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Registro Completo |
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Biblioteca(s): |
Embrapa Instrumentação. |
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Data corrente: |
11/01/2024 |
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Data da última atualização: |
11/06/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
SANTOS, F. V. dos; SIQUEIRA, R. L.; RAMOS, L. de M.; YOSHIOKA, S. A.; BRANCIFORTI, M. C.; CORREA, D. S. |
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Afiliação: |
FRANCISCO VIEIRA DOS SANTOS, UNIVERSITY OF SÃO PAULO (USP); RENATO LUIZ SIQUEIRA, FEDERAL UNIVERSITY OF SAO CARLOS (UFSCAR); LUCAS DE MORAIS RAMOS, UNIVERSITY OF SAO PAULO (USP); SÉRGIO AKINOBU YOSHIOKA, UNIVERSITY OF SAO PAULO (USP); MÁRCIA CRISTINA BRANCIFORTI, UNIVERSITY OF SAO PAULO (USP); DANIEL SOUZA CORREA, CNPDIA. |
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Título: |
Silk fibroin-derived electrospun materials for biomedical applications: A review. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
International Journal of Biological Macromolecules, v. 254, 127641, 2024. |
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Páginas: |
34 p. |
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ISSN: |
0141-8130 |
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DOI: |
https://doi.org/10.1016/j.ijbiomac.2023.127641 |
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Idioma: |
Inglês |
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Conteúdo: |
Electrospinning is a versatile technique for fabricating polymeric fibers with diameters ranging from micro- to nanoscale, exhibiting multiple morphologies and arrangements. By combining silk fibroin (SF) with synthetic and/or natural polymers, electrospun materials with outstanding biological, chemical, electrical, physical, mechanical, and optical properties can be achieved, fulfilling the evolving biomedical demands. This review highlights the remarkable versatility of SF-derived electrospun materials, specifically focusing on their application in tissue regeneration (including cartilage, cornea, nerves, blood vessels, bones, and skin), disease treatment (such as cancer and diabetes), and the development of controlled drug delivery systems. Additionally, we explore the potential future trends in utilizing these nanofibrous materials for creating intelligent biomaterials, incorporating biosensors and wearable sensors for monitoring human health, and also discuss the bottlenecks for its widespread use. This comprehensive overview illuminates the significant impact and exciting prospects of SF-derived electrospun materials in advancing biomedical research and applications. |
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Palavras-Chave: |
Biomaterials; Electrospinning; Regenerative medicine; Silk fibroin. |
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Categoria do assunto: |
-- |
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Marc: |
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022 $a0141-8130
024 7 $ahttps://doi.org/10.1016/j.ijbiomac.2023.127641$2DOI
100 1 $aSANTOS, F. V. dos
245 $aSilk fibroin-derived electrospun materials for biomedical applications$bA review.$h[electronic resource]
260 $c2024
300 $a34 p.
520 $aElectrospinning is a versatile technique for fabricating polymeric fibers with diameters ranging from micro- to nanoscale, exhibiting multiple morphologies and arrangements. By combining silk fibroin (SF) with synthetic and/or natural polymers, electrospun materials with outstanding biological, chemical, electrical, physical, mechanical, and optical properties can be achieved, fulfilling the evolving biomedical demands. This review highlights the remarkable versatility of SF-derived electrospun materials, specifically focusing on their application in tissue regeneration (including cartilage, cornea, nerves, blood vessels, bones, and skin), disease treatment (such as cancer and diabetes), and the development of controlled drug delivery systems. Additionally, we explore the potential future trends in utilizing these nanofibrous materials for creating intelligent biomaterials, incorporating biosensors and wearable sensors for monitoring human health, and also discuss the bottlenecks for its widespread use. This comprehensive overview illuminates the significant impact and exciting prospects of SF-derived electrospun materials in advancing biomedical research and applications.
653 $aBiomaterials
653 $aElectrospinning
653 $aRegenerative medicine
653 $aSilk fibroin
700 1 $aSIQUEIRA, R. L.
700 1 $aRAMOS, L. de M.
700 1 $aYOSHIOKA, S. A.
700 1 $aBRANCIFORTI, M. C.
700 1 $aCORREA, D. S.
773 $tInternational Journal of Biological Macromolecules$gv. 254, 127641, 2024.
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Registro original: |
Embrapa Instrumentação (CNPDIA) |
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