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Registro Completo |
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
27/06/2024 |
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Data da última atualização: |
27/06/2024 |
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Tipo da produção científica: |
Capítulo em Livro Técnico-Científico |
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Autoria: |
FEDDERN, V.; BASTOS, A. P. A.; GRESSLER, V.; MARQUES, D. M. C.; FERREIRA, F. C.; RODRIGUES, C. A. V.; TEIXEIRA, M. V. T.; SILVA, C. L. de. |
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Afiliação: |
VIVIAN FEDDERN, CPACT; ANA PAULA ALMEIDA BASTOS, CNPSA; VANESSA GRESSLER, CNPSA; DIANA M. C. MARQUES, UNIVERSIDADE DE LISBOA; FREDERICO C. FERREIRA, UNIVERSIDADE DE LISBOA; CARLOS ANDRÉ VITORINO RODRIGUES, UNIVERSIDADE DE LISBOA; MARCUS VINICIUS TELLES TEIXEIRA, UNIVERSIDADE DE LISBOA; CAMILA LUNA DA SILVA, CAMPUS TECNOLÓGICO DO INMETRO. |
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Título: |
Cell lines for cultivated meat production. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
In: SOCCOL, C. R.; MOLENTO, C. F. M.; REIS, G. G.; KARP, S. G. (ed.). Cultivated meat: technologies, commercialization and challenges. Cham, Switzerland: Springer, 2024. p. 29-54. |
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DOI: |
https://doi.org/10.1007/978-3-031-55968-6_3 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Cellular agriculture is an emerging field that aims to provide a more sustainable alternative for the production of animal-derived products, without the need to sacrifice animals. Cultivated meat is one of the main products of cell agriculture and consists in the production of meat from animal cell cultures in a growth medium. A cell line with reproducible and consistent properties is essential for any bioprocess and is crucial for the production of cultivated meat. Developing cell lines from farm animal sources with the necessary proliferative capacity and differentiation potential is a critical technical component that must be optimized to enable scale-up and commercialization of cultivated meat. There are two major strategies to establish these cell lines: (1) using a sample of the tissue of interest (primary cell sources), with further isolation of the muscle-resident progenitor cells; and (2) by the use of pluripotent cell sources, like embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), which have the capability to differentiate toward muscle-resident progenitor cells. As muscle is composed of different tissue types (nerves, blood vessels, adipose and connective tissue), the production of cultured meat requires the use of progenitor cells with the capability to differentiate into myocytes, adipocytes, fibroblasts, chondrocytes, and hematopoietic cells. This chapter will cover potential strategies for cell line development and their advantages and disadvantages, regarding the isolation protocol of cultivated fish, chicken and mammalian cells. In addition, sampling techniques, cell line characterization, conservation and quality control, as well as challenges and future prospects in the field will be addressed. MenosAbstract: Cellular agriculture is an emerging field that aims to provide a more sustainable alternative for the production of animal-derived products, without the need to sacrifice animals. Cultivated meat is one of the main products of cell agriculture and consists in the production of meat from animal cell cultures in a growth medium. A cell line with reproducible and consistent properties is essential for any bioprocess and is crucial for the production of cultivated meat. Developing cell lines from farm animal sources with the necessary proliferative capacity and differentiation potential is a critical technical component that must be optimized to enable scale-up and commercialization of cultivated meat. There are two major strategies to establish these cell lines: (1) using a sample of the tissue of interest (primary cell sources), with further isolation of the muscle-resident progenitor cells; and (2) by the use of pluripotent cell sources, like embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), which have the capability to differentiate toward muscle-resident progenitor cells. As muscle is composed of different tissue types (nerves, blood vessels, adipose and connective tissue), the production of cultured meat requires the use of progenitor cells with the capability to differentiate into myocytes, adipocytes, fibroblasts, chondrocytes, and hematopoietic cells. This chapter will cover potential strategies for cell line development and their advanta... Mostrar Tudo |
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Palavras-Chave: |
Carne cultivada; Células de mamíferos cultivadas; Cultivated chicken; Cultivated fsh; Cultivated mammalian cells; Cultivated Meat; Frango cultivado; Muscle cells; Peixe cultivado; Satellite cells. |
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Categoria do assunto: |
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Marc: |
LEADER 02885naa a2200337 a 4500
001 2165213
005 2024-06-27
008 2024 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1007/978-3-031-55968-6_3$2DOI
100 1 $aFEDDERN, V.
245 $aCell lines for cultivated meat production.$h[electronic resource]
260 $c2024
520 $aAbstract: Cellular agriculture is an emerging field that aims to provide a more sustainable alternative for the production of animal-derived products, without the need to sacrifice animals. Cultivated meat is one of the main products of cell agriculture and consists in the production of meat from animal cell cultures in a growth medium. A cell line with reproducible and consistent properties is essential for any bioprocess and is crucial for the production of cultivated meat. Developing cell lines from farm animal sources with the necessary proliferative capacity and differentiation potential is a critical technical component that must be optimized to enable scale-up and commercialization of cultivated meat. There are two major strategies to establish these cell lines: (1) using a sample of the tissue of interest (primary cell sources), with further isolation of the muscle-resident progenitor cells; and (2) by the use of pluripotent cell sources, like embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), which have the capability to differentiate toward muscle-resident progenitor cells. As muscle is composed of different tissue types (nerves, blood vessels, adipose and connective tissue), the production of cultured meat requires the use of progenitor cells with the capability to differentiate into myocytes, adipocytes, fibroblasts, chondrocytes, and hematopoietic cells. This chapter will cover potential strategies for cell line development and their advantages and disadvantages, regarding the isolation protocol of cultivated fish, chicken and mammalian cells. In addition, sampling techniques, cell line characterization, conservation and quality control, as well as challenges and future prospects in the field will be addressed.
653 $aCarne cultivada
653 $aCélulas de mamíferos cultivadas
653 $aCultivated chicken
653 $aCultivated fsh
653 $aCultivated mammalian cells
653 $aCultivated Meat
653 $aFrango cultivado
653 $aMuscle cells
653 $aPeixe cultivado
653 $aSatellite cells
700 1 $aBASTOS, A. P. A.
700 1 $aGRESSLER, V.
700 1 $aMARQUES, D. M. C.
700 1 $aFERREIRA, F. C.
700 1 $aRODRIGUES, C. A. V.
700 1 $aTEIXEIRA, M. V. T.
700 1 $aSILVA, C. L. de
773 $tIn: SOCCOL, C. R.; MOLENTO, C. F. M.; REIS, G. G.; KARP, S. G. (ed.). Cultivated meat: technologies, commercialization and challenges. Cham, Switzerland: Springer, 2024. p. 29-54.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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