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Registro Completo |
Biblioteca(s): |
Embrapa Pantanal. |
Data corrente: |
07/04/1999 |
Data da última atualização: |
29/03/2017 |
Autoria: |
FRANKE, C. R.; GREINER, M.; MEHLITZ, D. |
Título: |
Investigations on naturally occurring Trypanosoma evansi infections in horses, cattle, dogs and capybaras (Hydrochaeris hydroichaeris) in Pantanal de Pocone (Mato Grosso, Brazil). |
Ano de publicação: |
1994 |
Fonte/Imprenta: |
Acta Tropica, v.58, n.2, p.159-169, 1994. |
Idioma: |
Inglês |
Conteúdo: |
The prevalence of Mal de Cadeiras - Portuguese for Trypanosoma (T.) evansi infections in horses - as well as the prevalence of T. evansi infections in cattle, dogs and free-ranging capybaras (Hydrochaeris hydrochaeris) was investigated in Pantanal de Pocone (Mato Grosso, Brasil). In 0.3, 8.6 and 8.0% of the horses, dogs and capybaras, respectively, infection was detected using standard parasitological methods. A seroprevalence of 4.1, 2.3, 7.1 and 22.0% was found in horses, cattle, dogs and capybaras, respectively, using an enzyme-linked immunosorbent assay for the detection of T. evansi antigen (Ag-ELISA), whereas 9.6, 4.2, 18.6 and 14.0% of the animals investigated were reactive in a T. evansi antibody (Ab-) ELISA. Positive ELISA results (high responder) were identified using computer-assisted mixture analysis (C.A.MAN). Agglutinating antibodies were detected by the T. evansi card agglutination test for trypanosomiasis (CATT/T. evansi) in 14.6%, 1.3%, 15.7% and 22.0% of the horses, cattle, dogs and capybaras, respectively. A moderate but significant (kappa test; p<0.05) agreement beyond chance levels was observed between Ab-ELISA and CATT results but generally not between antibody and antigen detection tests. Therefore, in an attempt to maximize the information yield of the three serodiagnostic tests, their results were numerically scored (negative=0, intermediate=1, positive=2) and added up to a total score (TS) which was considered indicative for infection when TS>4 (results of the Ag-ELISA received double weight). Estimates of seroprevalence according to TS were 13.2, 4.7, 30.0 and 24.0% for horses, cattle, dogs and capybaras, respectively. Identical isoenzyme profiles, known as zymodeme 58 (T. evansi MCAN/BR/86/H), were found in all T. evansi stocks isolated in the study area (six from dogs, one from a horse and one from a capybara). From the results of this study it can be inferred that Mal de Cadeiras is endemic in Pantanal de Pocone. Although clinical and parasitological findings support the possible role of the capybara as a reservoir host of T. evansi, dogs and cattle - due to their close contaxct with horses should rather be regarded as efficient resrvoir hosts for Mal de Cadeiras in the study area. MenosThe prevalence of Mal de Cadeiras - Portuguese for Trypanosoma (T.) evansi infections in horses - as well as the prevalence of T. evansi infections in cattle, dogs and free-ranging capybaras (Hydrochaeris hydrochaeris) was investigated in Pantanal de Pocone (Mato Grosso, Brasil). In 0.3, 8.6 and 8.0% of the horses, dogs and capybaras, respectively, infection was detected using standard parasitological methods. A seroprevalence of 4.1, 2.3, 7.1 and 22.0% was found in horses, cattle, dogs and capybaras, respectively, using an enzyme-linked immunosorbent assay for the detection of T. evansi antigen (Ag-ELISA), whereas 9.6, 4.2, 18.6 and 14.0% of the animals investigated were reactive in a T. evansi antibody (Ab-) ELISA. Positive ELISA results (high responder) were identified using computer-assisted mixture analysis (C.A.MAN). Agglutinating antibodies were detected by the T. evansi card agglutination test for trypanosomiasis (CATT/T. evansi) in 14.6%, 1.3%, 15.7% and 22.0% of the horses, cattle, dogs and capybaras, respectively. A moderate but significant (kappa test; p<0.05) agreement beyond chance levels was observed between Ab-ELISA and CATT results but generally not between antibody and antigen detection tests. Therefore, in an attempt to maximize the information yield of the three serodiagnostic tests, their results were numerically scored (negative=0, intermediate=1, positive=2) and added up to a total score (TS) which was considered indicative for infection when TS>4 (res... Mostrar Tudo |
Palavras-Chave: |
Anti-corpos; Antibody; Antigen; Brasil; Cachorro; Capybara; Disease; Dog; Horse. |
Thesagro: |
Animal; Antígeno; Capivara; Cavalo; Doença; Elisa; Gado. |
Thesaurus Nal: |
cattle; Pantanal; Trypanosoma evansi. |
Categoria do assunto: |
-- |
Marc: |
LEADER 03217naa a2200373 a 4500 001 1795056 005 2017-03-29 008 1994 bl --- 0-- u #d 100 1 $aFRANKE, C. R. 245 $aInvestigations on naturally occurring Trypanosoma evansi infections in horses, cattle, dogs and capybaras (Hydrochaeris hydroichaeris) in Pantanal de Pocone (Mato Grosso, Brazil). 260 $c1994 520 $aThe prevalence of Mal de Cadeiras - Portuguese for Trypanosoma (T.) evansi infections in horses - as well as the prevalence of T. evansi infections in cattle, dogs and free-ranging capybaras (Hydrochaeris hydrochaeris) was investigated in Pantanal de Pocone (Mato Grosso, Brasil). In 0.3, 8.6 and 8.0% of the horses, dogs and capybaras, respectively, infection was detected using standard parasitological methods. A seroprevalence of 4.1, 2.3, 7.1 and 22.0% was found in horses, cattle, dogs and capybaras, respectively, using an enzyme-linked immunosorbent assay for the detection of T. evansi antigen (Ag-ELISA), whereas 9.6, 4.2, 18.6 and 14.0% of the animals investigated were reactive in a T. evansi antibody (Ab-) ELISA. Positive ELISA results (high responder) were identified using computer-assisted mixture analysis (C.A.MAN). Agglutinating antibodies were detected by the T. evansi card agglutination test for trypanosomiasis (CATT/T. evansi) in 14.6%, 1.3%, 15.7% and 22.0% of the horses, cattle, dogs and capybaras, respectively. A moderate but significant (kappa test; p<0.05) agreement beyond chance levels was observed between Ab-ELISA and CATT results but generally not between antibody and antigen detection tests. Therefore, in an attempt to maximize the information yield of the three serodiagnostic tests, their results were numerically scored (negative=0, intermediate=1, positive=2) and added up to a total score (TS) which was considered indicative for infection when TS>4 (results of the Ag-ELISA received double weight). Estimates of seroprevalence according to TS were 13.2, 4.7, 30.0 and 24.0% for horses, cattle, dogs and capybaras, respectively. Identical isoenzyme profiles, known as zymodeme 58 (T. evansi MCAN/BR/86/H), were found in all T. evansi stocks isolated in the study area (six from dogs, one from a horse and one from a capybara). From the results of this study it can be inferred that Mal de Cadeiras is endemic in Pantanal de Pocone. Although clinical and parasitological findings support the possible role of the capybara as a reservoir host of T. evansi, dogs and cattle - due to their close contaxct with horses should rather be regarded as efficient resrvoir hosts for Mal de Cadeiras in the study area. 650 $acattle 650 $aPantanal 650 $aTrypanosoma evansi 650 $aAnimal 650 $aAntígeno 650 $aCapivara 650 $aCavalo 650 $aDoença 650 $aElisa 650 $aGado 653 $aAnti-corpos 653 $aAntibody 653 $aAntigen 653 $aBrasil 653 $aCachorro 653 $aCapybara 653 $aDisease 653 $aDog 653 $aHorse 700 1 $aGREINER, M. 700 1 $aMEHLITZ, D. 773 $tActa Tropica$gv.58, n.2, p.159-169, 1994.
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Embrapa Pantanal (CPAP) |
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Registro Completo
Biblioteca(s): |
Embrapa Agroindústria Tropical. |
Data corrente: |
19/07/2016 |
Data da última atualização: |
04/04/2017 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 2 |
Autoria: |
SOUZA, L. G. da S.; ALMEIDA, M. C. S.; LEMOS, T. L. G.; RIBEIRO, P. R. V.; BRITO, E. S. de; SILVA, V. L. M.; SILVA, A. M. S.; FILHO, R. B.; COSTA, J. G. M.; RODRIGUES, F. F. G.; BARRETO, F. S.; MORAES, M. O. de. |
Afiliação: |
Luciana G. da S. Souza, Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará.; Macia C. S. Almeida, Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará.; Telma L. G. Lemos, Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará.; Paulo R. V. Ribeiro, Embrapa Agroindustria Tropical.; EDY SOUSA DE BRITO, CNPAT; Vera L. M. Silva, Departamento de Química & QOPNA, University of Aveir, Portugal.; Artur M. S. Silva, Departamento de Química & QOPNA, University of Aveir, Portugal.; Raimundo Braz-Filho, Laboratório de Ciências Químicas, Universidade Estadual do Norte Fluminense Darcy Ribeiro.; José G. M. Costa, Laboratório de Pesquisa de Produtos Naturais, Universidade Regional do Cariri.; Fábio F. G. Rodrigues, Laboratório de Pesquisa de Produtos Naturais, Universidade Regional do Cariri.; Francisco S. Barreto, Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará.; Manoel O. de Moraes, Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará. |
Título: |
Synthesis, antibacterial and cytotoxic activities of new biflorin-based hydrazones and oximes. |
Ano de publicação: |
2016 |
Fonte/Imprenta: |
Bioorganic & Medicinal Chemistry Letters, v. 26, n. 2, p. 435-439, 2016. |
Idioma: |
Inglês |
Palavras-Chave: |
Antibacteriano; Antitumoral; Biflorina; Hidrazonas; Oximas. |
Categoria do assunto: |
-- |
Marc: |
LEADER 00893naa a2200301 a 4500 001 2049133 005 2017-04-04 008 2016 bl uuuu u00u1 u #d 100 1 $aSOUZA, L. G. da S. 245 $aSynthesis, antibacterial and cytotoxic activities of new biflorin-based hydrazones and oximes.$h[electronic resource] 260 $c2016 653 $aAntibacteriano 653 $aAntitumoral 653 $aBiflorina 653 $aHidrazonas 653 $aOximas 700 1 $aALMEIDA, M. C. S. 700 1 $aLEMOS, T. L. G. 700 1 $aRIBEIRO, P. R. V. 700 1 $aBRITO, E. S. de 700 1 $aSILVA, V. L. M. 700 1 $aSILVA, A. M. S. 700 1 $aFILHO, R. B. 700 1 $aCOSTA, J. G. M. 700 1 $aRODRIGUES, F. F. G. 700 1 $aBARRETO, F. S. 700 1 $aMORAES, M. O. de 773 $tBioorganic & Medicinal Chemistry Letters$gv. 26, n. 2, p. 435-439, 2016.
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Embrapa Agroindústria Tropical (CNPAT) |
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