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Registro Completo
Biblioteca(s):  Embrapa Caprinos e Ovinos.
Data corrente:  01/08/1992
Data da última atualização:  05/12/2023
Autoria:  LEAMASTER, B. R.; SHEN, D. T.; GORHAM, J. R.; LEATHERS, C. W.; WELLS, H. D.
Título:  Efficacy of Corynebacterium pseudotuberculosis bacterin for the immunologic protection of sheep against development of caseous lymphadenitis.
Ano de publicação:  1987
Fonte/Imprenta:  American Journal Veterinary Research, v. 48, n. 5, p. 868-872, 1987.
Idioma:  Inglês
Conteúdo:  Abstract: The efficacy of a Corynebacterium pseudotuberculosis bacterin to protect sheep immunologically against development of caseous lymphadenitis was evaluated in controlled challenge-exposure experiments. Sixty-three mixed-breed, white-faced lambs were used. The lambs were 10 to 12 weeks old and were randomly assigned to 3 groups (21 lambs/group). Group 1 was vaccinated once, using 2 ml of a C pseudotuberculosis bacterin (given subcutaneously) in the right axillary region at the beginning of the study. Group 2 was vaccinated twice; the 1st vaccination was given at the same time that lambs in group 1 were vaccinated and the 2nd vaccination was given 4 weeks later. Group 3 (nonvaccinated controls) was given physiologic saline solution (2 ml, subcutaneously). Each lamb was challenge exposed (ie, given 2 ml of live Corynebacterium pseudotuberculosis inoculum [6 X 10(6) colony-forming units/ml], subcutaneously at 4 different sites) during the 20th week of the study. All lambs were killed and necropsied during week 33. The mean number of abscesses per lamb was 7 for group 1, 4 for group 2, and 32 for group 3. Significant differences in the size of the abscesses were not found between the groups. Results of the study indicated that the vaccine provided immunologic protection of lambs against challenge exposure to Corynebacterium pseudotuberculosis.
Thesagro:  Doença; Linfadenite Caseosa; Ovino.
Thesaurus Nal:  Caseous lymphadenitis; Corynebacterium; Disease control; Disease prevention; Lymphadenitis; Sheep diseases.
Categoria do assunto:  H Saúde e Patologia
Marc:  Mostrar Marc Completo
Registro original:  Embrapa Caprinos e Ovinos (CNPC)
Biblioteca ID Origem Tipo/Formato Classificação Cutter Registro Volume Status URL
CNPC7514 - 1ADDAP - PPSP 01180SP 01180
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