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Registro Completo |
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Biblioteca(s): |
Embrapa Instrumentação. |
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Data corrente: |
22/12/1999 |
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Data da última atualização: |
22/12/1999 |
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Autoria: |
CRAIK, D. J. ed. |
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Afiliação: |
Centre for Drug Design and Development, University of Queensland. |
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Título: |
NMR in drug design. |
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Ano de publicação: |
1996 |
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Fonte/Imprenta: |
Boca Raton: CRC, 1996. |
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Páginas: |
476p. il. |
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ISBN: |
0-8493-7824-9 |
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Idioma: |
Inglês |
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Conteúdo: |
Drug design and discovery: where next? The role of NMR in drug design and development. Studies of drug-receptor interactions by NMR: theory and applications. Protein structure determination using NMR spectroscopy. Conformational analysis of drug molecules. Conformational analysis of peptides: application to drug design. Protein-ligand interactions: examples in drug design. NMR sutdies of ligand binding to dihydrofolate reductase and their application in drug design. Studies of drug-calmodulin binding using isotopically labelled protein. Flexibility and function in the HIV-1 protease. DNA as a target for drug action: complexes of intercalating antibiotics. Drug binding to the minor groove of DNA. |
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Palavras-Chave: |
Drogas; Espectroscopia; Instrumentacao; NMR; Nuclear magnetic resonance; Projeto; Ressonancia magnetica nuclear; RMN; Technique; Tecnica. |
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Thesaurus Nal: |
design; drugs; instrumentation; spectroscopy. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01400nam a2200301 a 4500
001 1025767
005 1999-12-22
008 1996 bl uuuu 00u1 u #d
020 $a0-8493-7824-9
100 1 $aCRAIK, D. J. ed.
245 $aNMR in drug design.
260 $aBoca Raton: CRC$c1996
300 $a476p. il.
520 $aDrug design and discovery: where next? The role of NMR in drug design and development. Studies of drug-receptor interactions by NMR: theory and applications. Protein structure determination using NMR spectroscopy. Conformational analysis of drug molecules. Conformational analysis of peptides: application to drug design. Protein-ligand interactions: examples in drug design. NMR sutdies of ligand binding to dihydrofolate reductase and their application in drug design. Studies of drug-calmodulin binding using isotopically labelled protein. Flexibility and function in the HIV-1 protease. DNA as a target for drug action: complexes of intercalating antibiotics. Drug binding to the minor groove of DNA.
650 $adesign
650 $adrugs
650 $ainstrumentation
650 $aspectroscopy
653 $aDrogas
653 $aEspectroscopia
653 $aInstrumentacao
653 $aNMR
653 $aNuclear magnetic resonance
653 $aProjeto
653 $aRessonancia magnetica nuclear
653 $aRMN
653 $aTechnique
653 $aTecnica
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Registro original: |
Embrapa Instrumentação (CNPDIA) |
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| 1. |  | GALANTE, P.; CAMPOS, G. A. A.; MOSER, J. C. G.; MARTINS, D. B.; CABRERA, M. P. dos S.; RANGEL, M.; COELHO, L. C.; SIMON, K. S.; AMADO, V. M.; MULLER, J. de A. I.; KOEHBACH, J.; LOHMAN, R.-J.; CABOT, P. J.; VETTER, I.; CRAIK, D. J.; TOFFOLI-KADRI, M. C.; MONGE-FUENTES, V.; GOULART, J. T.; SCHWARTZ, E. F.; SILVA, L. P. da; BOCCA, A. L.; MORTARI, M. R. Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom. Scientific Reports, v. 13, 2023. Article number: 12491. Na publicação: Luciano P. Silva.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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