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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
15/01/2025 |
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Data da última atualização: |
10/02/2025 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
SCHEPANSKI, N.; COSTA, F. S.; MACHADO, E. F. M.; PACHECO, M. N.; AMARAL, C. D. B.; MACHADO, R. C.; NOGUEIRA, A. R. de A.; BRANCHER, J. A.; SASSI, L. M.; ARAUJO, M. R. DE. |
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Afiliação: |
NATALIA SCHEPANSKI, UNIVERSIDADE FEDERAL DO PARANÁ; FLORIATAN SANTOS COSTA, UNIVERSIDADE FEDERAL DO PARANÁ; EDINA FERNANDA MARTINS MACHADO, UNIVERSIDADE FEDERAL DO PARANÁ; MILENA NUNES PACHECO, UNIVERSIDADE FEDERAL DO PARANÁ; CLARICE D. B. AMARAL, UNIVERSIDADE FEDERAL DO PARANÁ; RAQUEL C. MACHADO; ANA RITA DE ARAUJO NOGUEIRA, CPPSE; JOÃO ARMANDO BRANCHER, PONTIFÍCIA UNIVERSIDADE CATÓLICA DO PARANÁ; LAURINDO MOACIR SASSI, ERASTO GAERTNER HOSPITAL; MELISSA RODRIGUES DE ARAUJO, UNIVERSIDADE FEDERAL DO PARANÁ. |
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Título: |
Evaluation of photobiomodulation therapy (PBMT) on salivary flow and composition in head and neck cancer patients undergoing radiation therapy. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, v. 137, n. 3, p. 253-263, mar. 2024. |
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DOI: |
https://doi.org/10.1016/j.oooo.2023.11.007 |
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Idioma: |
Inglês |
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Conteúdo: |
Objective Assess the impact of photobiomodulation therapy (PBMT) on xerostomia, salivary flow rate (SFR) and composition in patients undergoing radiotherapy (RT) for head and neck cancer (HNC). Study Design Thirty patients undergoing RT (65 Gy) for HNC were enrolled. Saliva and xerostomia evaluations collected pre- and post-PBMT-RT. PBMT involved irradiation of extra and intraoral points, 15-20 sessions, 2-3 times/week. SFR, trace elements, total protein, alkaline phosphatase, xerostomia, and pH were analyzed. Results The average age was 60.7 years. After treatment, there was not a significant reduction in SFR and there was no difference on xerostomia. Significant reductions in Al, Cd, Fe, Ni, P, and Sb concentrations were observed, along with a significant increase in Mg concentration. Sample data were organized into 3 groups based on a self-organizing map. Low concentrations of Al, As, Co, Cr, Cu, Fe, Mn, Mo, S, Sr, and Zn were the primary discriminatory factors for group A, while group B consisted of post-PBMT-RT samples with high concentrations of Ca, K, Mg, Na, and S. Conclusions PBMT prevented a significant reduction in SFR and xerostomia induced by radiation therapy. These findings suggest that PBMT prevents salivary gland damage minimizing the decline in salivary flow. |
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Palavras-Chave: |
Head and neck cancer; Hyposalivation; Photobiomodulation therapy; Salivary constituents; Salivary flow rate; Salivary gland damage; Total protein; Undergoing radiotherapy; Xerostomia. |
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Thesaurus Nal: |
Alkaline phosphatase; Quality of life; Radiotherapy. |
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Categoria do assunto: |
W Química e Física |
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Marc: |
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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