteira; FAUZE A. AOUADA, UNESP, Ilha Solteira; FLÁVIA G. PINOLA; LICIA MARIA LUNDSTEDT, CNPASA; ODILIO BENEDITO GARRIDO DE ASSIS, CNPDIA; LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA. |
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Título: |
Entrapment characteristics of hydrosoluble vitamins loaded into chitosan and N,N,N-Trimethyl chitosan nanoparticles. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
Macromolecular Research, v. 22, n. 12, p. 1261-1267, 2014. |
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DOI: |
DOI 10.1007/s13233-014-2176-9 |
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Idioma: |
Inglês |
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Conteúdo: |
Nanoencapsulation is a process suitable for use in reducing degradation of instable components. In this study, chitosan and trimethyl chitosan with tripolyphosphate were used to nanoencapsulate vitamins C, B9, and B12. Analysis of the particle size showed that for a fix proportion of the polymer tripolyphosphate, the system showed a wide variation in size with the amount of added vitamins: e.g., for vitamin B9, the particle size varied from 150±5 nm to 809±150 nm. The zeta potential confirmed that trimethyl chitosan nanoparticles generally had a lower net positive charge (20 mV) than chitosan nanoparticles (40 mV). The encapsulation efficiency was found to be dependent on nanoparticle structure and vitamin solubility, with vitamin B9 the most efficiently encapsulated (approximately 40%). UV-Visible spectroscopy indicated different release profiles for vitamins C, B9, and B12 in a neutral PBS solution with release rates of 36%, 52%, and 16% after 2, 24, and 4 h, respectively. In conclusion the liberation was found to be slower in acidic media. |
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Palavras-Chave: |
Encapsulamento; Fishery diet; Libertação controlada; Nanoencapsulação; Nanotecnologia; Quitosana; Trimetil. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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Marc: |
LEADER 01942naa a2200289 a 4500
001 2004933
005 2017-06-22
008 2014 bl uuuu u00u1 u #d
024 7 $aDOI 10.1007/s13233-014-2176-9$2DOI
100 1 $aBRITTO, D. de
245 $aEntrapment characteristics of hydrosoluble vitamins loaded into chitosan and N,N,N-Trimethyl chitosan nanoparticles.$h[electronic resource]
260 $c2014
520 $aNanoencapsulation is a process suitable for use in reducing degradation of instable components. In this study, chitosan and trimethyl chitosan with tripolyphosphate were used to nanoencapsulate vitamins C, B9, and B12. Analysis of the particle size showed that for a fix proportion of the polymer tripolyphosphate, the system showed a wide variation in size with the amount of added vitamins: e.g., for vitamin B9, the particle size varied from 150±5 nm to 809±150 nm. The zeta potential confirmed that trimethyl chitosan nanoparticles generally had a lower net positive charge (20 mV) than chitosan nanoparticles (40 mV). The encapsulation efficiency was found to be dependent on nanoparticle structure and vitamin solubility, with vitamin B9 the most efficiently encapsulated (approximately 40%). UV-Visible spectroscopy indicated different release profiles for vitamins C, B9, and B12 in a neutral PBS solution with release rates of 36%, 52%, and 16% after 2, 24, and 4 h, respectively. In conclusion the liberation was found to be slower in acidic media.
653 $aEncapsulamento
653 $aFishery diet
653 $aLibertação controlada
653 $aNanoencapsulação
653 $aNanotecnologia
653 $aQuitosana
653 $aTrimetil
700 1 $aMOURA, M. R de
700 1 $aAOUADA, F. A.
700 1 $aPINOLA, F. G.
700 1 $aLUNDSTEDT, L. M.
700 1 $aASSIS, O. B. G. de
700 1 $aMATTOSO, L. H. C.
773 $tMacromolecular Research$gv. 22, n. 12, p. 1261-1267, 2014.
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