| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Meio Ambiente. Para informações adicionais entre em contato com cnpma.biblioteca@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Meio Ambiente. |
|
Data corrente: |
31/10/2014 |
|
Data da última atualização: |
31/10/2014 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
CLEMENTE, Z.; CASTRO, V. L. S. S. de; MOURA, M. A. M.; JONSSON, C. M.; FRACETO, L. F. |
|
Afiliação: |
ZAIRA CLEMENTE, IB-UNICAMP; VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; MONICA ACAUI MARCONDES DE MOURA, IB-APTA; CLAUDIO MARTIN JONSSON, CNPMA; LEONARDO FERNANDES FRACETO, UNESP. |
|
Título: |
Toxicity assessment of TiO2 nanoparticles in zebrafish embryos underdifferent exposure conditions. |
|
Ano de publicação: |
2014 |
|
Fonte/Imprenta: |
Aquatic Toxicology, Amsterdam, v. 147, p. 129-139, 2014. |
|
Idioma: |
Inglês |
|
Conteúdo: |
Abstract: The popularity of TiO2 nanoparticles (nano-TiO2) lies in their wide range of nanotechnological applications, together with low toxicity. Meanwhile, recent studies have shown that the photocatalytic properties of this material can result in alterations in their behavior in the environment, causing effects that have not yet been fully elucidated. The objective of this study was to evaluate the toxicity of two formulations of nano-TiO2 under different illumination conditions, using an experimental model coherent with the principle of the three Rs of alternative animal experimentation (reduction, refinement, and replacement). Embryos of the fish Danio rerio were exposed for 96 h to different concentrations of nano-TiO2 in the form of anatase (TA) or an anatase/rutile mixture (TM), under either visible light or a combination of visible and ultraviolet light (UV). The acute toxicity and sublethal parameters evaluated included survival rates, malformation, hatching, equilibrium, and overall length of the larvae, together with biochemical biomarkers (specific activities of catalase (CAT), glutathione S-transferase (GST), and acid phosphatase (AP)). Both TA and TM caused accelerated hatching of the larvae. Under UV irradiation, there was greater mortality of the larvae of the groups exposed to TM, compared to those exposed to TA. Exposure to TM under UV irradiation altered the equilibrium of the larvae. Alterations in the activities of CAT and GST were indicative of oxidative stress, although no clear dose-response relationship was observed. The effects of nano-TiO2 appeared to depend on both the type of formulation and the illumination condition. The findings contribute to elucidation of the factors involved in the toxicity of these nanoparticles, as well as to the establishment of protocols for risk assessments of nanotechnology. MenosAbstract: The popularity of TiO2 nanoparticles (nano-TiO2) lies in their wide range of nanotechnological applications, together with low toxicity. Meanwhile, recent studies have shown that the photocatalytic properties of this material can result in alterations in their behavior in the environment, causing effects that have not yet been fully elucidated. The objective of this study was to evaluate the toxicity of two formulations of nano-TiO2 under different illumination conditions, using an experimental model coherent with the principle of the three Rs of alternative animal experimentation (reduction, refinement, and replacement). Embryos of the fish Danio rerio were exposed for 96 h to different concentrations of nano-TiO2 in the form of anatase (TA) or an anatase/rutile mixture (TM), under either visible light or a combination of visible and ultraviolet light (UV). The acute toxicity and sublethal parameters evaluated included survival rates, malformation, hatching, equilibrium, and overall length of the larvae, together with biochemical biomarkers (specific activities of catalase (CAT), glutathione S-transferase (GST), and acid phosphatase (AP)). Both TA and TM caused accelerated hatching of the larvae. Under UV irradiation, there was greater mortality of the larvae of the groups exposed to TM, compared to those exposed to TA. Exposure to TM under UV irradiation altered the equilibrium of the larvae. Alterations in the activities of CAT and GST were indicative of oxidati... Mostrar Tudo |
|
Palavras-Chave: |
Biomarker; Dióxido de titânio; FET; Fish Embryo Test; Nanoecotoxicologia; Nanotoxicology. |
|
Thesagro: |
Peixe de água doce; Raio ultravioleta; Toxidez. |
|
Thesaurus Nal: |
Danio rerio; Ecotoxicology; Nanoparticles; Nanotechnology; oxidative stress; Toxicity; Ultraviolet radiation. |
|
Categoria do assunto: |
H Saúde e Patologia |
|
Marc: |
LEADER 02888naa a2200361 a 4500
001 1998932
005 2014-10-31
008 2014 bl uuuu u00u1 u #d
100 1 $aCLEMENTE, Z.
245 $aToxicity assessment of TiO2 nanoparticles in zebrafish embryos underdifferent exposure conditions.$h[electronic resource]
260 $c2014
520 $aAbstract: The popularity of TiO2 nanoparticles (nano-TiO2) lies in their wide range of nanotechnological applications, together with low toxicity. Meanwhile, recent studies have shown that the photocatalytic properties of this material can result in alterations in their behavior in the environment, causing effects that have not yet been fully elucidated. The objective of this study was to evaluate the toxicity of two formulations of nano-TiO2 under different illumination conditions, using an experimental model coherent with the principle of the three Rs of alternative animal experimentation (reduction, refinement, and replacement). Embryos of the fish Danio rerio were exposed for 96 h to different concentrations of nano-TiO2 in the form of anatase (TA) or an anatase/rutile mixture (TM), under either visible light or a combination of visible and ultraviolet light (UV). The acute toxicity and sublethal parameters evaluated included survival rates, malformation, hatching, equilibrium, and overall length of the larvae, together with biochemical biomarkers (specific activities of catalase (CAT), glutathione S-transferase (GST), and acid phosphatase (AP)). Both TA and TM caused accelerated hatching of the larvae. Under UV irradiation, there was greater mortality of the larvae of the groups exposed to TM, compared to those exposed to TA. Exposure to TM under UV irradiation altered the equilibrium of the larvae. Alterations in the activities of CAT and GST were indicative of oxidative stress, although no clear dose-response relationship was observed. The effects of nano-TiO2 appeared to depend on both the type of formulation and the illumination condition. The findings contribute to elucidation of the factors involved in the toxicity of these nanoparticles, as well as to the establishment of protocols for risk assessments of nanotechnology.
650 $aDanio rerio
650 $aEcotoxicology
650 $aNanoparticles
650 $aNanotechnology
650 $aoxidative stress
650 $aToxicity
650 $aUltraviolet radiation
650 $aPeixe de água doce
650 $aRaio ultravioleta
650 $aToxidez
653 $aBiomarker
653 $aDióxido de titânio
653 $aFET
653 $aFish Embryo Test
653 $aNanoecotoxicologia
653 $aNanotoxicology
700 1 $aCASTRO, V. L. S. S. de
700 1 $aMOURA, M. A. M.
700 1 $aJONSSON, C. M.
700 1 $aFRACETO, L. F.
773 $tAquatic Toxicology, Amsterdam$gv. 147, p. 129-139, 2014.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Meio Ambiente (CNPMA) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 63 | |
| 6. |  | PEREIRA, R. B.; LUCAS, G. C.; PERINA, F. J.; RIBEIRO JUNIOR, P. M.; ALVES, E. Citronella essential oil in the control and activation of coffee plants defense response against rust and brown eye spot. Ciência e agrotecnologia, Lavras, v. 36, n. 4, p. 383-390, jul./ago. 2012.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Hortaliças. |
|    |
| 10. | | PEREIRA, R. B.; LUCAS, G. C.; CARVALHO, A. D. F.; RIBEIRO JÚNIOR, P. M. Severidade da queima das folhas e quantificação de fenóis solúveis totais e lignina solúvel em cultivares de cenoura. Tropical Plant Pathology, Brasília, DF, v. 36, p. 974, 2011. 1 CD-ROM. Suplemento. Edição dos resumos do 44º Congresso Brasileiro de Fitopatologia, 2011, Bento Gonçalves. Resumo 1265.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Hortaliças. |
| |
| 13. | | PEREIRA, R. B.; CARVALHO, A. D. F.; PINHEIRO, J. B.; RIBEIRO JUNIOR, P. M. Ocorrência do complexo da queima das folhas em diferentes fases de desenvolvimento da cenoura. Tropical Plant Pathology, Brasília, DF, v. 36, p. 914, 2011. 1 CD-ROM. Suplemento. Edição dos resumos do 44º Congresso Brasileiro de Fitopatologia, 2011, Bento Gonçalves. Resumo 1266.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Hortaliças. |
| |
| 16. | | PEREIRA, R. B.; RESENDE, M. L. V.; RIBEIRO JÚNIOR, P. M.; AMARAL, D. R.; LUCAS, G. C.; CAVALCANTI, F. R. Ativação de defesa em cacaueiro contra a murcha-de-verticílio por extratos naturais e acibenzolar-S-metil. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 43, n. 2, p. 171-178, fev. 2008 Título em inglês: Activation of defence responses on cocoa against Verticillium wilt by natural extracts and acibenzolar-S-methyl.| Biblioteca(s): Embrapa Unidades Centrais. |
| |
| 17. | | LUZ, T. A.; ARAÚJO, A. L. de S; SILVA, J. L. da; RIBEIRO JUNIOR, P. M.; ANGELOTTI, F. Como o aumento da temperatura do ar interfere na infecção do oidio em meloeiro. In: CONGRESSO INTERNACIONAL SOBRE MUDANÇAS CLIMÁTICAS E SUAS CONSEQUÊNCIAS EM TERRITÓRIOS SEMIÁRIDOS, 1., 2024, Juazeiro, BA. Anais... Juazeiro, BA: UNIVASF: Universidade do Estado da Bahia, 2025. p. 27-28.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Semiárido. |
| |
| 18. | | SANTOS, R. F. da S.; BARROS, F. P.; BATISTA, D. da C.; RIBEIRO JUNIOR, P. M.; BARBOSA, M. A. G. Efeito do tratamento com água quente na sobrevivência de Lasiodiplodia theobromae, agente causal da morte descendente da videira. In: JORNADA DE INICIAÇÃO CIENTÍFICA DA EMBRAPA SEMIÁRIDO, 14., 2019, Petrolina. Anais... Petrolina: Embrapa Semiárido, 2019. p. 215-218. (Embrapa Semiárido. Documentos, 288).| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Semiárido. |
| |
| 19. | | PEREIRA, R. B.; ALVES, E.; RIBEIRO JÚNIOR, P. M.; RESENDE, M. L. V. de; LUCAS, G. C.; FERREIRA, J. B. Extrato de casca de café, óleo essencial de tomilho e acibenzolar-S-metil no manejo da cercosporiose-do-cafeeiro. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 43, n. 10, p. 1287-1296, out. 2008. Título em inglês: Coffee berry husk extract, thyme essential oil and acibenzolar-S-methyl in the control of brown eye spot of coffee tree.| Biblioteca(s): Embrapa Unidades Centrais. |
| |
| 20. | | LOURENÇO, D. da S.; BARROS, F. P.; SANTOS, R. F. da S.; RIBEIRO JUNIOR, P. M.; BARBOSA, M. A. G. Reação de cultivares de videira ao oídio no Submédio do Vale do São Francisco. In: JORNADA DE INICIAÇÃO CIENTÍFICA DA EMBRAPA SEMIÁRIDO, 14., 2019, Petrolina. Anais... Petrolina: Embrapa Semiárido, 2019. p. 237-241. (Embrapa Semiárido. Documentos, 288).| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Semiárido. |
| |
| Registros recuperados : 63 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
