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4. | | MOTA, R. R.; MARQUES, L. F. A.; LOPES, P. S.; RESENDE, M. D. V. de; SILVA, F. G. da. Inclusão de animais oriundos da técnica de transferência de embriões, na estimação de parâmetros genéticos de bovinos da raça Simental. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 9., 2012, João Pessoa. Trabalhos. João Pessoa: Sociedade Brasileira de Melhoramento Animal, 2012. Disponibilizado online. Biblioteca(s): Embrapa Florestas. |
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5. | | AZEVEDO, C. F.; RESENDE, M. D. V. de; SILVA, F. F. e; LOPES, P. S.; GUIMARÃES, S. E. F. Regressão via componentes independentes aplicada à seleção genômica para características de carcaça em suínos. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 48, n. 6, p. 619-626, jun. 2013. Biblioteca(s): Embrapa Florestas; Embrapa Unidades Centrais. |
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6. | | PAIVA, J. T.; RESENDE, M. D. V. de; RESENDE, R. T.; OLIVEIRA, H. R.; SILVA, H. T.; CAETANO, G. C.; LOPES, P. S.; SILVA, F. F. Epigenética: mecanismos, herança e implicações no melhoramento animal. Archivos de Zootecnia, v. 68, n. 262, p. 304-311, 2019. Biblioteca(s): Embrapa Florestas. |
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7. | | COSTA, E. V.; DINIZ, D. B.; VERONEZE, R.; RESENDE, M. D. V. de; AZEVEDO, C. F.; GUIMARÃES, S. E. F.; SILVA, F. F.; LOPES, P. S. Estimating additive and dominance variances for complex traits in pigs combining genomic and pedigree information. Genetics and Molecular Research, v. 14, n. 2, p. 6303-6311, June 2015. Biblioteca(s): Embrapa Florestas. |
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8. | | PINHEIRO, V. R.; SILVA, F. F. e; GUIMARÃES, S. E. F.; RESENDE, M. D. V. de; LOPES, P. S.; CRUZ, C. D.; AZEVEDO, C. F. Mapeamento de QTL para características de crescimento de suínos por meio de modelos de regressão aleatória. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 48, n. 2, p. 190-196, fev. 2013. Biblioteca(s): Embrapa Florestas; Embrapa Unidades Centrais. |
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9. | | COSTA, E. V.; VENTURA. H. T.; FIGUEIREDO, E. A. P. de; SILVA, F. F.; GLÓRIA, L. S.; GODINHO, R. M.; RESENDE, M. D. V. de; LOPES, P. S. Multi-trait and repeatability models for genetic evaluation of litter traits in pigs considering different farrowings. Revista Brasileira de Saúde e Produção Animal, Salvador, v. 17, n. 4, p. 666-676, 2016. Biblioteca(s): Embrapa Florestas; Embrapa Suínos e Aves. |
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10. | | VERARDO, L. L.; SILVA, F. F.; VARONA, L.; RESENDE, M. D. V. de; BASTIAANSEN, J. W. M.; LOPES, P. S.; GUIMARÃES, S. E. F. Bayesian GWAS and network analysis revealed new candidate genes for number of teats in pigs. Journal of Applied Genetics, v. 56, n. 1, p. 123-132, Feb. 2015. Biblioteca(s): Embrapa Florestas. |
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11. | | AZEVEDO, C. F.; NASCIMENTO, M.; SILVA, F. F.; RESENDE, M. D. V. de; LOPES, P. S.; GUIMARÃES, S. E. F.; GLÓRIA, L. S. Comparison of dimensionality reduction methods to predict genomic breeding values for carcass traits in pigs. Genetics and Molecular Research, Ribeirão Preto, v. 14, n. 4, p. 12217-12227, 2015. Biblioteca(s): Embrapa Florestas. |
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12. | | AZEVEDO, C. F.; SILVA, F. F. e; RESENDE, M. D. V. de; PETERNELLI, L. A.; GUIMARÃES, S. E. F.; LOPES, P. S. Quadrados mínimos parciais uni e multivariado aplicados na seleção genômica para características de carcaça em suínos. Ciência Rural, Santa Maria, RS, v. 43, n. 9, p. 1642-1649, set. 2013. Biblioteca(s): Embrapa Florestas. |
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13. | | MOTA, R. R.; MARQUES, L. F. A.; LOPES, P. S.; SILVA, L. P. da; RESENDE, M. D. V. de; TORRES, R. A. Genetic evaluation using multi-trait and random regression models in Simmental beef cattle. Genetics and Molecular Research, v. 12, n. 3, p. 2465-2480, 2013. Biblioteca(s): Embrapa Florestas. |
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14. | | SANTOS, V. S.; MARTINS FILHO, S.; RESENDE, M. D. V. de; AZEVEDO, C. F.; LOPES, P. S.; GUIMARÃES, S. E. F.; SILVA, F. F. Genomic prediction for additive and dominance effects of censored traits in pigs. Genetics and Molecular Research, v. 15, n. 4, gmr15048764, Oct. 2016. Biblioteca(s): Embrapa Florestas. |
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15. | | SANTOS, V. S.; MARTINS FILHO, S.; RESENDE, M. D. V. de; AZEVEDO, C. F.; LOPES, P. S.; GUIMARAES, S. E. F.; GLORIA, L. S.; SILVA, F. F. Genomic selection for slaughter age in pigs using the Cox frailty model. Genetics and Molecular Research, Ribeirão Preto, v. 14, n. 4, p. 12616-12627, 2015. Biblioteca(s): Embrapa Florestas. |
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16. | | JUNQUEIRA, V. S.; LOPES, P. S.; RESENDE, M. D. V. de; SILVA, F. F. e; LOURENÇO, D. A. L.; YOKOO, M. J. I.; CARDOSO, F. F. Impact of embryo transfer phenotypic records on large-scale beef cattle genetic evaluations. Revista Brasileira de Zootecnia, Viçosa, MG, v. 47, e20170033, 2018. 4 p. Biblioteca(s): Embrapa Florestas; Embrapa Pecuária Sul. |
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17. | | MOTA, R. R.; LOPES, P. S.; MARQUES, L. F. A.; SILVA, L. P. da; RESENDE, M. D. V. de; TORRES, R. de A. The influence of animals from embryo transfer on the genetic evaluation of growth in Simmental beef cattle by using multi-trait models. Genetics and Molecular Biology, v. 36, n. 1, p. 43-49, 2013. Biblioteca(s): Embrapa Florestas. |
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18. | | MOTA, R. R.; LOPES, P. S.; MARQUES, L. F. A.; SILVA, L. P.; PESSOA, M. C.; TORRES, R. A.; RESENDE, M. D. V. de. Influence of animals obtained using embryo transfer on the genetic evaluation of growth in Simmental beef cattle with random regression models. Genetics and Molecular Research, v. 12, n. 4, p. 5889-5904, 2013. Biblioteca(s): Embrapa Florestas. |
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19. | | PAIVA, J. T.; RESENDE, M. D. V. de; RESENDE, R. T.; OLIVEIRA, H. R. de; SILVA, H. T.; CAETANO, G. C.; LOPES, P. S.; SILVA, F. F. Transgenerational epigenetic variance for body weight in meat quails. Journal of Animal Breeding and Genetics, v. 135, n. 3, p. 178-185, June 2018. Biblioteca(s): Embrapa Florestas. |
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20. | | GLÓRIA, L. S.; CRUZ, C. D.; VIEIRA, R. A. M.; RESENDE, M. D. V. de; LOPES, P. S.; SIQUEIRA, O. H. G. B. D. de; SILVA, F. F. e. Accessing marker effects and heritability estimates from genome prediction by Bayesian regularized neural networks. Livestock Science, v. 191, p. 91-96, Sept. 2016. Biblioteca(s): Embrapa Florestas. |
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Registros recuperados : 28 | |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Florestas. Para informações adicionais entre em contato com cnpf.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Florestas. |
Data corrente: |
18/01/2017 |
Data da última atualização: |
18/01/2017 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 1 |
Autoria: |
GLÓRIA, L. S.; CRUZ, C. D.; VIEIRA, R. A. M.; RESENDE, M. D. V. de; LOPES, P. S.; SIQUEIRA, O. H. G. B. D. de; SILVA, F. F. e. |
Afiliação: |
Leonardo Siqueira Glória, UFV; Cosme Damião Cruz, UFV; Ricardo Augusto Mendonça Vieira, Universidade Estadual do Norte Fluminense; MARCOS DEON VILELA DE RESENDE, CNPF; Paulo Sávio Lopes, UFV; Otávio H. G. B. Dias de Siqueira, UFV; Fabyano Fonseca e Silva, UFV. |
Título: |
Accessing marker effects and heritability estimates from genome prediction by Bayesian regularized neural networks. |
Ano de publicação: |
2016 |
Fonte/Imprenta: |
Livestock Science, v. 191, p. 91-96, Sept. 2016. |
DOI: |
http://dx.doi.org/10.1016/j.livsci.2016.07.015 |
Idioma: |
Inglês |
Conteúdo: |
Recently, there is an increasing interest on semi- and non-parametric methods for genome-enabled prediction, among which the Bayesian regularized artificial neural networks (BRANN) stand. We aimed to evaluate the predictive performance of BRANN and to exploit SNP effects and heritability estimates using two different approaches (relative importance-RI, and relative contribution-RC). Additionally, we aimed also to compare BRANN with the traditional RR-BLUP and BLASSO by using simulated datasets. The simplest BRANN (net1), RR-BLUP and BLASSO methods outperformed other more parameterized BRANN (net2, net3, ? net6) in terms of predictive ability. For both simulated traits (Y1 and Y2) the net1 provided the best h2 estimates (0.33 for both, being the true h2=0.35), whereas RR-BLUP (0.18 and 0.22 for Y1 and Y2, respectively) and BLASSO (0.20 and 0.26 for Y1 and Y2, respectively) underestimated h2. The marker effects estimated from net1 (using RI and RC approaches) and RR-BLUP were similar, but the shrinkage strength was remarkable for BLASSO on both traits. For Y1, the correlation between the true fifty QTL effects and the effects estimated for the SNPs located in the same QTL positions were 0.61, 0.60, 0.60 and 0.55, for RI, RC, RR-BLUP and BLASSO; and for Y2, these correlations were 0.81, 0.81, 0.81 and 0.71, respectively. In summary, we believe that estimates of SNP effects are promising quantitative tools to bring discussions on chromosome regions contributing most effectively to the phenotype expression when using ANN for genomic predictions. MenosRecently, there is an increasing interest on semi- and non-parametric methods for genome-enabled prediction, among which the Bayesian regularized artificial neural networks (BRANN) stand. We aimed to evaluate the predictive performance of BRANN and to exploit SNP effects and heritability estimates using two different approaches (relative importance-RI, and relative contribution-RC). Additionally, we aimed also to compare BRANN with the traditional RR-BLUP and BLASSO by using simulated datasets. The simplest BRANN (net1), RR-BLUP and BLASSO methods outperformed other more parameterized BRANN (net2, net3, ? net6) in terms of predictive ability. For both simulated traits (Y1 and Y2) the net1 provided the best h2 estimates (0.33 for both, being the true h2=0.35), whereas RR-BLUP (0.18 and 0.22 for Y1 and Y2, respectively) and BLASSO (0.20 and 0.26 for Y1 and Y2, respectively) underestimated h2. The marker effects estimated from net1 (using RI and RC approaches) and RR-BLUP were similar, but the shrinkage strength was remarkable for BLASSO on both traits. For Y1, the correlation between the true fifty QTL effects and the effects estimated for the SNPs located in the same QTL positions were 0.61, 0.60, 0.60 and 0.55, for RI, RC, RR-BLUP and BLASSO; and for Y2, these correlations were 0.81, 0.81, 0.81 and 0.71, respectively. In summary, we believe that estimates of SNP effects are promising quantitative tools to bring discussions on chromosome regions contributing most effectively ... Mostrar Tudo |
Palavras-Chave: |
Genetic parameters; QTL; Redes neurais. |
Thesagro: |
Parâmetro Genético. |
Thesaurus NAL: |
Marker-assisted selection; Neural networks. |
Categoria do assunto: |
G Melhoramento Genético |
Marc: |
LEADER 02443naa a2200277 a 4500 001 2061138 005 2017-01-18 008 2016 bl uuuu u00u1 u #d 024 7 $ahttp://dx.doi.org/10.1016/j.livsci.2016.07.015$2DOI 100 1 $aGLÓRIA, L. S. 245 $aAccessing marker effects and heritability estimates from genome prediction by Bayesian regularized neural networks.$h[electronic resource] 260 $c2016 520 $aRecently, there is an increasing interest on semi- and non-parametric methods for genome-enabled prediction, among which the Bayesian regularized artificial neural networks (BRANN) stand. We aimed to evaluate the predictive performance of BRANN and to exploit SNP effects and heritability estimates using two different approaches (relative importance-RI, and relative contribution-RC). Additionally, we aimed also to compare BRANN with the traditional RR-BLUP and BLASSO by using simulated datasets. The simplest BRANN (net1), RR-BLUP and BLASSO methods outperformed other more parameterized BRANN (net2, net3, ? net6) in terms of predictive ability. For both simulated traits (Y1 and Y2) the net1 provided the best h2 estimates (0.33 for both, being the true h2=0.35), whereas RR-BLUP (0.18 and 0.22 for Y1 and Y2, respectively) and BLASSO (0.20 and 0.26 for Y1 and Y2, respectively) underestimated h2. The marker effects estimated from net1 (using RI and RC approaches) and RR-BLUP were similar, but the shrinkage strength was remarkable for BLASSO on both traits. For Y1, the correlation between the true fifty QTL effects and the effects estimated for the SNPs located in the same QTL positions were 0.61, 0.60, 0.60 and 0.55, for RI, RC, RR-BLUP and BLASSO; and for Y2, these correlations were 0.81, 0.81, 0.81 and 0.71, respectively. In summary, we believe that estimates of SNP effects are promising quantitative tools to bring discussions on chromosome regions contributing most effectively to the phenotype expression when using ANN for genomic predictions. 650 $aMarker-assisted selection 650 $aNeural networks 650 $aParâmetro Genético 653 $aGenetic parameters 653 $aQTL 653 $aRedes neurais 700 1 $aCRUZ, C. D. 700 1 $aVIEIRA, R. A. M. 700 1 $aRESENDE, M. D. V. de 700 1 $aLOPES, P. S. 700 1 $aSIQUEIRA, O. H. G. B. D. de 700 1 $aSILVA, F. F. e 773 $tLivestock Science$gv. 191, p. 91-96, Sept. 2016.
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