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 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
08/11/2023 |
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Autoria: |
BRANDER, W. M.; ROBINSON, T. J. |
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Título: |
Effect of duration of intravenous injection on the response of the spayed ewe to oestradiol benzoate (ODB). |
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Ano de publicação: |
1962 |
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Fonte/Imprenta: |
Journal of Reproduction and Fertility, v. 3, n. 1, p. 64-73, Feb. 1962. |
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DOI: |
10.1530/jrf.0.0030064 |
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Idioma: |
Inglês |
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Conteúdo: |
Osmotic injection pumps have been used to determine time-dose relationships in the response of spayed progesterone-primed ewes to oestrogen. Oestradiol benzoate (ODB) has been injected in propylene glycol directly into the jugular vein over the range 0 to 32 hr. No relationship could be demonstrated between time and total dose in the behavioural and vaginal response, but there was a significant total-dose/response effect. The ED50 of ODB for behavioural oestrus was 23 ug. No dose-response effect could be demonstrated for vaginal changes. The pumps delivered at a linear rate (b = 0·029, ±0·003; y = 0·029 ?0·053, where y = volume in millilitres and x = time in hours), over the time range studied, but were highly variable. It is concluded that the reacting tissues, neural and vaginal, are able to absorb and utilize ODB with an almost equal degree of efficiency if it is given either as a single intravenous injection or as a continuous infusion over many hours. |
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Thesagro: |
Fisiologia; Ovino; Reprodução. |
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Thesaurus Nal: |
Females; Intravenous injection; Pharmacology; Sheep. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 01667naa a2200229 a 4500
001 1519649
005 2023-11-08
008 1962 bl uuuu u00u1 u #d
024 7 $a10.1530/jrf.0.0030064$2DOI
100 1 $aBRANDER, W. M.
245 $aEffect of duration of intravenous injection on the response of the spayed ewe to oestradiol benzoate (ODB).$h[electronic resource]
260 $c1962
520 $aOsmotic injection pumps have been used to determine time-dose relationships in the response of spayed progesterone-primed ewes to oestrogen. Oestradiol benzoate (ODB) has been injected in propylene glycol directly into the jugular vein over the range 0 to 32 hr. No relationship could be demonstrated between time and total dose in the behavioural and vaginal response, but there was a significant total-dose/response effect. The ED50 of ODB for behavioural oestrus was 23 ug. No dose-response effect could be demonstrated for vaginal changes. The pumps delivered at a linear rate (b = 0·029, ±0·003; y = 0·029 ?0·053, where y = volume in millilitres and x = time in hours), over the time range studied, but were highly variable. It is concluded that the reacting tissues, neural and vaginal, are able to absorb and utilize ODB with an almost equal degree of efficiency if it is given either as a single intravenous injection or as a continuous infusion over many hours.
650 $aFemales
650 $aIntravenous injection
650 $aPharmacology
650 $aSheep
650 $aFisiologia
650 $aOvino
650 $aReprodução
700 1 $aROBINSON, T. J.
773 $tJournal of Reproduction and Fertility$gv. 3, n. 1, p. 64-73, Feb. 1962.
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| 3. |  | OLIVEIRA, L. J.; DE ANGELIS, S.; CORSO, I. C.; CAMARGO, T. V. de. Efeito de diversos inseticidas sobre a populacao de percevejo castanho da raiz, em soja - Sapezal, MT. In: WORKSHOP SOBRE PERCEVEJO CASTANHO DA RAIZ, 1999, Londrina. Ata e resumos. Londrina: Embrapa Soja, 1999. p.60. (Embrapa Soja. Documentos, 127).| Biblioteca(s): Embrapa Soja. |
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