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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
06/11/2002 |
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Data da última atualização: |
06/11/2002 |
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Autoria: |
ADAMS, T. E.; SAKURAI, H.; ADAMS, B. M. |
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Título: |
Effect of stress-like concentrations of cortisol on estradiol-dependent expression of gonadotropin-releasing hormone receptor in orchidectomized sheep. |
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Ano de publicação: |
1999 |
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Fonte/Imprenta: |
Biology of Reproduction, v. 60, n. 1, p. 164-168, 1999. |
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Idioma: |
Inglês |
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Conteúdo: |
The effect of stress-like concentrations of cortisol (C) on estrogen-dependent expression of GnRH receptor was evaluated using orchidectomized sheep (wethers; n = 6 anímais per group). C (5.0 mg/50 kg per hour; groups 1-4) or a comparable volume of vehicle (groups 5-8) was delivered by continuous in- fusion for 48 h. During the final 24 h of infusion, anímais received concurrent infusion of estradiol (E2) at rates of O (groups 1 and 5), 0.5 (groups 2 and 6), 2.0 (groups 3 and 7), or 8.0 (groups 4 and 8) Jl.g/50 kg per hour. Pituitary tissue was collected at the end of infusion. Although C did not affect (p > 0.05) the basal concentration of GnRH receptor or GnRH receptor mRNA, it reduced (p < 0.05) the increase in receptor and receptor mRNA induced by concurrent administration of 0.5 ug E2/50 kg per hour. In contrast, the increase in GnRH receptor expression induced by higher levels of estrogen stimulation was not affected (p > 0.05) by concurrent administration of C. The effect of C on the temporal pattern of E2-depen- dent increase in GnRH receptor expression was assessed using wethers receiving E2 (0.5 Jl.g/50 kg per hour) by continuous in- fusion for O (groups 1 and 5), 24 (groups 2 and 6), 48 (groups 3 and 7), or 72 h (groups 4 and 8). Animals received C (5.0 mg/ 50 kg per hour; groups 1-4) or vehicle (groups 5-8) beginning 24 h before, and continuing throughout, the E2 delivery period. Stress-like concentrations of C reduced (p < 0.05) the increase in GnRH receptor and receptor mRNA induced after 24 h of E2 stimulation. However, the suppressive effect of C was transient, and tissue levels of GnRH receptor and receptor mRNA were comparable after 72 h of E2 infusion in anímais receiving C or vehicle alone. Collectively these observations demonstrate that C suppresses estrogen-dependent increase in tissue concentrations of GnRH receptor and receptor mRNA. However, this effect of C is transient and not evident in animals receiving moderate to high levels of estrogen stimulation. This transient suppression of GnRH receptor expression mar account, at least in part, for the anti-gonadal effect of glucocorticoids. MenosThe effect of stress-like concentrations of cortisol (C) on estrogen-dependent expression of GnRH receptor was evaluated using orchidectomized sheep (wethers; n = 6 anímais per group). C (5.0 mg/50 kg per hour; groups 1-4) or a comparable volume of vehicle (groups 5-8) was delivered by continuous in- fusion for 48 h. During the final 24 h of infusion, anímais received concurrent infusion of estradiol (E2) at rates of O (groups 1 and 5), 0.5 (groups 2 and 6), 2.0 (groups 3 and 7), or 8.0 (groups 4 and 8) Jl.g/50 kg per hour. Pituitary tissue was collected at the end of infusion. Although C did not affect (p > 0.05) the basal concentration of GnRH receptor or GnRH receptor mRNA, it reduced (p < 0.05) the increase in receptor and receptor mRNA induced by concurrent administration of 0.5 ug E2/50 kg per hour. In contrast, the increase in GnRH receptor expression induced by higher levels of estrogen stimulation was not affected (p > 0.05) by concurrent administration of C. The effect of C on the temporal pattern of E2-depen- dent increase in GnRH receptor expression was assessed using wethers receiving E2 (0.5 Jl.g/50 kg per hour) by continuous in- fusion for O (groups 1 and 5), 24 (groups 2 and 6), 48 (groups 3 and 7), or 72 h (groups 4 and 8). Animals received C (5.0 mg/ 50 kg per hour; groups 1-4) or vehicle (groups 5-8) beginning 24 h before, and continuing throughout, the E2 delivery period. Stress-like concentrations of C reduced (p < 0.05) the increase in GnRH receptor and... Mostrar Tudo |
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Palavras-Chave: |
Gonadotropina; Receptor. |
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Thesagro: |
Estradiol; Hormônio; Ovino; Stress. |
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Thesaurus Nal: |
cortisol. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02823naa a2200229 a 4500
001 1528814
005 2002-11-06
008 1999 bl uuuu u00u1 u #d
100 1 $aADAMS, T. E.
245 $aEffect of stress-like concentrations of cortisol on estradiol-dependent expression of gonadotropin-releasing hormone receptor in orchidectomized sheep.
260 $c1999
520 $aThe effect of stress-like concentrations of cortisol (C) on estrogen-dependent expression of GnRH receptor was evaluated using orchidectomized sheep (wethers; n = 6 anímais per group). C (5.0 mg/50 kg per hour; groups 1-4) or a comparable volume of vehicle (groups 5-8) was delivered by continuous in- fusion for 48 h. During the final 24 h of infusion, anímais received concurrent infusion of estradiol (E2) at rates of O (groups 1 and 5), 0.5 (groups 2 and 6), 2.0 (groups 3 and 7), or 8.0 (groups 4 and 8) Jl.g/50 kg per hour. Pituitary tissue was collected at the end of infusion. Although C did not affect (p > 0.05) the basal concentration of GnRH receptor or GnRH receptor mRNA, it reduced (p < 0.05) the increase in receptor and receptor mRNA induced by concurrent administration of 0.5 ug E2/50 kg per hour. In contrast, the increase in GnRH receptor expression induced by higher levels of estrogen stimulation was not affected (p > 0.05) by concurrent administration of C. The effect of C on the temporal pattern of E2-depen- dent increase in GnRH receptor expression was assessed using wethers receiving E2 (0.5 Jl.g/50 kg per hour) by continuous in- fusion for O (groups 1 and 5), 24 (groups 2 and 6), 48 (groups 3 and 7), or 72 h (groups 4 and 8). Animals received C (5.0 mg/ 50 kg per hour; groups 1-4) or vehicle (groups 5-8) beginning 24 h before, and continuing throughout, the E2 delivery period. Stress-like concentrations of C reduced (p < 0.05) the increase in GnRH receptor and receptor mRNA induced after 24 h of E2 stimulation. However, the suppressive effect of C was transient, and tissue levels of GnRH receptor and receptor mRNA were comparable after 72 h of E2 infusion in anímais receiving C or vehicle alone. Collectively these observations demonstrate that C suppresses estrogen-dependent increase in tissue concentrations of GnRH receptor and receptor mRNA. However, this effect of C is transient and not evident in animals receiving moderate to high levels of estrogen stimulation. This transient suppression of GnRH receptor expression mar account, at least in part, for the anti-gonadal effect of glucocorticoids.
650 $acortisol
650 $aEstradiol
650 $aHormônio
650 $aOvino
650 $aStress
653 $aGonadotropina
653 $aReceptor
700 1 $aSAKURAI, H.
700 1 $aADAMS, B. M.
773 $tBiology of Reproduction$gv. 60, n. 1, p. 164-168, 1999.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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| Registros recuperados : 19 | |
| 3. |  | BRAGA, G. J.; PEDREIRA, C. G. S.; HERLING, V. R.; LUZ, P. H. de C. Eficiência de pastejo de capim-marandu submetido a diferentes ofertas de forragem Pesquisa Agropecuária Brasileira, Brasília, DF, v. 42, n. 11, p. 1641-1649, nov. 2007 Título em inglês: Grazing efficiency on marandu palisadegrass as affected by herbage allowance.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 8. | | LUZ, P. H. de C.; QUINTINO, T. A.; SILVA, F. C. da; COLETI, J. T.; BET, J. A. Nutrição mineral e fertilização em cana-de-açúcar. In: SILVA, F. C. da; ALVES, B. J. R.; FREITAS, P. L. de (Ed.). Sistema de produção mecanizada da cana-de-açúcar integrada à produção de energia e alimentos. Brasília, DF: Embrapa, 2017. v. 2, pt. 7, cap. 1, p. 657-730.| Tipo: Capítulo em Livro Técnico-Científico |
| Biblioteca(s): Embrapa Agricultura Digital. |
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| 10. | | SILVA, F. C. da; LUZ, P. H. de C.; ABREU JÚNIOR, C. H.; CESAR, M. A. A.; FREITAS, P. L. de. Aproveitamento, tratamento e disposição de resíduos na cultura de cana-de-açúcar. In: SILVA, F. C. da; ALVES, B. J. R.; FREITAS, P. L. de (Ed.). Sistema de produção mecanizada da cana-de-açúcar integrada à produção de energia e alimentos. Brasília, DF: Embrapa, 2017. v. 2, pt. 8, cap. 1, p. 839-899.| Tipo: Capítulo em Livro Técnico-Científico |
| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Solos. |
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| 11. | | OLIVEIRA, P. P. A.; OLIVEIRA, W. S. de; LUZ, P. H. de C.; HERLING, V. R.; MORIMOTO, T. K.; ROCHA, C. O. Adubação foliar nitrogenada substitutiva em pastagens irrigadas de Panicum maximum cv. Tanzania. In: SYMPOSIUM ON 'GRASSLAND ECOPHYSIOLOGY AND GRAZING ECOLOGY', 2., Curitiba, PR, 2004. 5 p.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 13. | | MARCHESIN, W.; OLIVEIRA, P. P. A.; ALVES, A. C.; LUZ, P. H. de C.; HERLING, V. R.; ROCHA, C. O.; OLIVEIRA, W. S. de. Guia de identificação da sintomatologia nutricional em Brachiaria brizantha cv. Marandu. In: SIMPÓSIO DE INICIAÇÃO CIENTÍFICA DA EMBRAPA PECUÁRIA SUDESTE2006, São Carlos, SP. Anais... São Carlos: Embrapa Pecuária Sudeste, 2006.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 14. | | SILVA, E. T. M. da; MACHADO, A. A.; FORATTO, D.; HERLING, V. R.; LUZ, P. H. de C.; FERRAZ, M.; OLIVEIRA, P. P. A. Eficiência da fixação biológica. In: SIMPÓSIO INTERNACIONAL DE INICIAÇÃO CIENTÍFICA DA UNIVERSIDADE DE SÃO PAULO, 14., 2006, São Paulo. Anais... São Paulo: USP: CNPq: FAPESP, 2006. p. 1.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 15. | | ALVES, A. C.; OLIVEIRA, P. P. A.; HERLING, V. R.; TREVELIN, P. C.; LUZ, P. H. DE C.; ALVES, T. C.; ROCHETTI, R. C.; BARIONI JUNIOR, W. New methods to quantify NH3 volatilization from fertilized surface soil with urea. Revista Brasileira de Ciência do Solo, v. 35, p. 133-140, 2011.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 16. | | HERLING, V. R.; LUZ, P. H. de C.; OLIVEIRA, P. P. A.; MARCHESIN, W. A.; MACEDO, F. B.; ALVES, A. C. Manejo do pasto com vistas a maximizar a produção de ruminantes. In: REIS, R. A.; SIQUEIRA, G. R.; BERTIPAGLIA, L. M. A.; OLIVEIRA, A. P.; MELO, G. M. P.; BERNARDES, T. F. Volumosos na produção de ruminantes. Jaboticabal: FUNEP, 2005. p. 125-157.| Tipo: Capítulo em Livro Técnico-Científico |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 17. | | ALVES, A. C.; OLIVEIRA, P. P. A.; HERLING, V. R.; TRIVELIN, P. C. O.; ALVES, T. C.; ROCHETTI, R. C.; LUZ, P. H. de C.; BARIONI JÚNIOR, W. Métodos para quantificar a volatilização de amômia em solo fertilizado com uréia. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 43., 2006, João Pessoa. Produção animal em biomas tropicais: anais. João Pessoa: SBZ: UFPB, 2006. 4 f. 1 CD-ROM.| Tipo: Artigo em Anais de Congresso / Nota Técnica |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 18. | | LUZ, P. H. de C.; FRANCISCO, A. D. M.; MACEDO, F. B.; FARIA, L. de A.; HERLING, V. R.; ALVES, A. C.; OLIVEIRA, P. P. A. Produtividade e composição bromatológica de milho em sistema de plantio direto submetido a fontes de nitrogênio. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 45., 2008, Lavras, MG. Anais... Lavras: SBZ: UFLA, 2008. 3 p.| Tipo: Artigo em Anais de Congresso / Nota Técnica |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 19. | | ALTARUGIO, L. M.; LOMAN, M. H.; NIRSCHL, M. G.; SILVANO, R. G.; ZAVASCHI, E.; CARNEIRO, L. de M. e S.; VITTI, G. C.; LUZ, P. H. de C.; OTTO, R. Yield performance of soybean and corn subjected to magnesium foliar spray. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 52, n. 12, p. 1185-1191, dez. 2017. Título em portguês: Desempenho produtivo de soja e milho submetidos à aplicação foliar de magnésio.| Biblioteca(s): Embrapa Unidades Centrais. |
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| Registros recuperados : 19 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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