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Registro Completo |
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Biblioteca(s): |
Embrapa Amazônia Oriental. |
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Data corrente: |
27/10/2003 |
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Data da última atualização: |
27/10/2003 |
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Autoria: |
GREEN, D.E. (Ed.). |
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Título: |
Currents in biochemical research. |
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Ano de publicação: |
1946 |
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Fonte/Imprenta: |
New York: Interscience, 1946. |
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Páginas: |
486p. |
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Descrição Física: |
il. |
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Idioma: |
Inglês |
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Conteúdo: |
The gene and biochemistry. Viruses. Photosynthesis and the production of organic matter on earth. The bacterial cell. The nutrition and biochemistry of plants. Biological significance of vitamins. Some aspects of vitamin research. Quantitative analysis in biochemistry. Enzymic hydrolysis and synthesis of peptide bonds. Metabolic process patterns. Biochemistry from the standpoint of enzymes. Enzymic mechanisms of carbon dioxide assimilation. Hormones. Fundamentals of oxidation and reduction. Mesomeric concepts in the biological sciences. Viscometry in biochemical investigations. Isotope technique in the study of intermediary metabolism. Mucolytic enzymes. Some aspects of intermediary metabolism. The steroid hormones. Plant hormones and the analysis of growth. Chemical mechanism of nervous action. Some aspects of biochemical antagonism. Chemotherapy: applied cytochemistry. Biochemical aspects of pharmacology. Some biochemical problems posed by a disease of muscle. Physiology and biochemistry. X-ray diffraction and the study of fibrous proteins. Immunochemistry. Social aspects of nutrition. Organization and support of science in the United States. |
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Thesagro: |
Análise Quantitativa; Bioquímica; Célula; Hormônio; Matéria Orgânica; Pesquisa. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01636nam a2200193 a 4500
001 1404129
005 2003-10-27
008 1946 bl uuuu 00u1 u #d
100 1 $aGREEN, D.E. (Ed.).
245 $aCurrents in biochemical research.
260 $aNew York: Interscience$c1946
300 $a486p.$cil.
520 $aThe gene and biochemistry. Viruses. Photosynthesis and the production of organic matter on earth. The bacterial cell. The nutrition and biochemistry of plants. Biological significance of vitamins. Some aspects of vitamin research. Quantitative analysis in biochemistry. Enzymic hydrolysis and synthesis of peptide bonds. Metabolic process patterns. Biochemistry from the standpoint of enzymes. Enzymic mechanisms of carbon dioxide assimilation. Hormones. Fundamentals of oxidation and reduction. Mesomeric concepts in the biological sciences. Viscometry in biochemical investigations. Isotope technique in the study of intermediary metabolism. Mucolytic enzymes. Some aspects of intermediary metabolism. The steroid hormones. Plant hormones and the analysis of growth. Chemical mechanism of nervous action. Some aspects of biochemical antagonism. Chemotherapy: applied cytochemistry. Biochemical aspects of pharmacology. Some biochemical problems posed by a disease of muscle. Physiology and biochemistry. X-ray diffraction and the study of fibrous proteins. Immunochemistry. Social aspects of nutrition. Organization and support of science in the United States.
650 $aAnálise Quantitativa
650 $aBioquímica
650 $aCélula
650 $aHormônio
650 $aMatéria Orgânica
650 $aPesquisa
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Registro original: |
Embrapa Amazônia Oriental (CPATU) |
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Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital. |
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Data corrente: |
21/11/2012 |
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Data da última atualização: |
14/04/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
PROTASIO, A. V.; TSAI, I. J.; BABBAGE, A.; NICHOL, S.; HUNT, M.; ASLETT, M. A.; SILVA, N. de; VELARDE, G. S.; ANDERSON, T. J. C.; CLARK, R. C.; DAVIDSON, C.; DILLON, G. P.; HOLROYD, N. E.; LOVERDE, P. T.; LLOYD, C.; MCQUILLAN, J.; OLIVEIRA, G.; OTTO, T. D.; PARKER-MANUEL, S. J.; QUAIL, M. A.; WILSON, R. A.; ZERLOTINI, A.; DUNNE, D. W.; BERRIMAN, M. |
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Afiliação: |
ANNA V. PROTASIO, Wellcome Trust Sanger Institute; ISHENG J. TSAI, Wellcome Trust Sanger Institute; ANNE BABBAGE, Wellcome Trust Sanger Institute; SARAH NICHOL, Wellcome Trust Sanger Institute; MARTIN HUNT, Wellcome Trust Sanger Institute; MARTIN A. ASLETT, Wellcome Trust Sanger Institute; NISHADI DE SILVA, Wellcome Trust Sanger Institute; GILES S. VELARDE, Wellcome Trust Sanger Institute; TIM J. C. ANDERSON, Texas Biomedical Research Institute; RICHARD C. CLARK, Wellcome Trust Sanger Institute; CLAIRE DAVIDSON, Wellcome Trust Sanger Institute; GARY P. DILLON, Wellcome Trust Sanger Institute; NANCY E. HOLROYD, Wellcome Trust Sanger Institute; PHILIP T. LOVERDE, University of Texas Health Science Center; CHRISTINE LLOYD, Wellcome Trust Sanger Institute; JACQUELLINE MCQUILLAN, Wellcome Trust Sanger Institute; GUILHERME OLIVEIRA, Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz; THOMAS D. OTTO, Wellcome Trust Sanger Institute; SOPHIA J. PARKER-MANUEL, University of York; MICHAEL A. QUAIL, Wellcome Trust Sanger Institute; R. ALAN WILSON, University of York; ADHEMAR ZERLOTINI NETO, CNPTIA; DAVID W. DUNNE, University of Cambridge; MATTHEW BERRIMAN, Wellcome Trust Sanger Institute. |
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Título: |
A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni. |
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Ano de publicação: |
2012 |
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Fonte/Imprenta: |
PLOS Neglected Tropical Diseases, v. 6, n. 1, p. 1-13, Jan. 2012. |
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DOI: |
10.1371/journal.pntd.0001455 |
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Idioma: |
Inglês |
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Conteúdo: |
Schistosomiasis is one of the most prevalent parasitic diseases, affecting millions of people in developing countries. Amongst the human-infective species, Schistosoma mansoni is also the most commonly used in the laboratory and here we present the systematic improvement of its draft genome. We used Sanger capillary and deep-coverage Illumina sequencing from clonal worms to upgrade the highly fragmented draft 380 Mb genome to one with only 885 scaffolds and more than 81% of the bases organised into chromosomes. We have also used transcriptome sequencing (RNA-seq) from four time points in the parasite?s life cycle to refine gene predictions and profile their expression. More than 45% of predicted genes have been extensively modified and the total number has been reduced from 11,807 to 10,852. Using the new version of the genome, we identified trans-splicing events occurring in at least 11% of genes and identified clear cases where it is used to resolve polycistronic transcripts. We have produced a high-resolution map of temporal changes in expression for 9,535 genes, covering an unprecedented dynamic range for this organism. All of these data have been consolidated into a searchable format within the GeneDB (www.genedb.org) and SchistoDB (www.schistodb.net) databases. With further transcriptional profiling and genome sequencing increasingly accessible, the upgraded genome will form a fundamental dataset to underpin further advances in schistosome research. |
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Thesaurus NAL: |
Schistosoma. |
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Categoria do assunto: |
-- |
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URL: |
https://www.alice.cnptia.embrapa.br/alice/bitstream/doc/940202/1/journal.pntd.0001455.pdf
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Marc: |
LEADER 02660naa a2200421 a 4500
001 1940202
005 2020-04-14
008 2012 bl uuuu u00u1 u #d
024 7 $a10.1371/journal.pntd.0001455$2DOI
100 1 $aPROTASIO, A. V.
245 $aA systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni.$h[electronic resource]
260 $c2012
520 $aSchistosomiasis is one of the most prevalent parasitic diseases, affecting millions of people in developing countries. Amongst the human-infective species, Schistosoma mansoni is also the most commonly used in the laboratory and here we present the systematic improvement of its draft genome. We used Sanger capillary and deep-coverage Illumina sequencing from clonal worms to upgrade the highly fragmented draft 380 Mb genome to one with only 885 scaffolds and more than 81% of the bases organised into chromosomes. We have also used transcriptome sequencing (RNA-seq) from four time points in the parasite?s life cycle to refine gene predictions and profile their expression. More than 45% of predicted genes have been extensively modified and the total number has been reduced from 11,807 to 10,852. Using the new version of the genome, we identified trans-splicing events occurring in at least 11% of genes and identified clear cases where it is used to resolve polycistronic transcripts. We have produced a high-resolution map of temporal changes in expression for 9,535 genes, covering an unprecedented dynamic range for this organism. All of these data have been consolidated into a searchable format within the GeneDB (www.genedb.org) and SchistoDB (www.schistodb.net) databases. With further transcriptional profiling and genome sequencing increasingly accessible, the upgraded genome will form a fundamental dataset to underpin further advances in schistosome research.
650 $aSchistosoma
700 1 $aTSAI, I. J.
700 1 $aBABBAGE, A.
700 1 $aNICHOL, S.
700 1 $aHUNT, M.
700 1 $aASLETT, M. A.
700 1 $aSILVA, N. de
700 1 $aVELARDE, G. S.
700 1 $aANDERSON, T. J. C.
700 1 $aCLARK, R. C.
700 1 $aDAVIDSON, C.
700 1 $aDILLON, G. P.
700 1 $aHOLROYD, N. E.
700 1 $aLOVERDE, P. T.
700 1 $aLLOYD, C.
700 1 $aMCQUILLAN, J.
700 1 $aOLIVEIRA, G.
700 1 $aOTTO, T. D.
700 1 $aPARKER-MANUEL, S. J.
700 1 $aQUAIL, M. A.
700 1 $aWILSON, R. A.
700 1 $aZERLOTINI, A.
700 1 $aDUNNE, D. W.
700 1 $aBERRIMAN, M.
773 $tPLOS Neglected Tropical Diseases$gv. 6, n. 1, p. 1-13, Jan. 2012.
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Embrapa Agricultura Digital (CNPTIA) |
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