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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
29/03/2023 |
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Autoria: |
HOHENBOKEN, W. D.; MUGGLI, N. E.; BERGGREN-THOMAS, P. L.; NORMAN, L. M. |
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Afiliação: |
Oregon State University, USA. |
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Título: |
Inheritance of active and passive humoral immunity in ruminants. |
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Ano de publicação: |
1986 |
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Fonte/Imprenta: |
Proceedings New Zealand Society of Animal Production, v. 46, p. 5-14, 1986. |
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Idioma: |
Inglês |
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Conteúdo: |
The active immune system involves phagocytic, cell mediated and humoral processes plus complement proteins, all interacting to protect the individual from pathogenic organisms. Passive immunity is acquired by newborn ungulates by ingestion of immunoglobulins from colostrum. Research in laboratory animals has established that peak antibody synthesis following challenge with a foreign antigen responds readily to directional selection. The increased titre frequently results in enhanced resistance to some diseases but enhanced susceptibility to others. Oregon State University research has produced conflicting results as to the heritability ofthe ability of newborn calves and lambs to acquire and absorb colostral immunoglobulins and as to the heritability of this passive immunity considered asa trait of the dam. Significant differences among breeds, selection lines and strains did exist for level of colostral immunoglobulins, and low levelstand, in oneexperiment, high levelsas well) wereassociated with lowerneonatal survival. In cattle, there was little evidence that either active immune response or level of complement protein C3 was heritable; but in ewes, the antibody titre to a challenge antigen was moderately to highly heritable. The authors speculate that stabilising selection for immune system traits might be most effective to improvegeneralised disease resistanceand overall livestock production efficiency. |
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Palavras-Chave: |
Sistema imunologico; Traits. |
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Thesagro: |
Bovino; Doença Animal; Ovino; Resistência. |
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Thesaurus Nal: |
Active immunity; Cattle diseases; Disease resistance; Humoral immunity; Immunoglobulins; Immunological synapse; Passive immunity; Sheep diseases. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 02350naa a2200325 a 4500
001 1520728
005 2023-03-29
008 1986 bl uuuu u00u1 u #d
100 1 $aHOHENBOKEN, W. D.
245 $aInheritance of active and passive humoral immunity in ruminants.$h[electronic resource]
260 $c1986
520 $aThe active immune system involves phagocytic, cell mediated and humoral processes plus complement proteins, all interacting to protect the individual from pathogenic organisms. Passive immunity is acquired by newborn ungulates by ingestion of immunoglobulins from colostrum. Research in laboratory animals has established that peak antibody synthesis following challenge with a foreign antigen responds readily to directional selection. The increased titre frequently results in enhanced resistance to some diseases but enhanced susceptibility to others. Oregon State University research has produced conflicting results as to the heritability ofthe ability of newborn calves and lambs to acquire and absorb colostral immunoglobulins and as to the heritability of this passive immunity considered asa trait of the dam. Significant differences among breeds, selection lines and strains did exist for level of colostral immunoglobulins, and low levelstand, in oneexperiment, high levelsas well) wereassociated with lowerneonatal survival. In cattle, there was little evidence that either active immune response or level of complement protein C3 was heritable; but in ewes, the antibody titre to a challenge antigen was moderately to highly heritable. The authors speculate that stabilising selection for immune system traits might be most effective to improvegeneralised disease resistanceand overall livestock production efficiency.
650 $aActive immunity
650 $aCattle diseases
650 $aDisease resistance
650 $aHumoral immunity
650 $aImmunoglobulins
650 $aImmunological synapse
650 $aPassive immunity
650 $aSheep diseases
650 $aBovino
650 $aDoença Animal
650 $aOvino
650 $aResistência
653 $aSistema imunologico
653 $aTraits
700 1 $aMUGGLI, N. E.
700 1 $aBERGGREN-THOMAS, P. L.
700 1 $aNORMAN, L. M.
773 $tProceedings New Zealand Society of Animal Production$gv. 46, p. 5-14, 1986.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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