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 | Acesso ao texto completo restrito à biblioteca da Embrapa Amazônia Ocidental. Para informações adicionais entre em contato com cpaa.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Amazônia Ocidental. |
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Data corrente: |
14/03/2017 |
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Data da última atualização: |
29/03/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
SOARES, B. V.; NEVES, L. R.; FERREIRA, D. O.; OLIVEIRA, M. S. B.; CHAVES, F. C. M.; CHAGAS, E. C.; GONÇALVES, R. A.; TAVARES-DIAS, M. |
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Afiliação: |
BRUNA VIANA SOARES, UNIFAP; LIGIA RIGÔR NEVES, EMBRAPA AMAPÁ; DRIELLY OLIVEIRA FERREIRA, EMBRAPA AMAPÁ; MARCOS SIDNEY BRITO OLIVEIRA, UFOPA; FRANCISCO CELIO MAIA CHAVES, CPAA; EDSANDRA CAMPOS CHAGAS, CPAA; RAISSA ALVES GONÇALVES, INPA; MARCOS TAVARES-DIAS, CPAF-AP. |
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Título: |
Antiparasitic activity, histopathology and physiology of Colossoma macropomum (tambaqui) exposed to the essential oil of Lippia sidoides (Verbenaceae). |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Veterinary Parasitology, v. 234, p. 49-56, Jan. 2017. |
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DOI: |
http://dx.doi.org/10.1016/j.vetpar.2016.12.012 |
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Idioma: |
Português |
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Conteúdo: |
In vivo and in vitro antiparasitic activity of the essential oil of Lippia sidoides and blood and histological alterations were assessed in Colossoma macropomum (tambaqui). Essential oil concentrations of 10, 20, 40, 80, 160 and 320 mg/L were assayed in vitro against monogenoideans Anacanthorus spathulatus, Notozothecium janauachensis and Mymarothecium boegeri from fish gills. Lippia sidoides essential oil concentrations of 320 and 160 mg/L were 100% effective against monogenoideans in 10 min and 1 h of exposure, respectively. However, the effectiveness of 100% concentrations of 80 mg/L and 40 mg/L occurred in 3 and 6 h, respectively. In the in vivo tests, juvenile fish were submitted to 60 min of baths with 10 mg/L and 15 min of baths with 20 mg/L of the essential oil of L. sidoides. These therapeutic baths were not efficient against Ichthyophthirius multifiliis, and monogenoideans present in the gills of C. macropomum. In addition, 10 and 20 mg/L of the essential oil of L. sidoides caused an anesthetic effect on the fish and did not influence total glucose and protein plasma levels; however, it decreased the number of total erythrocytes in fish exposed to the higher concentration of this essential oil. Severe alterations and irreversible damage were observed in the fish gills just after L. sidoides essential oil baths and after 24 h of recovery. The most recurrent lesions found were hyperplasia and fusion of the lamellar epithelium, vasodilation, detachment of the gill epithelium and lamellar aneurism, epithelial breakdown with hemorrhage, congestion, edema and necrosis, proliferation of the mucous cells and chloride cells and lamellar hypertrophy. Therefore, since the essential oil of L. sidoides has in vitro antiparasitic activity and low concentrations of it have shown toxic effects, the bioactive potential of its main chemical components should be investigated, as well as more efficient forms of its administration in therapeutic baths in order to eliminate fish parasites. MenosIn vivo and in vitro antiparasitic activity of the essential oil of Lippia sidoides and blood and histological alterations were assessed in Colossoma macropomum (tambaqui). Essential oil concentrations of 10, 20, 40, 80, 160 and 320 mg/L were assayed in vitro against monogenoideans Anacanthorus spathulatus, Notozothecium janauachensis and Mymarothecium boegeri from fish gills. Lippia sidoides essential oil concentrations of 320 and 160 mg/L were 100% effective against monogenoideans in 10 min and 1 h of exposure, respectively. However, the effectiveness of 100% concentrations of 80 mg/L and 40 mg/L occurred in 3 and 6 h, respectively. In the in vivo tests, juvenile fish were submitted to 60 min of baths with 10 mg/L and 15 min of baths with 20 mg/L of the essential oil of L. sidoides. These therapeutic baths were not efficient against Ichthyophthirius multifiliis, and monogenoideans present in the gills of C. macropomum. In addition, 10 and 20 mg/L of the essential oil of L. sidoides caused an anesthetic effect on the fish and did not influence total glucose and protein plasma levels; however, it decreased the number of total erythrocytes in fish exposed to the higher concentration of this essential oil. Severe alterations and irreversible damage were observed in the fish gills just after L. sidoides essential oil baths and after 24 h of recovery. The most recurrent lesions found were hyperplasia and fusion of the lamellar epithelium, vasodilation, detachment of the gill epi... Mostrar Tudo |
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Palavras-Chave: |
Medicinal plant; Parasite; Planta medicina. |
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Thesagro: |
Parasito; Peixe de água doce; Sangue. |
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Thesaurus Nal: |
Blood; Freshwater fish. |
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Categoria do assunto: |
S Ciências Biológicas |
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Marc: |
LEADER 02984naa a2200313 a 4500
001 2067004
005 2017-03-29
008 2017 bl --- 0-- u #d
024 7 $ahttp://dx.doi.org/10.1016/j.vetpar.2016.12.012$2DOI
100 1 $aSOARES, B. V.
245 $aAntiparasitic activity, histopathology and physiology of Colossoma macropomum (tambaqui) exposed to the essential oil of Lippia sidoides (Verbenaceae).$h[electronic resource]
260 $c2017
520 $aIn vivo and in vitro antiparasitic activity of the essential oil of Lippia sidoides and blood and histological alterations were assessed in Colossoma macropomum (tambaqui). Essential oil concentrations of 10, 20, 40, 80, 160 and 320 mg/L were assayed in vitro against monogenoideans Anacanthorus spathulatus, Notozothecium janauachensis and Mymarothecium boegeri from fish gills. Lippia sidoides essential oil concentrations of 320 and 160 mg/L were 100% effective against monogenoideans in 10 min and 1 h of exposure, respectively. However, the effectiveness of 100% concentrations of 80 mg/L and 40 mg/L occurred in 3 and 6 h, respectively. In the in vivo tests, juvenile fish were submitted to 60 min of baths with 10 mg/L and 15 min of baths with 20 mg/L of the essential oil of L. sidoides. These therapeutic baths were not efficient against Ichthyophthirius multifiliis, and monogenoideans present in the gills of C. macropomum. In addition, 10 and 20 mg/L of the essential oil of L. sidoides caused an anesthetic effect on the fish and did not influence total glucose and protein plasma levels; however, it decreased the number of total erythrocytes in fish exposed to the higher concentration of this essential oil. Severe alterations and irreversible damage were observed in the fish gills just after L. sidoides essential oil baths and after 24 h of recovery. The most recurrent lesions found were hyperplasia and fusion of the lamellar epithelium, vasodilation, detachment of the gill epithelium and lamellar aneurism, epithelial breakdown with hemorrhage, congestion, edema and necrosis, proliferation of the mucous cells and chloride cells and lamellar hypertrophy. Therefore, since the essential oil of L. sidoides has in vitro antiparasitic activity and low concentrations of it have shown toxic effects, the bioactive potential of its main chemical components should be investigated, as well as more efficient forms of its administration in therapeutic baths in order to eliminate fish parasites.
650 $aBlood
650 $aFreshwater fish
650 $aParasito
650 $aPeixe de água doce
650 $aSangue
653 $aMedicinal plant
653 $aParasite
653 $aPlanta medicina
700 1 $aNEVES, L. R.
700 1 $aFERREIRA, D. O.
700 1 $aOLIVEIRA, M. S. B.
700 1 $aCHAVES, F. C. M.
700 1 $aCHAGAS, E. C.
700 1 $aGONÇALVES, R. A.
700 1 $aTAVARES-DIAS, M.
773 $tVeterinary Parasitology$gv. 234, p. 49-56, Jan. 2017.
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Registro original: |
Embrapa Amazônia Ocidental (CPAA) |
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Registro Completo
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Biblioteca(s): |
Embrapa Milho e Sorgo. |
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Data corrente: |
10/11/2011 |
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Data da última atualização: |
28/05/2018 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
FASSINI, P. G.; NODA, R. W.; FERREIRA, E. S.; SILVA, M. A.; NEVES, V. A.; DEMONTE, A. |
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Afiliação: |
ROBERTO WILLIANS NODA, CNPMS. |
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Título: |
Soybean glycinin improves HDL-C and suppresses the effects of rosuvastatin on hypercholesterolemic rats. |
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Ano de publicação: |
2011 |
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Fonte/Imprenta: |
Lipids in Health and Disease, v. 10, n. 165, 2011. |
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Idioma: |
Inglês |
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Conteúdo: |
Background: This study was an investigation of the effects of ingesting a daily dose of isolated glycinin soy protein (11S globulin), in association with rosuvastatin, on the control of hypercholesterolemia in experimental animals. Methods: Male Wistar rats were kept in individual cages under appropriate controlled conditions of temperature, light and humidity. The animals were divided into five groups (n = 9): 1) standard (STD): fed on casein as protein source; 2) hypercholesterolemic (HC): STD plus 1% cholesterol and 0.5% cholic acid; 3) HC+11S: hypercholesterolemic + glycinin (300 mg/kg/day); 4) HC+ROS: hypercholesterolemic + rosuvastatin (10 mg/kg/day); 5) HC+11S+ROS: HC diet, the 11S protein and the drug in the doses given in (3) and (4). The protein and the drug were administered by gavage for 28 days. The results indicated that the addition of 1% cholesterol and 0.5% cholic acid induced hypercholesterolemia in the animals without interfering with their weight gain. Results: A single daily dose of glycinin contributed an additional 2.8% of dietary protein intake and demonstrated its functional role, particularly in raising HDL-C, decreasing triglycerides in the liver and improving the atherogenic index in animals exposed to a hypercholesterolemic diet. Conclusion: Most of the beneficial effects of the isolated treatments disappeared when the drug (rosuvastatin) and the protein (glycinin) were taken simultaneously. The association was shown not to interact additively, as noted in the plasma levels of total cholesterol and non-HDL cholesterol, and in the significant increase of cholesterol in the liver. Studies are in progress to identify the effects of peptides derived from the 11S globulin and their role in cholesterol metabolism. MenosBackground: This study was an investigation of the effects of ingesting a daily dose of isolated glycinin soy protein (11S globulin), in association with rosuvastatin, on the control of hypercholesterolemia in experimental animals. Methods: Male Wistar rats were kept in individual cages under appropriate controlled conditions of temperature, light and humidity. The animals were divided into five groups (n = 9): 1) standard (STD): fed on casein as protein source; 2) hypercholesterolemic (HC): STD plus 1% cholesterol and 0.5% cholic acid; 3) HC+11S: hypercholesterolemic + glycinin (300 mg/kg/day); 4) HC+ROS: hypercholesterolemic + rosuvastatin (10 mg/kg/day); 5) HC+11S+ROS: HC diet, the 11S protein and the drug in the doses given in (3) and (4). The protein and the drug were administered by gavage for 28 days. The results indicated that the addition of 1% cholesterol and 0.5% cholic acid induced hypercholesterolemia in the animals without interfering with their weight gain. Results: A single daily dose of glycinin contributed an additional 2.8% of dietary protein intake and demonstrated its functional role, particularly in raising HDL-C, decreasing triglycerides in the liver and improving the atherogenic index in animals exposed to a hypercholesterolemic diet. Conclusion: Most of the beneficial effects of the isolated treatments disappeared when the drug (rosuvastatin) and the protein (glycinin) were taken simultaneously. The association was shown not to interact additively, a... Mostrar Tudo |
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Thesagro: |
Soja. |
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Categoria do assunto: |
F Plantas e Produtos de Origem Vegetal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/46059/1/Soybean-glycinin.pdf
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Marc: |
LEADER 02335naa a2200193 a 4500
001 1905555
005 2018-05-28
008 2011 bl uuuu u00u1 u #d
100 1 $aFASSINI, P. G.
245 $aSoybean glycinin improves HDL-C and suppresses the effects of rosuvastatin on hypercholesterolemic rats.$h[electronic resource]
260 $c2011
520 $aBackground: This study was an investigation of the effects of ingesting a daily dose of isolated glycinin soy protein (11S globulin), in association with rosuvastatin, on the control of hypercholesterolemia in experimental animals. Methods: Male Wistar rats were kept in individual cages under appropriate controlled conditions of temperature, light and humidity. The animals were divided into five groups (n = 9): 1) standard (STD): fed on casein as protein source; 2) hypercholesterolemic (HC): STD plus 1% cholesterol and 0.5% cholic acid; 3) HC+11S: hypercholesterolemic + glycinin (300 mg/kg/day); 4) HC+ROS: hypercholesterolemic + rosuvastatin (10 mg/kg/day); 5) HC+11S+ROS: HC diet, the 11S protein and the drug in the doses given in (3) and (4). The protein and the drug were administered by gavage for 28 days. The results indicated that the addition of 1% cholesterol and 0.5% cholic acid induced hypercholesterolemia in the animals without interfering with their weight gain. Results: A single daily dose of glycinin contributed an additional 2.8% of dietary protein intake and demonstrated its functional role, particularly in raising HDL-C, decreasing triglycerides in the liver and improving the atherogenic index in animals exposed to a hypercholesterolemic diet. Conclusion: Most of the beneficial effects of the isolated treatments disappeared when the drug (rosuvastatin) and the protein (glycinin) were taken simultaneously. The association was shown not to interact additively, as noted in the plasma levels of total cholesterol and non-HDL cholesterol, and in the significant increase of cholesterol in the liver. Studies are in progress to identify the effects of peptides derived from the 11S globulin and their role in cholesterol metabolism.
650 $aSoja
700 1 $aNODA, R. W.
700 1 $aFERREIRA, E. S.
700 1 $aSILVA, M. A.
700 1 $aNEVES, V. A.
700 1 $aDEMONTE, A.
773 $tLipids in Health and Disease$gv. 10, n. 165, 2011.
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Embrapa Milho e Sorgo (CNPMS) |
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