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 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
Registro Completo |
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
01/08/1992 |
Data da última atualização: |
04/12/2023 |
Autoria: |
PEPIN, M.; PARDON, P.; MARLY, J.; LANTIER, F. |
Título: |
Corynebacterium pseudotuberculosis infection in adult ewes by inoculation in the external ear. |
Ano de publicação: |
1988 |
Fonte/Imprenta: |
American Journal of Veterinary Research, v. 49, n. 4, p. 459-463, Apr. 1988. |
Idioma: |
Inglês |
Conteúdo: |
Abstract: Caseous lymphadenitis, caused by Corynebacterium pseudotuberculosis, was studied in ewes to devise a reliable method of induced infection that would help to understand mechanisms by which abscesses develop in lymph nodes or internal organs, especially the lungs. Fifteen adult ewes, from a flock where the occurrence of caseous lymphadenitis was unknown, were inoculated SC in the auricle with various doses of a virulent strain of C pseudotuberculosis. Ewes inoculated with at least 10(8) viable corynebacteria develop a strong local reaction that was apparent 4 hours after challenge exposure and lasted 7 to 14 days. Of these ewes, all developed at least 1 abscess and 3 developed multiple abscesses in lymph nodes draining the inoculated auricle and in the lungs. All infected ewes developed a strong antibody response against C pseudotuberculosis exotoxin, which persisted for 3 months. Of 9 ewes infected with 1.2 X 10(8) corynebacteria, 3 developed lesions because of field strains of C pseudotuberculosis and had an increased capacity to limit the dissemination of challenge-inoculum bacteria by developing only one abscess in the draining lymph node (parotid or prescapular lymph node). Seemingly, inoculation in the external ear was a suitable method for obtaining a reproducible infection and indicated that a primary infection might protect against reinfection by limiting dissemination of C pseudotuberculosis. |
Palavras-Chave: |
Linfadenie caseosa. |
Thesagro: |
Doença; Ovino. |
Thesaurus Nal: |
Abscess; Bacterial antibodies; Caseous lymphadenitis; Ear diseases; Ewes; Females; Sheep diseases. |
Categoria do assunto: |
H Saúde e Patologia |
Marc: |
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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