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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Corte. |
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Data corrente: |
08/01/2025 |
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Data da última atualização: |
08/01/2025 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
SOUZA, C. B.; MENEZES, G. R. de O.; GONDO, A.; EGITO, A. A. do; RAMOS, P. V. B.; GOMES, R. da C.; RIBAS, M. N.; FERNANDES JUNIOR, J. A.; GUIMARÃES, S. E. F. |
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Afiliação: |
CHRISTHIAN B. SOUZA, UNIVERSIDADE FEDERAL DE VIÇOSA; GILBERTO ROMEIRO DE OLIVEIRA MENEZE, CNPGC; ANDREA GONDO, CNPGC; ANDREA ALVES DO EGITO, CNPGC; PEDRO V. B. RAMOS, AMERICAN ANGUS ASSOCIATION; RODRIGO DA COSTA GOMES, CNPGC; MARCELO NEVES RIBAS, PONTA AGRO; JOSÉ ANTÔNIO FERNANDES JUNIOR, GRAMA SENEPOL; SIMONE ELIZA FACIONI GUIMARÃES, UNIVERSIDADE FEDERAL DE VIÇOSA. |
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Título: |
Estimation of genetic parameters and GWAS on water efficiency traits in the Senepol cattle. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
Journal of Animal Breeding and Genetics, 2024. |
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ISSN: |
0931-2668 |
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DOI: |
https://doi.org/10.1111/jbg.12920 |
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Idioma: |
Inglês |
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Notas: |
Online ahead of print. |
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Conteúdo: |
ABSTRACT - The need for producing in environmentally resilient system drives new research to achieve sustainable beef production. Water footprint of the beef supply chain is a concern that must be addressed, aiming to improve water use within the production chain. One approach is genetic selection of beef cattle for water efficiency. However, it is essential to understand the genetic architecture and mechanisms involved in the expression of this phenotype to choose the best selection criteria. Thus, our study aimed to estimate genetic parameters for water efficiency traits, conduct a genome-wide association study (GWAS) and identify the genetic networks and biological processes involved. A population of 1762 purebred Senepol cattle was phenotyped for the following water efficiency traits: water intake (WI), gross water efficiency (GWE), water conversion ratio (WCR), residual water intake based on average daily gain (RWIADG) and residual water intake based on dry matter intake (RWIDMI). A subset of 1342 animals was genotyped using GGP Bovine 50 K SNP Chip with (734 animals) or 100 K (508 animals), and imputation from 50K to 100K was performed with Beagle software. The heritability estimates were 0.36±0.06, 0.26±0.05, 0.22±0.05, 0.24±0.05 and 0.20±0.05 for WI, GWE, WCR, RWIADG and RWIDMI, respectively. Unlike the raw measures of WI, the phenotypic correlations between average daily gain (ADG) and the residuals (RWIDMI and RWIADG) were zero. All water efficiency traits were moderately to highly correlated with each other. GWAS were used to estimate the effect of 79,860 single nucleotide polymorphisms (SNPs), and significant SNPs were only observed for WCR. Enrichment analysis of genes in the significant regions revealed the involvement of different biological processes, such as saliva production, water transport, renal system and immune system. Genetic selection of Senepol cattle for water efficiency traits is feasible and can reduce water requirements for meat production. Water efficiency measures are polygenic traits, and different biological processes act simultaneously on the expression of related phenotypes. MenosABSTRACT - The need for producing in environmentally resilient system drives new research to achieve sustainable beef production. Water footprint of the beef supply chain is a concern that must be addressed, aiming to improve water use within the production chain. One approach is genetic selection of beef cattle for water efficiency. However, it is essential to understand the genetic architecture and mechanisms involved in the expression of this phenotype to choose the best selection criteria. Thus, our study aimed to estimate genetic parameters for water efficiency traits, conduct a genome-wide association study (GWAS) and identify the genetic networks and biological processes involved. A population of 1762 purebred Senepol cattle was phenotyped for the following water efficiency traits: water intake (WI), gross water efficiency (GWE), water conversion ratio (WCR), residual water intake based on average daily gain (RWIADG) and residual water intake based on dry matter intake (RWIDMI). A subset of 1342 animals was genotyped using GGP Bovine 50 K SNP Chip with (734 animals) or 100 K (508 animals), and imputation from 50K to 100K was performed with Beagle software. The heritability estimates were 0.36±0.06, 0.26±0.05, 0.22±0.05, 0.24±0.05 and 0.20±0.05 for WI, GWE, WCR, RWIADG and RWIDMI, respectively. Unlike the raw measures of WI, the phenotypic correlations between average daily gain (ADG) and the residuals (RWIDMI and RWIADG) were zero. All water efficiency traits were mod... Mostrar Tudo |
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Thesagro: |
Bovino; Gado de Corte; Melhoramento Genético Animal; Nutrição Animal; Produção de Carne; Seleção Genética. |
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Thesaurus Nal: |
Animal breeding; Senepol. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 03181naa a2200349 a 4500
001 2171282
005 2025-01-08
008 2024 bl uuuu u00u1 u #d
022 $a0931-2668
024 7 $ahttps://doi.org/10.1111/jbg.12920$2DOI
100 1 $aSOUZA, C. B.
245 $aEstimation of genetic parameters and GWAS on water efficiency traits in the Senepol cattle.$h[electronic resource]
260 $c2024
500 $aOnline ahead of print.
520 $aABSTRACT - The need for producing in environmentally resilient system drives new research to achieve sustainable beef production. Water footprint of the beef supply chain is a concern that must be addressed, aiming to improve water use within the production chain. One approach is genetic selection of beef cattle for water efficiency. However, it is essential to understand the genetic architecture and mechanisms involved in the expression of this phenotype to choose the best selection criteria. Thus, our study aimed to estimate genetic parameters for water efficiency traits, conduct a genome-wide association study (GWAS) and identify the genetic networks and biological processes involved. A population of 1762 purebred Senepol cattle was phenotyped for the following water efficiency traits: water intake (WI), gross water efficiency (GWE), water conversion ratio (WCR), residual water intake based on average daily gain (RWIADG) and residual water intake based on dry matter intake (RWIDMI). A subset of 1342 animals was genotyped using GGP Bovine 50 K SNP Chip with (734 animals) or 100 K (508 animals), and imputation from 50K to 100K was performed with Beagle software. The heritability estimates were 0.36±0.06, 0.26±0.05, 0.22±0.05, 0.24±0.05 and 0.20±0.05 for WI, GWE, WCR, RWIADG and RWIDMI, respectively. Unlike the raw measures of WI, the phenotypic correlations between average daily gain (ADG) and the residuals (RWIDMI and RWIADG) were zero. All water efficiency traits were moderately to highly correlated with each other. GWAS were used to estimate the effect of 79,860 single nucleotide polymorphisms (SNPs), and significant SNPs were only observed for WCR. Enrichment analysis of genes in the significant regions revealed the involvement of different biological processes, such as saliva production, water transport, renal system and immune system. Genetic selection of Senepol cattle for water efficiency traits is feasible and can reduce water requirements for meat production. Water efficiency measures are polygenic traits, and different biological processes act simultaneously on the expression of related phenotypes.
650 $aAnimal breeding
650 $aSenepol
650 $aBovino
650 $aGado de Corte
650 $aMelhoramento Genético Animal
650 $aNutrição Animal
650 $aProdução de Carne
650 $aSeleção Genética
700 1 $aMENEZES, G. R. de O.
700 1 $aGONDO, A.
700 1 $aEGITO, A. A. do
700 1 $aRAMOS, P. V. B.
700 1 $aGOMES, R. da C.
700 1 $aRIBAS, M. N.
700 1 $aFERNANDES JUNIOR, J. A.
700 1 $aGUIMARÃES, S. E. F.
773 $tJournal of Animal Breeding and Genetics, 2024.
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Registro original: |
Embrapa Gado de Corte (CNPGC) |
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