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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
06/11/2002 |
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Data da última atualização: |
06/11/2002 |
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Autoria: |
ADAMS, T. E.; SAKURAI, H.; ADAMS, B. M. |
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Título: |
Effect of stress-like concentrations of cortisol on estradiol-dependent expression of gonadotropin-releasing hormone receptor in orchidectomized sheep. |
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Ano de publicação: |
1999 |
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Fonte/Imprenta: |
Biology of Reproduction, v. 60, n. 1, p. 164-168, 1999. |
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Idioma: |
Inglês |
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Conteúdo: |
The effect of stress-like concentrations of cortisol (C) on estrogen-dependent expression of GnRH receptor was evaluated using orchidectomized sheep (wethers; n = 6 anímais per group). C (5.0 mg/50 kg per hour; groups 1-4) or a comparable volume of vehicle (groups 5-8) was delivered by continuous in- fusion for 48 h. During the final 24 h of infusion, anímais received concurrent infusion of estradiol (E2) at rates of O (groups 1 and 5), 0.5 (groups 2 and 6), 2.0 (groups 3 and 7), or 8.0 (groups 4 and 8) Jl.g/50 kg per hour. Pituitary tissue was collected at the end of infusion. Although C did not affect (p > 0.05) the basal concentration of GnRH receptor or GnRH receptor mRNA, it reduced (p < 0.05) the increase in receptor and receptor mRNA induced by concurrent administration of 0.5 ug E2/50 kg per hour. In contrast, the increase in GnRH receptor expression induced by higher levels of estrogen stimulation was not affected (p > 0.05) by concurrent administration of C. The effect of C on the temporal pattern of E2-depen- dent increase in GnRH receptor expression was assessed using wethers receiving E2 (0.5 Jl.g/50 kg per hour) by continuous in- fusion for O (groups 1 and 5), 24 (groups 2 and 6), 48 (groups 3 and 7), or 72 h (groups 4 and 8). Animals received C (5.0 mg/ 50 kg per hour; groups 1-4) or vehicle (groups 5-8) beginning 24 h before, and continuing throughout, the E2 delivery period. Stress-like concentrations of C reduced (p < 0.05) the increase in GnRH receptor and receptor mRNA induced after 24 h of E2 stimulation. However, the suppressive effect of C was transient, and tissue levels of GnRH receptor and receptor mRNA were comparable after 72 h of E2 infusion in anímais receiving C or vehicle alone. Collectively these observations demonstrate that C suppresses estrogen-dependent increase in tissue concentrations of GnRH receptor and receptor mRNA. However, this effect of C is transient and not evident in animals receiving moderate to high levels of estrogen stimulation. This transient suppression of GnRH receptor expression mar account, at least in part, for the anti-gonadal effect of glucocorticoids. MenosThe effect of stress-like concentrations of cortisol (C) on estrogen-dependent expression of GnRH receptor was evaluated using orchidectomized sheep (wethers; n = 6 anímais per group). C (5.0 mg/50 kg per hour; groups 1-4) or a comparable volume of vehicle (groups 5-8) was delivered by continuous in- fusion for 48 h. During the final 24 h of infusion, anímais received concurrent infusion of estradiol (E2) at rates of O (groups 1 and 5), 0.5 (groups 2 and 6), 2.0 (groups 3 and 7), or 8.0 (groups 4 and 8) Jl.g/50 kg per hour. Pituitary tissue was collected at the end of infusion. Although C did not affect (p > 0.05) the basal concentration of GnRH receptor or GnRH receptor mRNA, it reduced (p < 0.05) the increase in receptor and receptor mRNA induced by concurrent administration of 0.5 ug E2/50 kg per hour. In contrast, the increase in GnRH receptor expression induced by higher levels of estrogen stimulation was not affected (p > 0.05) by concurrent administration of C. The effect of C on the temporal pattern of E2-depen- dent increase in GnRH receptor expression was assessed using wethers receiving E2 (0.5 Jl.g/50 kg per hour) by continuous in- fusion for O (groups 1 and 5), 24 (groups 2 and 6), 48 (groups 3 and 7), or 72 h (groups 4 and 8). Animals received C (5.0 mg/ 50 kg per hour; groups 1-4) or vehicle (groups 5-8) beginning 24 h before, and continuing throughout, the E2 delivery period. Stress-like concentrations of C reduced (p < 0.05) the increase in GnRH receptor and... Mostrar Tudo |
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Palavras-Chave: |
Gonadotropina; Receptor. |
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Thesagro: |
Estradiol; Hormônio; Ovino; Stress. |
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Thesaurus Nal: |
cortisol. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02823naa a2200229 a 4500
001 1528814
005 2002-11-06
008 1999 bl uuuu u00u1 u #d
100 1 $aADAMS, T. E.
245 $aEffect of stress-like concentrations of cortisol on estradiol-dependent expression of gonadotropin-releasing hormone receptor in orchidectomized sheep.
260 $c1999
520 $aThe effect of stress-like concentrations of cortisol (C) on estrogen-dependent expression of GnRH receptor was evaluated using orchidectomized sheep (wethers; n = 6 anímais per group). C (5.0 mg/50 kg per hour; groups 1-4) or a comparable volume of vehicle (groups 5-8) was delivered by continuous in- fusion for 48 h. During the final 24 h of infusion, anímais received concurrent infusion of estradiol (E2) at rates of O (groups 1 and 5), 0.5 (groups 2 and 6), 2.0 (groups 3 and 7), or 8.0 (groups 4 and 8) Jl.g/50 kg per hour. Pituitary tissue was collected at the end of infusion. Although C did not affect (p > 0.05) the basal concentration of GnRH receptor or GnRH receptor mRNA, it reduced (p < 0.05) the increase in receptor and receptor mRNA induced by concurrent administration of 0.5 ug E2/50 kg per hour. In contrast, the increase in GnRH receptor expression induced by higher levels of estrogen stimulation was not affected (p > 0.05) by concurrent administration of C. The effect of C on the temporal pattern of E2-depen- dent increase in GnRH receptor expression was assessed using wethers receiving E2 (0.5 Jl.g/50 kg per hour) by continuous in- fusion for O (groups 1 and 5), 24 (groups 2 and 6), 48 (groups 3 and 7), or 72 h (groups 4 and 8). Animals received C (5.0 mg/ 50 kg per hour; groups 1-4) or vehicle (groups 5-8) beginning 24 h before, and continuing throughout, the E2 delivery period. Stress-like concentrations of C reduced (p < 0.05) the increase in GnRH receptor and receptor mRNA induced after 24 h of E2 stimulation. However, the suppressive effect of C was transient, and tissue levels of GnRH receptor and receptor mRNA were comparable after 72 h of E2 infusion in anímais receiving C or vehicle alone. Collectively these observations demonstrate that C suppresses estrogen-dependent increase in tissue concentrations of GnRH receptor and receptor mRNA. However, this effect of C is transient and not evident in animals receiving moderate to high levels of estrogen stimulation. This transient suppression of GnRH receptor expression mar account, at least in part, for the anti-gonadal effect of glucocorticoids.
650 $acortisol
650 $aEstradiol
650 $aHormônio
650 $aOvino
650 $aStress
653 $aGonadotropina
653 $aReceptor
700 1 $aSAKURAI, H.
700 1 $aADAMS, B. M.
773 $tBiology of Reproduction$gv. 60, n. 1, p. 164-168, 1999.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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| Registros recuperados : 36 | |
| 2. |  | BOTIN, A. A.; BALDONI, A. B.; TARDIN, F. D.; HOOGERHEIDE, E. S. S.; TONINI, H. Classificação de castanheiras-do-brasil (Bertholletia excelsa) com base em características morfológicas na amazônia matogrossense. In: CONGRESSO BRASILEIRO DE RECURSOS GENÉTICOS, 3., 2014, Santos, SP. Resumos... Brasília, DF: Sociedade Brasileira de Recursos Genéticos, 2014.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agrossilvipastoril; Embrapa Milho e Sorgo. |
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| 4. | | BALDONI, A. B.; TONINI, H.; TARDIN, F. D.; BOTELHO, S. C. C.; TEODORO, P. E. Minimum number of measurements for evaluating Bertholletia excelsa. Genetics and Molecular Research, Ribeirão Preto, v. 16, n. 3, p. 1-10, 2017. Artigo - gmr16039783.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Agrossilvipastoril; Embrapa Milho e Sorgo. |
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| 7. | | GIUSTINA, L. D.; BALDONI, A. B.; GREGOLIN, F. S.; TARDIN, F. D.; TONINI, H.; TEODORO, P. E.; NEVES, L. G. Agrupamento de progênies de diferentes matrizes de castanheira-do-Brasil quanto a germinação e desenvolvimento inicial. Revista Científica Intelletto, Venda Nova do Imigrante, ES, v. 2, n. 2, p. 35-44, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 5 |
| Biblioteca(s): Embrapa Agrossilvipastoril; Embrapa Milho e Sorgo. |
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| 9. | | RIBEIRO, L. P.; TARDIN, F. D.; MENEZES, C. B. de; BALDONI, A. B.; TEODORO, P. E.; BHERING, L. L. Combining yield, earliness and plant height in a single genotype: a proposal for breeding in grain sorghum (Sorghum bicolor L.). Revista de la Facultad de Ciencias Agrarias UNCuyo, v. 53, n. 1, p. 11-21, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
| Biblioteca(s): Embrapa Agrossilvipastoril; Embrapa Milho e Sorgo. |
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| 10. | | SPONCHIADO, S.; TARDIN, F. D.; FERREIRA, L. U.; MENEZES, C. B. de; BALDONI, A. B.; TEODORO, P. E. Seleção de híbridos de sorgo mais produtivos com o uso de modelos mistos em Sinop, MT. In: ENCONTRO DE CIÊNCIA E TECNOLOGIAS AGROSSUSTENTÁVEIS; JORNADA CIENTÍFICA DA EMBRAPA AGROSSILVIPASTORIL, 6., 2017, Sinop, MT. Resumos... Sinop, MT: Embrapa Agrossilpastoril, 2017. p. 38-40.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 11. | | SPONCHIADO, S.; TARDIN, F. D.; FERREIRA, L. U.; MENEZES, C. B. de; BALDONI, A. B.; TEODORO, P. E. Seleção de parentais para geração de híbridos de sorgo mais produtivos com o uso de modelos mistos em Sete Lagoas, MG. In: ENCONTRO DE CIÊNCIA E TECNOLOGIAS AGROSSUSTENTÁVEIS; JORNADA CIENTÍFICA DA EMBRAPA AGROSSILVIPASTORIL, 6., 2017, Sinop, MT. Resumos... Sinop, MT: Embrapa Agrossilpastoril, 2017. p. 34-37.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 12. | | BALDONI, A. B.; SILVA, A. J. R.; ROELIS, B. V.; PEREIRA, L. L.; TARDIN, F. D.; TONINI, H. Enxertia de genótipos superiores em castanheira-do-brasil para a formação de um jardim clonal. In: CONGRESSO BRASILEIRO DE MELHORAMENTO DE PLANTAS, 9., 2017, Foz do Iguaçu. Melhoramento de plantas: projetando o futuro. Foz do Iguaçu: SBMP, 2017. p. 763.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agrossilvipastoril; Embrapa Milho e Sorgo. |
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| 13. | | BOTIN, A. A.; BALDONI, A. B.; HOOGERHEIDE, E. S. S.; CAMPOS, S. de C.; TARDIN, F. D. Estrutura populacional de castanheira-do-brasil (Bertholletia excelsa H.B.K.) no município de Itaúba, Mato Grosso. In: JORNADA CIENTÍFICA DA EMBRAPA AGROSSILVIPASTORIL, 1., 2012, Sinop. Anais... Sinop: Embrapa Agrossilvipastoril, 2012.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 14. | | ROELIS, B. V.; PAIVA, G. A. de; ROVEDA, A. P.; BALDONI, A. B.; BISPO, R. B.; ROSSI, A. P. B. Meiose e viabilidade polínica de Castanheira-do-Brasil (Bertholletia excelsa Bonpl.). Research, Society and Development, v. 11, n. 8, e4111830545, 2022.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 2 |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 15. | | PARISOTTO, D. C.; TARDIN, F. D.; SPIERING, B.; SILVA, A. J. R.; NUNES, E. L.; BALDONI, A. B.; MALACARNE, A. M.; RODRIGUES, J. A. S. Avaliação de híbridos de sorgo forrageiro em segunda safra. In: CONGRESSO NACIONAL DE MILHO E SORGO, 32., 2018, Lavras. Soluções integradas para os sistemas de produção de milho e sorgo no Brasil: resumos. Sete Lagoas: Associação Brasileira de Milho e Sorgo, 2018. p. 308.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 16. | | SILVA, A. J. R.; MARQUES, J. A. de B.; SPIERING, B.; PARISOTTO, D. C.; NUNES, E. L.; TARDIN, F. D.; BALDONI, A. B. Avaliação da enxertia e desenvolvimento de enxertos no jardim clonal de castanheira-do-brasil da Embrapa Agrossilvipastoril. In: ENCONTRO DE CIÊNCIA E TECNOLOGIAS AGROSSUSTENTÁVEIS, 2.; JORNADA CIENTÍFICA DA EMBRAPA AGROSSILVIPASTORIL, 7., 2018. Sinop, MT. Resumos... Sinop, MT: Embrapa Agrossilpastoril, 2018. p. 179-182.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 17. | | BOTIN, A. A.; BALDONI, A. B.; PEREIRA, M. C.; TARDIN, F. D.; PALUDZYSZYN FILHO, E.; SILVA, A. J. R.; MARQUES, J. A. de B.; NEVES, L. G. Caracterização morfológica de sementes de paricá (Schizolobium parahyba var. amazonicum). In: ENCONTRO DE CIÊNCIA E TECNOLOGIAS AGROSSUSTENTÁVEIS, 2.; JORNADA CIENTÍFICA DA EMBRAPA AGROSSILVIPASTORIL, 7., 2018. Sinop, MT. Resumos... Sinop, MT: Embrapa Agrossilpastoril, 2018. p. 187-190.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 18. | | TARDIN, F. D.; SPONCHIADO, S.; FERREIRA, L. U.; MENEZES, C. B. de; BALDONI, A. B.; BARELLI, M. A. A.; TEODORO, P. E. Seleção de genitores para a obtenção de híbridos de sorgo granífero com alto desempenho produtivo. In: CONGRESSO BRASILEIRO DE MELHORAMENTO DE PLANTAS, 9., 2017, Foz do Iguaçu. Melhoramento de plantas: projetando o futuro. Foz do Iguaçu: SBMP, 2017. p. 429.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
| |
| 19. | | RIBEIRO, L. P.; SILVA, M. J. da; TEODORO, P. E.; BALDONI, A. B.; MENEZES, C. B. de; SCHAFFERT, R. E.; TARDIN, F. D. Selection of sorghum hybrids aiming at earliness, smaller height and high grain yield. In: SORGHUM IN THE 21st CENTURY, Cape Town, 2018. Food, feed and fuel in a rapidly changing world: abstracts. Cape Town: [s.n], 2018.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
| |
| 20. | | SOUZA, N. O. de; ALVES, R. S.; TEODORO, P. E.; SILVA, L. A. da; TARDIN, F. D.; BALDONI, A. B.; RESENDE, M. D. V. de; BHERING, L. L. Single- and multiple-trait BLUP in genetic selection of parents and hybrids of grain sorghum. Revista de la Facultad de Ciencias Agrarias Uncuyo, v. 51, n. 2, Jul./Dic. 2019.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
| Biblioteca(s): Embrapa Agrossilvipastoril; Embrapa Florestas; Embrapa Milho e Sorgo. |
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| Registros recuperados : 36 | |
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