| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com rosangela.lacerda@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Gado de Leite. |
|
Data corrente: |
21/04/2024 |
|
Data da última atualização: |
23/04/2024 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
ONORATO, G. de C.; AMARAL, D. L. A. S. do; OLIVEIRA, L. F. C. de; BRANDAO, H. de M.; MUNK, M. |
|
Afiliação: |
GEOVANA DE CARVALHO ONORATO, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; DANIELLE LUCIANA AURORA SOARES DO AMARAL, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; LUIZ FERNANDO CAPPA DE OLIVEIRA, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; HUMBERTO DE MELLO BRANDAO, CNPGL; MICHELE MUNK, UNIVERSIDADE FEDERAL DE JUIZ DE FORA. |
|
Título: |
Barium titanate nanoparticles exhibit cytocompatibility in cultured bovine fibroblasts: a model for dermal exposure. |
|
Ano de publicação: |
2024 |
|
Fonte/Imprenta: |
Current Journal of Applied Science and Technology, v. 43, n. 5, article CJAST.115461, 2024. |
|
DOI: |
https://doi.org/10.9734/cjast/2024/v43i54372 |
|
Idioma: |
Inglês |
|
Conteúdo: |
The emergence of barium titanate nanoparticles (BaTiO3 NPs) represents an advancement in various fields such as technology, health, and agribusiness. However, increased production heightens the risk of their dispersion into the environment, thereby raising concerns about potential exposure to animals and humans, including the risk of dermal exposure. This study explores the chemical-physical properties of BaTiO3 NPs and their cytocompatibility using a bovine fibroblast cell model. The size and Zeta potential of the NPs were analyzed using scanning electron microscopy and dynamic light scattering technique. Raman spectroscopy was used to characterize the composition of the BaTiO3 NPs. Bovine fibroblasts were exposed in vitro to NPs (0.1 to 100 μg mL-1 ) for 24 hours to evaluate the cytocompatibility using the Thiazolyl Blue Tetrazolium Bromide assay and Trypan Blue exclusion test. The data were evaluated by analysis of variance and the means compared by the Tukey test. Scanning electron microscopy revealed that BaTiO3 NPs measured approximately 100 nm. Dynamic light scattering analysis indicated a hydrodynamic size of 149.27 nm with a polydispersion index of 0.37, and the Zeta potential was -13mV. Raman spectroscopy analysis highlighted the cubic phase of BaTiO3 NPs. Cytotoxicity tests demonstrated that BaTiO3 NPs did not affect cell viability, with 10 μg mL-1 resulting in enhanced cell proliferation. Overall, these findings underscore the non-toxic characteristics of BaTiO3 NPs in fibroblast cells, positioning them as promising and cytocompatible nanomaterials. MenosThe emergence of barium titanate nanoparticles (BaTiO3 NPs) represents an advancement in various fields such as technology, health, and agribusiness. However, increased production heightens the risk of their dispersion into the environment, thereby raising concerns about potential exposure to animals and humans, including the risk of dermal exposure. This study explores the chemical-physical properties of BaTiO3 NPs and their cytocompatibility using a bovine fibroblast cell model. The size and Zeta potential of the NPs were analyzed using scanning electron microscopy and dynamic light scattering technique. Raman spectroscopy was used to characterize the composition of the BaTiO3 NPs. Bovine fibroblasts were exposed in vitro to NPs (0.1 to 100 μg mL-1 ) for 24 hours to evaluate the cytocompatibility using the Thiazolyl Blue Tetrazolium Bromide assay and Trypan Blue exclusion test. The data were evaluated by analysis of variance and the means compared by the Tukey test. Scanning electron microscopy revealed that BaTiO3 NPs measured approximately 100 nm. Dynamic light scattering analysis indicated a hydrodynamic size of 149.27 nm with a polydispersion index of 0.37, and the Zeta potential was -13mV. Raman spectroscopy analysis highlighted the cubic phase of BaTiO3 NPs. Cytotoxicity tests demonstrated that BaTiO3 NPs did not affect cell viability, with 10 μg mL-1 resulting in enhanced cell proliferation. Overall, these findings underscore the non-toxic characteristics of BaTiO3 ... Mostrar Tudo |
|
Palavras-Chave: |
Fibroblasto bovino; Modelos in vitro; Nanomaterial; Nanomaterial cerâmico; Piezoeletricidade; Titanato. |
|
Thesagro: |
Bário. |
|
Categoria do assunto: |
W Química e Física |
|
Marc: |
LEADER 02467naa a2200265 a 4500
001 2163766
005 2024-04-23
008 2024 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.9734/cjast/2024/v43i54372$2DOI
100 1 $aONORATO, G. de C.
245 $aBarium titanate nanoparticles exhibit cytocompatibility in cultured bovine fibroblasts$ba model for dermal exposure.$h[electronic resource]
260 $c2024
520 $aThe emergence of barium titanate nanoparticles (BaTiO3 NPs) represents an advancement in various fields such as technology, health, and agribusiness. However, increased production heightens the risk of their dispersion into the environment, thereby raising concerns about potential exposure to animals and humans, including the risk of dermal exposure. This study explores the chemical-physical properties of BaTiO3 NPs and their cytocompatibility using a bovine fibroblast cell model. The size and Zeta potential of the NPs were analyzed using scanning electron microscopy and dynamic light scattering technique. Raman spectroscopy was used to characterize the composition of the BaTiO3 NPs. Bovine fibroblasts were exposed in vitro to NPs (0.1 to 100 μg mL-1 ) for 24 hours to evaluate the cytocompatibility using the Thiazolyl Blue Tetrazolium Bromide assay and Trypan Blue exclusion test. The data were evaluated by analysis of variance and the means compared by the Tukey test. Scanning electron microscopy revealed that BaTiO3 NPs measured approximately 100 nm. Dynamic light scattering analysis indicated a hydrodynamic size of 149.27 nm with a polydispersion index of 0.37, and the Zeta potential was -13mV. Raman spectroscopy analysis highlighted the cubic phase of BaTiO3 NPs. Cytotoxicity tests demonstrated that BaTiO3 NPs did not affect cell viability, with 10 μg mL-1 resulting in enhanced cell proliferation. Overall, these findings underscore the non-toxic characteristics of BaTiO3 NPs in fibroblast cells, positioning them as promising and cytocompatible nanomaterials.
650 $aBário
653 $aFibroblasto bovino
653 $aModelos in vitro
653 $aNanomaterial
653 $aNanomaterial cerâmico
653 $aPiezoeletricidade
653 $aTitanato
700 1 $aAMARAL, D. L. A. S. do
700 1 $aOLIVEIRA, L. F. C. de
700 1 $aBRANDAO, H. de M.
700 1 $aMUNK, M.
773 $tCurrent Journal of Applied Science and Technology$gv. 43, n. 5, article CJAST.115461, 2024.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Gado de Leite (CNPGL) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 11 | |
| 2. |  | BANDEIRA NETO, N. C.; SALGADO, C. M.; NASCIMENTO, W. M. O. do. Época e genótipo para enxertia por garfagem em castanheira-do-brasil. In: SEMINÁRIO DE INICIAÇÃO CIENTÍFICA DA EMBRAPA AMAZÔNIA ORIENTAL, 25., 2022, Belém, PA. Anais... Belém, PA: Embrapa Amazônia Oriental, 2023. p. 60-61. (Embrapa Amazônia Oriental. Eventos técnicos & científicos, 1).| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Amazônia Oriental. |
|    |
| 5. | | NASCIMENTO, W. M. O. do; TAVARES, R. F. de M.; BANDEIRA NETO, N. C.; RAMOS FILHO, F. L. de S. Alporquia em plantas de camucamuzeiro. In: SILVA-MATOS, R. R. S. da; LOPES, J. A.; FERREIRA, N. R. S. (org.). Ensino, pesquisa e inovação em botânica 3. Ponta Grossa: Atena, 2023. Cap. 3, p. 20-29.| Tipo: Capítulo em Livro Técnico-Científico |
| Biblioteca(s): Embrapa Amazônia Oriental. |
| |
| 8. | | NASCIMENTO, W. M. O. do; SALGADO, C. M.; BANDEIRA NETO, N. C.; SOUZA, O. T.; RAMOS FILHO, F. L. de S. Efeito do genotipo sobre a enxertia por garfagem em castanheira-do-brasil. In: CONGRESSO BRASILEIRO DE FRUTICULTURA, 27.; ENCONTRO NACIONAL SOBRE FRUTICULTURA DE CLIMA TEMPERADO, 17., 2022, Florianópolis, SC. Livro de anais. Florianópolis, SC: Epagri, 2022. p. 1705-1708.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Amazônia Oriental. |
| |
| 11. | | NASCIMENTO, W. M. O. do; BANDEIRA NETO, N. C.; RAMOS FILHO, F. L. de S.; SOUZA, O. T. de; SALGADO, C. M. Porta-enxerto para castanheira-do-brasil. In: SEMINÁRIO DE DESENVOLVIMENTO SUSTENTÁVEL, COOPERATIVISMO E ECONOMIA SOLIDÁRIA, 15., 2023, Castanhal. Anais... [S.l.]: Even3; Castanhal: Instituto Federal de Educação, Ciência e Tecnologia do Pará, 2023. XV SICOOPES.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Amazônia Oriental. |
| |
| Registros recuperados : 11 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
