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Biblioteca(s):  Embrapa Caprinos e Ovinos.
Data corrente:  01/08/1992
Data da última atualização:  21/06/2023
Autoria:  DIEKMAN, M. A.; O'CALLAGHAN, P.; NETT, T. M.; NISWENDER, G. D.
Título:  Effect of prostaglandin F2 (alfa) on the number of LH receptors in ovine corpora lutea.
Ano de publicação:  1978
Fonte/Imprenta:  Biology of Reproduction, v. 19, n. 5, p. 1010-1013, 1978.
Idioma:  Inglês
Conteúdo:  Abstract: An experiment was conducted to determine if injections of prostaglandin (PG) F2? influenced the number of receptors for LH in ovine luteal tissue and to compare the time course of change in the numbers of LH receptors and progesterone secretion. Ewes on Day 9 of the estrous cycle were given 2 injections of PGF2?-tham salt (6.7 mg, i.m.) at 4 h intervals. Corpora lutea were removed from each of 6 ewes at 2.5, 7.5, and 22.5 h after the initial injection of PGF2? and from 6 control ewes on Day 10 of the cycle. Jugular blood samples for analysis of progesterone were collected at 20 min intervals for 1 h prior to treatment and at 0.5, 1 or 2 h intervals in ewes in which corpora lutea were collected at 2.5, 7.5 and 22.5 h after injection of PGF2?, respectively. Luteal weight, luteal progesterone concentrations and total number of luteal LH receptors and the number of receptors occupied by endogenous LH were determined. Serum concentrations of progesterone were not decreased at 2.5 h after the initial injection of PGF2?, but had decreased by 7.5 and 22.5 h (P<0.01). There was no change in luteal weight, luteal concentration of progesterone, total number of LH receptors or the number of receptors occupied by LH at 2.5 or 7.5 h when compared to luteal tissue from control ewes. However, each of these parameters had decreased by 22.5 h. The affinity of the receptor for LH did not differ at any of the times studied. These data indicate that progesterone secretion by the corpus... Mostrar Tudo
Palavras-Chave:  Drug effects; Receptors Cell Surface.
Thesagro:  Endocrinologia; Fisiologia; Ovino; Reprodução.
Thesaurus Nal:  Corpus luteum; Endocrinology; Estrus; Luteinizing hormone; Pharmacology; Pregnancy; Progesterone; Prostaglandin-F synthase; Reproduction; Sheep.
Categoria do assunto:  --
Marc:  Mostrar Marc Completo
Registro original:  Embrapa Caprinos e Ovinos (CNPC)
Biblioteca ID Origem Tipo/Formato Classificação Cutter Registro Volume Status URL
CNPC5807 - 1ADDAP - DD
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