Registro Completo |
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
01/08/1992 |
Data da última atualização: |
12/06/2023 |
Autoria: |
KELLY, J. D.; HALL, C. A. |
Título: |
Resistance of animal helminths to anthelmintics. |
Ano de publicação: |
1979 |
Fonte/Imprenta: |
Advances in Pharmacology and Chemotherapy, v. 16, p. 89-128, 1979. |
Idioma: |
Inglês |
Conteúdo: |
This chapter discusses the resistance of animal helminths to anthelmintics. Resistance is defined as a significant increase in the ability of individuals within a strain to tolerate doses of a compound, which would prove lethal to the majority of individuals in a normal population of the same species. The introduction of phenothiazine and the benzimidazole broad-spectrum anthelmintics, has unfortunately led to the selection of drug-resistant strains of important parasitic helminths. The emergence of an increasing number of resistant helminths is associated with the widespread use and misuse of anthelmintics, and poses important problems for the helminth chemotherapist. Several species of ovine nematodes have developed resistance to anthelmintics after repeated exposures. Field strains of Haemonchus contortus resistant to phenothiazine (coarse particle) were first reported in the United States by Drudge et al. Benzimidazole-resistant strains of H. contortus have now been reported from the United States, Chile, Australia, South Africa, and West Malaysia. Other species of helminths known to have developed resistance to this group of drugs are Trichostrongylus colubriformis and Ostertagia circumcincta. |
Palavras-Chave: |
Controle; Nematodeo; Resistance to anthelmintics. |
Thesagro: |
Anti-Helmíntico; Helminto; Parasitologia; Resistência; Ruminante. |
Thesaurus Nal: |
Animal parasitic nematodes; Helminths; Parasitology; Ruminants. |
Categoria do assunto: |
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |