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Registro Completo |
Biblioteca(s): |
Embrapa Semiárido; Embrapa Uva e Vinho. |
Data corrente: |
21/05/2014 |
Data da última atualização: |
02/04/2019 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
DENNY, C.; LAZARINI, J. G.; FRANCHIN, M.; MELO, P. S.; PEREIRA, G. E.; MASSARIOLI, A. P.; MORENO, I. A. M.; PASCHOAL, J. A. R.; ALENCAR, S. M.; ROSALEN, P. L. |
Afiliação: |
Piracicaba Dental School, Department of Physiological Sciences, University of Campinas; Piracicaba Dental School, Department of Physiological Sciences, University of Campinas; Piracicaba Dental School, Department of Physiological Sciences, University of Campinas; Department of Agri-food Industry, Food and Nutrition, ‘Luiz de Queiroz’ College of Agriculture, University of São Paulo; GIULIANO ELIAS PEREIRA, CNPUV; Department of Agri-food Industry, Food and Nutrition, ‘Luiz de Queiroz’ College of Agriculture, University of São Paulo; Department of Agri-food Industry, Food and Nutrition, ‘Luiz de Queiroz’ College of Agriculture, University of São Paulo; Department of Physics and Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo; Department of Agri-food Industry, Food and Nutrition, ‘Luiz de Queiroz’ College of Agriculture, University of São Paulo; Piracicaba Dental School, Department of Physiological Sciences, University of Campinas. |
Título: |
Bioprospection of Petit Verdot grape pomace as a source of anti-inflammatory compounds. |
Ano de publicação: |
2014 |
Fonte/Imprenta: |
Journal of Functional Foods, v. 8, p. 292-300, 2014. |
Idioma: |
Inglês |
Conteúdo: |
The aim of this study was to evaluate the anti-inflammatory activity of Petit Verdot Extract and hexane, chloroform and ethyl acetate fractions obtained from grape pomace, in addition to identifying active compounds. The PVE and EAF reduced significantly paw edema and neutrophil migration when compared with control groups. The PVE reduced levels of TNF-α and IL1-β in the peritoneal fluid, whereas the EAF did not reduce cytokines significantly. Two hydroxybenzoic acids, two proanthocyanidins, three flavan-3-ol monomers and three anthocyanins were identified in the PVE and EAF by LC-MS/MS. The stilbene transresveratrol was identified only in the EAF. The phenolic compounds were quantified using HPLC-DAD analysis, except for the stilbenes, which were not sensible for the detection by the method. Since PVE and EAF showed significantly anti-inflammatory effects and high concentration of phenolic compounds, we concluded that Petit Verdot pomace could be an interesting source of anti-inflammatory bioactives. |
Palavras-Chave: |
Bagaço de uva; Citocinas; Petit Verdot; Subprodutos. |
Thesagro: |
Antiinflamatorio; Bagaço; Composto fenolico; Uva; Vitis Vinifera. |
Thesaurus Nal: |
Anti-inflammatory activity; Grape pomace; Grapes; Phenolic compounds. |
Categoria do assunto: |
-- F Plantas e Produtos de Origem Vegetal |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/102411/1/Bioprospection.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/105261/1/Giuliano-2014.pdf
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Marc: |
LEADER 02055naa a2200385 a 4500 001 1986684 005 2019-04-02 008 2014 bl uuuu u00u1 u #d 100 1 $aDENNY, C. 245 $aBioprospection of Petit Verdot grape pomace as a source of anti-inflammatory compounds. 260 $c2014 520 $aThe aim of this study was to evaluate the anti-inflammatory activity of Petit Verdot Extract and hexane, chloroform and ethyl acetate fractions obtained from grape pomace, in addition to identifying active compounds. The PVE and EAF reduced significantly paw edema and neutrophil migration when compared with control groups. The PVE reduced levels of TNF-α and IL1-β in the peritoneal fluid, whereas the EAF did not reduce cytokines significantly. Two hydroxybenzoic acids, two proanthocyanidins, three flavan-3-ol monomers and three anthocyanins were identified in the PVE and EAF by LC-MS/MS. The stilbene transresveratrol was identified only in the EAF. The phenolic compounds were quantified using HPLC-DAD analysis, except for the stilbenes, which were not sensible for the detection by the method. Since PVE and EAF showed significantly anti-inflammatory effects and high concentration of phenolic compounds, we concluded that Petit Verdot pomace could be an interesting source of anti-inflammatory bioactives. 650 $aAnti-inflammatory activity 650 $aGrape pomace 650 $aGrapes 650 $aPhenolic compounds 650 $aAntiinflamatorio 650 $aBagaço 650 $aComposto fenolico 650 $aUva 650 $aVitis Vinifera 653 $aBagaço de uva 653 $aCitocinas 653 $aPetit Verdot 653 $aSubprodutos 700 1 $aLAZARINI, J. G. 700 1 $aFRANCHIN, M. 700 1 $aMELO, P. S. 700 1 $aPEREIRA, G. E. 700 1 $aMASSARIOLI, A. P. 700 1 $aMORENO, I. A. M. 700 1 $aPASCHOAL, J. A. R. 700 1 $aALENCAR, S. M. 700 1 $aROSALEN, P. L. 773 $tJournal of Functional Foods$gv. 8, p. 292-300, 2014.
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Registro original: |
Embrapa Uva e Vinho (CNPUV) |
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Registros recuperados : 2 | |
1. |  | DENNY, C.; LAZARINI, J. G.; FRANCHIN, M.; MELO, P. S.; PEREIRA, G. E.; MASSARIOLI, A. P.; MORENO, I. A. M.; PASCHOAL, J. A. R.; ALENCAR, S. M.; ROSALEN, P. L. Bioprospection of Petit Verdot grape pomace as a source of anti-inflammatory compounds. Journal of Functional Foods, v. 8, p. 292-300, 2014.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
Biblioteca(s): Embrapa Semiárido; Embrapa Uva e Vinho. |
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2. |  | MELO, P. S.; MASSARIOLI, A. P.; DENNY, C.; SANTOS, L. F. dos; FRANCHIN, M.; PEREIRA, G. E.; VIEIRA, T. M. F. de S.; ROSALEN, P. L.; ALENCAR, S. M. de. Winery by-products: extraction optimization, phenolic composition and cytotoxic evaluation to act as a new source of scavenging of reactive oxygen species. Food Chemistry, v. 181, p. 160-169, Aug. 2015.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Semiárido; Embrapa Uva e Vinho. |
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Registros recuperados : 2 | |
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