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Registro Completo |
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Biblioteca(s): |
Embrapa Amazônia Oriental. |
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Data corrente: |
21/06/2001 |
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Data da última atualização: |
06/12/2022 |
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Autoria: |
ISHIBASHI, M.; ODA, H.; MITAMURA, M.; OKUYAMA, E.; KOMIYAMA, K.; KAWAGUCHI, K.; WATANABE, T.; ALVES, S. de M.; MACKAWA, T.; OHTSUKI, K. |
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Afiliação: |
MASAMI ISHIBASHI, CHIBA UNIVERSITY; HIROKO ODA, CHIBA UNIVERSITY; MANA MITAMURA, CHIBA UNIVERSITY; EMI OKUYAMA, CHIBA UNIVERSITY; KANKI KOMIYAMA, KITASATO INSTITUTE; KIICHIRO KAWAGUCHI, KITASATO UNIVERSITY; TAKASHI WATANABE, KITASATO UNIVERSITY; SERGIO DE MELLO ALVES, CPATU; TOSHIRO MACKAWA, KITASATO UNIVERSITY; KENZO OHTSUKI, KITASATO UNIVERSITY. |
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Título: |
Casein Kinase II inhibitors isolated from two brazilian plants hymenaea parvifolia and wulffia baccata. |
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Ano de publicação: |
1999 |
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Fonte/Imprenta: |
Bioorganic & Medicinal Chemistry Letters, v. 9, n. 15, p. 2157-2160, Aug. 1999. |
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Descrição Física: |
il. |
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DOI: |
http://dx.doi.org/10.1016/S0960-894X(99)00351-0 |
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Idioma: |
Inglês |
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Conteúdo: |
Two dihydroflavonol rhamnosides (1 and 2) isolated from the bark of Hymenaea parvifolia and two pentacyclic triterpenoids (3 and 6) obtained from the leaves of Wulffia baccata have been found to exhibit inhibitory effects of casein kinase II (CK-II) dose-dependently, suggesting that at higher doses more than 10 ?M, these four compounds may act as potent CK-II suppressors of the CK-II mediated activation of 60S acidic ribosomal P proteins in vitro. |
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Palavras-Chave: |
Antagonism; Drug plants; Jutai; Wulffia baccata. |
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Thesagro: |
Antagonismo; Cambara; Hymenaea Parvifolia; Planta Medicinal. |
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Categoria do assunto: |
-- |
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Marc: |
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001 1400481
005 2022-12-06
008 1999 bl uuuu u00u1 u #d
024 7 $ahttp://dx.doi.org/10.1016/S0960-894X(99)00351-0$2DOI
100 1 $aISHIBASHI, M.
245 $aCasein Kinase II inhibitors isolated from two brazilian plants hymenaea parvifolia and wulffia baccata.$h[electronic resource]
260 $c1999
300 $cil.
520 $aTwo dihydroflavonol rhamnosides (1 and 2) isolated from the bark of Hymenaea parvifolia and two pentacyclic triterpenoids (3 and 6) obtained from the leaves of Wulffia baccata have been found to exhibit inhibitory effects of casein kinase II (CK-II) dose-dependently, suggesting that at higher doses more than 10 ?M, these four compounds may act as potent CK-II suppressors of the CK-II mediated activation of 60S acidic ribosomal P proteins in vitro.
650 $aAntagonismo
650 $aCambara
650 $aHymenaea Parvifolia
650 $aPlanta Medicinal
653 $aAntagonism
653 $aDrug plants
653 $aJutai
653 $aWulffia baccata
700 1 $aODA, H.
700 1 $aMITAMURA, M.
700 1 $aOKUYAMA, E.
700 1 $aKOMIYAMA, K.
700 1 $aKAWAGUCHI, K.
700 1 $aWATANABE, T.
700 1 $aALVES, S. de M.
700 1 $aMACKAWA, T.
700 1 $aOHTSUKI, K.
773 $tBioorganic & Medicinal Chemistry Letters$gv. 9, n. 15, p. 2157-2160, Aug. 1999.
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Registro original: |
Embrapa Amazônia Oriental (CPATU) |
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