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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sul. Para informações adicionais entre em contato com cppsul.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sul. |
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Data corrente: |
02/09/2021 |
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Data da última atualização: |
02/09/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
FERREIRA, C. E. R.; CAMPOS, G. S.; SCHMIDT, P. I.; SOLLERO, B. P.; GOULARTE, K. L.; CORCINI, C. D.; GASPERIN, B. G.; LUCIA JUNIOR, T.; BOLIGON, A. A.; CARDOSO, F. F. |
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Afiliação: |
CARLOS E. R. FERREIRA, UFPEL; GABRIEL S. CAMPOS, UFPEL; PATRICIA I. SCHMIDT, UNESP; BRUNA PENA SOLLERO, CPPSUL; KARINA L. GOULARTE, UFPEL; CARINE D. CORCINI, UFPEL; BERNARDO G. GASPERIN, UFPEL; THOMAZ LUCIA JUNIOR, UFPEL; ARIONE A. BOLIGON, UFPEL; FERNANDO FLORES CARDOSO, CPPSUL. |
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Título: |
Genome-wide association and genomic prediction for scrotal circumference in Hereford and Braford bulls. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Theriogenology, v. 172, p. 268-280, Sept. 2021. |
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DOI: |
https://doi.org/10.1016/j.theriogenology.2021.07.007 |
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Idioma: |
Inglês |
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Conteúdo: |
Scrotal circumference (SC) is widely used as a selection criterion for bulls in breeding programs, since it is easily assessed and correlated with several desirable reproductive traits. The objectives of this study were: to perform a genome-wide association study (GWAS) to identify genomic regions associated with SC adjusted for age (SCa) and for both age and weight (SCaw); to select Tag SNPs from GWAS to construct low-density panel for genomic prediction; and to compare the prediction accuracy of the SC through different methods for Braford and Hereford bulls from the same genetic breeding program. Data of SC from 18,172 bulls (30.4 ± 3.7 cm) and of genotypes from 131 sires and 3,545 animals were used. From GWAS, the top 1% of 1-Mb windows were observed on chromosome (BTA) 2, 20, 7, 8, 15, 3, 16, 27, 6 and 8 for SCa and on BTA 8, 15, 16, 21, 19, 2, 6, 5 and 10 for SCaw, representing 17.4% and 18.8% of the additive genetic variance of SCa and SCaw, respectively. The MeSH analysis was able to translate genomic information providing biological meanings of more specific gene functions related to the SCa and SCaw. The genomic enhancement methods, especially single step GBLUP, that combined phenotype and pedigree data with direct genomic values generated gains in accuracy in relation to pedigree BLUP, suggesting that genomic predictions should be applied to improve genetic gain and to narrow the generation interval compared to traditional methods. The proposed Tag-SNP panels may be useful for lower-cost commercial genomic prediction applications in the future, when the number of bulls in the reference population increases for SC in Hereford and Braford breeds. MenosScrotal circumference (SC) is widely used as a selection criterion for bulls in breeding programs, since it is easily assessed and correlated with several desirable reproductive traits. The objectives of this study were: to perform a genome-wide association study (GWAS) to identify genomic regions associated with SC adjusted for age (SCa) and for both age and weight (SCaw); to select Tag SNPs from GWAS to construct low-density panel for genomic prediction; and to compare the prediction accuracy of the SC through different methods for Braford and Hereford bulls from the same genetic breeding program. Data of SC from 18,172 bulls (30.4 ± 3.7 cm) and of genotypes from 131 sires and 3,545 animals were used. From GWAS, the top 1% of 1-Mb windows were observed on chromosome (BTA) 2, 20, 7, 8, 15, 3, 16, 27, 6 and 8 for SCa and on BTA 8, 15, 16, 21, 19, 2, 6, 5 and 10 for SCaw, representing 17.4% and 18.8% of the additive genetic variance of SCa and SCaw, respectively. The MeSH analysis was able to translate genomic information providing biological meanings of more specific gene functions related to the SCa and SCaw. The genomic enhancement methods, especially single step GBLUP, that combined phenotype and pedigree data with direct genomic values generated gains in accuracy in relation to pedigree BLUP, suggesting that genomic predictions should be applied to improve genetic gain and to narrow the generation interval compared to traditional methods. The proposed Tag-SNP panels may ... Mostrar Tudo |
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Palavras-Chave: |
Desempenho reprodutivo; Predição genômica. |
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Thesagro: |
Bovino; Gado de Corte; Performance. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02599naa a2200301 a 4500
001 2134027
005 2021-09-02
008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.theriogenology.2021.07.007$2DOI
100 1 $aFERREIRA, C. E. R.
245 $aGenome-wide association and genomic prediction for scrotal circumference in Hereford and Braford bulls.$h[electronic resource]
260 $c2021
520 $aScrotal circumference (SC) is widely used as a selection criterion for bulls in breeding programs, since it is easily assessed and correlated with several desirable reproductive traits. The objectives of this study were: to perform a genome-wide association study (GWAS) to identify genomic regions associated with SC adjusted for age (SCa) and for both age and weight (SCaw); to select Tag SNPs from GWAS to construct low-density panel for genomic prediction; and to compare the prediction accuracy of the SC through different methods for Braford and Hereford bulls from the same genetic breeding program. Data of SC from 18,172 bulls (30.4 ± 3.7 cm) and of genotypes from 131 sires and 3,545 animals were used. From GWAS, the top 1% of 1-Mb windows were observed on chromosome (BTA) 2, 20, 7, 8, 15, 3, 16, 27, 6 and 8 for SCa and on BTA 8, 15, 16, 21, 19, 2, 6, 5 and 10 for SCaw, representing 17.4% and 18.8% of the additive genetic variance of SCa and SCaw, respectively. The MeSH analysis was able to translate genomic information providing biological meanings of more specific gene functions related to the SCa and SCaw. The genomic enhancement methods, especially single step GBLUP, that combined phenotype and pedigree data with direct genomic values generated gains in accuracy in relation to pedigree BLUP, suggesting that genomic predictions should be applied to improve genetic gain and to narrow the generation interval compared to traditional methods. The proposed Tag-SNP panels may be useful for lower-cost commercial genomic prediction applications in the future, when the number of bulls in the reference population increases for SC in Hereford and Braford breeds.
650 $aBovino
650 $aGado de Corte
650 $aPerformance
653 $aDesempenho reprodutivo
653 $aPredição genômica
700 1 $aCAMPOS, G. S.
700 1 $aSCHMIDT, P. I.
700 1 $aSOLLERO, B. P.
700 1 $aGOULARTE, K. L.
700 1 $aCORCINI, C. D.
700 1 $aGASPERIN, B. G.
700 1 $aLUCIA JUNIOR, T.
700 1 $aBOLIGON, A. A.
700 1 $aCARDOSO, F. F.
773 $tTheriogenology$gv. 172, p. 268-280, Sept. 2021.
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Embrapa Pecuária Sul (CPPSUL) |
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| 5. |  | CARDOSO, F. F.; LASKE, C. H.; SEVERO, L. K.; GENRO NETO, J. S.; FARIA, A. L. L.; RODRIGUES, P. F. Desempenho do nascimento ao sobreano de bovinos com diferentes composições genéticas criados no Sul do Brasil. In: REUNIÓN BIENAL [DE LA] ASOCIACIÓN LATINOAMERICANA DE PRODUCCIÓN ANIMAL, 21., 2009, San Juan. Producción animal en tiempos de crisis: memórias... San Juan: ALPA, 2009. p. 120-123 1 CD-ROM. Suplemento 1. Resumo expandido.| Tipo: Artigo em Anais de Congresso / Nota Técnica |
| Biblioteca(s): Embrapa Pecuária Sul. |
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| 6. | | IBELLI, A. M. G.; CARDOSO, F. F.; GENRO NETO, J. S.; OLIVEIRA, M. C. de S.; REGITANO, L. C. de A. Identificação de genes diferencialmente expressos em linfonodos de bovinos com diferentes níveis de resistência ao carrapato Rhipicephalus (Boophilus) microplus. In: WORKSHOP DA REDE GENÔMICA ANIMAL, 1., 2009, Fortaleza. Anais... Fortaleza, Rede Genômica Animal, 2009.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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