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Registro Completo |
Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
Data corrente: |
03/05/2022 |
Data da última atualização: |
10/10/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
MONTENEGRO, J.; FREITAS-SILVA, O.; TEODORO, A. J. |
Afiliação: |
JULIA MONTENEGRO, UNIRIO; OTNIEL FREITAS SILVA, CTAA; ANDERSON JUNGER TEODORO, UNIRIO. |
Título: |
Molecular Mechanisms of Coffee on Prostate Cancer Prevention. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Biomed Research International, D 3254420, p. 1-12, 2022. |
DOI: |
https://doi.org/10.1155/2022/3254420 |
Idioma: |
Inglês |
Notas: |
Review Article. |
Conteúdo: |
Prostate cancer (PCa) is one of the most common types of cancer among men, and coffee is associated with a reduced risk of developing PCa. Therefore, we aim to review possible coffee molecular mechanisms that contribute to PCa prevention. Coffee has an important antioxidant capacity that reduces oxidative stress, leading to a reduced mutation in cells. Beyond direct antioxidant activity, coffee stimulates phase II enzymatic activity, which is related to the detoxification of reactive metabolites. The anti-inflammatory effects of coffee reduce tissue damage related to PCa development. Coffee induces autophagy, regulates the NF-κB pathway, and reduces the expression of iNOS and inflammatory mediators, such as TNF-α, IL-6, IL-8, and CRP. Also, coffee modulates transcriptional factors and pathways. It has been shown that coffee increases testosterone and reduces sex hormone-binding globulin, estrogen, and prostate-specific antigen. Coffee also enhances insulin resistance and glucose metabolism. All these effects may contribute to protection against PCa development. |
Thesaurus Nal: |
Food technology. |
Categoria do assunto: |
-- |
Marc: |
LEADER 01631naa a2200181 a 4500 001 2142603 005 2022-10-10 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1155/2022/3254420$2DOI 100 1 $aMONTENEGRO, J. 245 $aMolecular Mechanisms of Coffee on Prostate Cancer Prevention.$h[electronic resource] 260 $c2022 500 $aReview Article. 520 $aProstate cancer (PCa) is one of the most common types of cancer among men, and coffee is associated with a reduced risk of developing PCa. Therefore, we aim to review possible coffee molecular mechanisms that contribute to PCa prevention. Coffee has an important antioxidant capacity that reduces oxidative stress, leading to a reduced mutation in cells. Beyond direct antioxidant activity, coffee stimulates phase II enzymatic activity, which is related to the detoxification of reactive metabolites. The anti-inflammatory effects of coffee reduce tissue damage related to PCa development. Coffee induces autophagy, regulates the NF-κB pathway, and reduces the expression of iNOS and inflammatory mediators, such as TNF-α, IL-6, IL-8, and CRP. Also, coffee modulates transcriptional factors and pathways. It has been shown that coffee increases testosterone and reduces sex hormone-binding globulin, estrogen, and prostate-specific antigen. Coffee also enhances insulin resistance and glucose metabolism. All these effects may contribute to protection against PCa development. 650 $aFood technology 700 1 $aFREITAS-SILVA, O. 700 1 $aTEODORO, A. J. 773 $tBiomed Research International, D 3254420, p. 1-12, 2022.
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Embrapa Agroindústria de Alimentos (CTAA) |
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Registro Completo
Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
Data corrente: |
02/12/2016 |
Data da última atualização: |
02/12/2016 |
Tipo da produção científica: |
Resumo em Anais de Congresso |
Autoria: |
GUEDES, A. M. M.; ANTONIASSI, R.; GALDEANO, M. C.; GRIMALDI, R.; CARVALHO, M. G. DE; WILHELM, A. E. |
Afiliação: |
ANDREA MADALENA MACIEL GUEDES, CTAA; ROSEMAR ANTONIASSI, CTAA; MELICIA CINTIA GALDEANO, CTAA; UNICAMP; UFRRJ; ALLAN EDUARDO WILHELM, CTAA. |
Título: |
Physical and chemical characterization of interesterified Brazilian Pequi oil. |
Ano de publicação: |
2016 |
Fonte/Imprenta: |
In: AOCS ANNUAL MEETING & EXPO, 107., 2016, Salt Lake City, Utah. Experience the science and business dynamics driving the global fats and oils industries: abstracts. Urbana: AOCS, 2016. |
Páginas: |
p. 15 |
Idioma: |
Inglês |
Palavras-Chave: |
Camb; Pequi fruit; Pequi oil; Pequi pulp. |
Thesagro: |
Caryocar Brasiliense. |
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
Marc: |
LEADER 00794nam a2200229 a 4500 001 2057805 005 2016-12-02 008 2016 bl uuuu u00u1 u #d 100 1 $aGUEDES, A. M. M. 245 $aPhysical and chemical characterization of interesterified Brazilian Pequi oil.$h[electronic resource] 260 $aIn: AOCS ANNUAL MEETING & EXPO, 107., 2016, Salt Lake City, Utah. Experience the science and business dynamics driving the global fats and oils industries: abstracts. Urbana: AOCS$c2016 300 $ap. 15 650 $aCaryocar Brasiliense 653 $aCamb 653 $aPequi fruit 653 $aPequi oil 653 $aPequi pulp 700 1 $aANTONIASSI, R. 700 1 $aGALDEANO, M. C. 700 1 $aGRIMALDI, R. 700 1 $aCARVALHO, M. G. DE 700 1 $aWILHELM, A. E.
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