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 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
21/06/2023 |
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Autoria: |
DIEKMAN, M. A.; O'CALLAGHAN, P.; NETT, T. M.; NISWENDER, G. D. |
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Título: |
Effect of prostaglandin F2 (alfa) on the number of LH receptors in ovine corpora lutea. |
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Ano de publicação: |
1978 |
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Fonte/Imprenta: |
Biology of Reproduction, v. 19, n. 5, p. 1010-1013, 1978. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: An experiment was conducted to determine if injections of prostaglandin (PG) F2? influenced the number of receptors for LH in ovine luteal tissue and to compare the time course of change in the numbers of LH receptors and progesterone secretion. Ewes on Day 9 of the estrous cycle were given 2 injections of PGF2?-tham salt (6.7 mg, i.m.) at 4 h intervals. Corpora lutea were removed from each of 6 ewes at 2.5, 7.5, and 22.5 h after the initial injection of PGF2? and from 6 control ewes on Day 10 of the cycle. Jugular blood samples for analysis of progesterone were collected at 20 min intervals for 1 h prior to treatment and at 0.5, 1 or 2 h intervals in ewes in which corpora lutea were collected at 2.5, 7.5 and 22.5 h after injection of PGF2?, respectively. Luteal weight, luteal progesterone concentrations and total number of luteal LH receptors and the number of receptors occupied by endogenous LH were determined. Serum concentrations of progesterone were not decreased at 2.5 h after the initial injection of PGF2?, but had decreased by 7.5 and 22.5 h (P<0.01). There was no change in luteal weight, luteal concentration of progesterone, total number of LH receptors or the number of receptors occupied by LH at 2.5 or 7.5 h when compared to luteal tissue from control ewes. However, each of these parameters had decreased by 22.5 h. The affinity of the receptor for LH did not differ at any of the times studied. These data indicate that progesterone secretion by the corpus luteum after PGF2? administration decreased well before (7.5 h) decreases in the number of occupied or unoccupied receptors for LH could be detected (22.5 h). MenosAbstract: An experiment was conducted to determine if injections of prostaglandin (PG) F2? influenced the number of receptors for LH in ovine luteal tissue and to compare the time course of change in the numbers of LH receptors and progesterone secretion. Ewes on Day 9 of the estrous cycle were given 2 injections of PGF2?-tham salt (6.7 mg, i.m.) at 4 h intervals. Corpora lutea were removed from each of 6 ewes at 2.5, 7.5, and 22.5 h after the initial injection of PGF2? and from 6 control ewes on Day 10 of the cycle. Jugular blood samples for analysis of progesterone were collected at 20 min intervals for 1 h prior to treatment and at 0.5, 1 or 2 h intervals in ewes in which corpora lutea were collected at 2.5, 7.5 and 22.5 h after injection of PGF2?, respectively. Luteal weight, luteal progesterone concentrations and total number of luteal LH receptors and the number of receptors occupied by endogenous LH were determined. Serum concentrations of progesterone were not decreased at 2.5 h after the initial injection of PGF2?, but had decreased by 7.5 and 22.5 h (P<0.01). There was no change in luteal weight, luteal concentration of progesterone, total number of LH receptors or the number of receptors occupied by LH at 2.5 or 7.5 h when compared to luteal tissue from control ewes. However, each of these parameters had decreased by 22.5 h. The affinity of the receptor for LH did not differ at any of the times studied. These data indicate that progesterone secretion by the corpus... Mostrar Tudo |
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Palavras-Chave: |
Drug effects; Receptors Cell Surface. |
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Thesagro: |
Endocrinologia; Fisiologia; Ovino; Reprodução. |
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Thesaurus Nal: |
Corpus luteum; Endocrinology; Estrus; Luteinizing hormone; Pharmacology; Pregnancy; Progesterone; Prostaglandin-F synthase; Reproduction; Sheep. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02617naa a2200349 a 4500
001 1519678
005 2023-06-21
008 1978 bl uuuu u00u1 u #d
100 1 $aDIEKMAN, M. A.
245 $aEffect of prostaglandin F2 (alfa) on the number of LH receptors in ovine corpora lutea.$h[electronic resource]
260 $c1978
520 $aAbstract: An experiment was conducted to determine if injections of prostaglandin (PG) F2? influenced the number of receptors for LH in ovine luteal tissue and to compare the time course of change in the numbers of LH receptors and progesterone secretion. Ewes on Day 9 of the estrous cycle were given 2 injections of PGF2?-tham salt (6.7 mg, i.m.) at 4 h intervals. Corpora lutea were removed from each of 6 ewes at 2.5, 7.5, and 22.5 h after the initial injection of PGF2? and from 6 control ewes on Day 10 of the cycle. Jugular blood samples for analysis of progesterone were collected at 20 min intervals for 1 h prior to treatment and at 0.5, 1 or 2 h intervals in ewes in which corpora lutea were collected at 2.5, 7.5 and 22.5 h after injection of PGF2?, respectively. Luteal weight, luteal progesterone concentrations and total number of luteal LH receptors and the number of receptors occupied by endogenous LH were determined. Serum concentrations of progesterone were not decreased at 2.5 h after the initial injection of PGF2?, but had decreased by 7.5 and 22.5 h (P<0.01). There was no change in luteal weight, luteal concentration of progesterone, total number of LH receptors or the number of receptors occupied by LH at 2.5 or 7.5 h when compared to luteal tissue from control ewes. However, each of these parameters had decreased by 22.5 h. The affinity of the receptor for LH did not differ at any of the times studied. These data indicate that progesterone secretion by the corpus luteum after PGF2? administration decreased well before (7.5 h) decreases in the number of occupied or unoccupied receptors for LH could be detected (22.5 h).
650 $aCorpus luteum
650 $aEndocrinology
650 $aEstrus
650 $aLuteinizing hormone
650 $aPharmacology
650 $aPregnancy
650 $aProgesterone
650 $aProstaglandin-F synthase
650 $aReproduction
650 $aSheep
650 $aEndocrinologia
650 $aFisiologia
650 $aOvino
650 $aReprodução
653 $aDrug effects
653 $aReceptors Cell Surface
700 1 $aO'CALLAGHAN, P.
700 1 $aNETT, T. M.
700 1 $aNISWENDER, G. D.
773 $tBiology of Reproduction$gv. 19, n. 5, p. 1010-1013, 1978.
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Embrapa Caprinos e Ovinos (CNPC) |
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| Registros recuperados : 4 | |
| 1. |  | SOUZA, J. R. de; RIBEIRO, B. N.; RAPOSO, T. P.; FIORIN, J. E.; CASTRO, G. S. A.; MAGALHÃES, R. S. Eficiência do fósforo revestido com polímeros na cultura da soja. Acta Iguazu, Cascavel, v. 3, n. 4, p. 1-9, 2014.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: C - 0 |
| Biblioteca(s): Embrapa Amapá. |
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| 2. | | RAPOSO, T. P.; SOUZA, J. R. de; RIBEIRO, B. N.; ROLIM, M. V.; CASTRO, G. S. A. Eficiência da ureia revestida com polímeros, na produtividade de milho safrinha. In: SEMINÁRIO NACIONAL [DE] MILHO SAFRINHA, 12., 2013, Dourados. Estabilidade e produtividade: anais. Brasília, DF: Embrapa; Dourados: Embrapa Agropecuária Oeste, 2013. Editado por: Germani Concenço, Gessi Ceccon. Disponível em: http://www.cpao.embrapa.br/cds/milhosafrinha2013/PDF/61.pdf. Acesso em 18 dez. 2013.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Amapá. |
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| 3. | | RAPOSO, T. P.; MAGALHÃES, R. S.; SOUZA, J. R. de; MINGOTTE, F. L. C.; CASTRO, G. S. A.; CARVALHO, A. Alteração da agregação de um latossolo vermelho-amarelo em função do preparo físico. Science and Technology Innovation in Agronomy, Bebedouro, v. 2, n. 1, p. 72-82, mar. 2018. p. 72-82| Tipo: Artigo em Periódico Indexado |
| Biblioteca(s): Embrapa Territorial. |
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| Registros recuperados : 4 | |
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