| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com rosangela.lacerda@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Gado de Leite. |
|
Data corrente: |
18/02/2019 |
|
Data da última atualização: |
24/01/2023 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
TRÍBULO, P.; BALZANO-NOGUEIRA, L.; CONESA, A.; SIQUEIRA, L. G. B.; HANSEN, P. J. |
|
Afiliação: |
PAULA TRÍBULO, University of Florida, Gainesville, Florida; LEANDRO BALZANO-NOGUEIRA, University of Florida, Gainesville, Florida; ANA CONESA, University of Florida, Gainesville, Florida; LUIZ GUSTAVO BRUNO SIQUEIRA, CNPGL; PETER J. HANSEN, University of Florida, Gainesville, Florida. |
|
Título: |
Changes in the uterine metabolome of the cow during the first 7 days after estrus. |
|
Ano de publicação: |
2019 |
|
Fonte/Imprenta: |
Molecular Reproduction and Development, v. 86, n. 1, p. 75-87, 2019. |
|
DOI: |
10.1002/mrd.23082 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Abstract The uterine microenvironment during the first 7 days after ovulation accommodates and facilitates sperm transit to the oviduct and constitutes the sole source of nutrients required for the development of preimplantation embryos. Knowledge of the composition of uterine fluid is largely incomplete. Using untargeted mass spectrometry, we characterized the uterine metabolome during the first 7 days of the estrous cycle. Bovine uteri were collected on Days 0 (N = 4), 3 ( N = 4), 5 ( N = 3), and 7 ( N = 4) relative to ovulation and flushed with Dulbecco's phosphate-buffered saline. A total of 1,993 molecular features were detected of which 184 peaks with putative identification represent 147 unique metabolites, including amino acids, benzoic acids, lipid molecules, carbohydrates, purines, pyrimidines, vitamins, and other intermediate and secondary metabolites. Results revealed changes in the uterine metabolome as the cow transitions from ovulation to Day 7 of the estrous cycle. The majority of metabolites that changed with day reached maximum intensity on either Day 5 or 7 relative to ovulation. Moreover, several metabolites found in the uterine fluid have signaling capabilities and some have been shown to affect preimplantation embryonic development. In conclusion, the metabolome of the bovine uterus changes during early stages of the estrous cycle and is likely to participate in the regulation of preimplantation embryonic development. Data reported here will serve as the basis for future studies aiming to evaluate maternal regulation of preimplantation embryonic development and optimal conditions for the culture of embryos. MenosAbstract The uterine microenvironment during the first 7 days after ovulation accommodates and facilitates sperm transit to the oviduct and constitutes the sole source of nutrients required for the development of preimplantation embryos. Knowledge of the composition of uterine fluid is largely incomplete. Using untargeted mass spectrometry, we characterized the uterine metabolome during the first 7 days of the estrous cycle. Bovine uteri were collected on Days 0 (N = 4), 3 ( N = 4), 5 ( N = 3), and 7 ( N = 4) relative to ovulation and flushed with Dulbecco's phosphate-buffered saline. A total of 1,993 molecular features were detected of which 184 peaks with putative identification represent 147 unique metabolites, including amino acids, benzoic acids, lipid molecules, carbohydrates, purines, pyrimidines, vitamins, and other intermediate and secondary metabolites. Results revealed changes in the uterine metabolome as the cow transitions from ovulation to Day 7 of the estrous cycle. The majority of metabolites that changed with day reached maximum intensity on either Day 5 or 7 relative to ovulation. Moreover, several metabolites found in the uterine fluid have signaling capabilities and some have been shown to affect preimplantation embryonic development. In conclusion, the metabolome of the bovine uterus changes during early stages of the estrous cycle and is likely to participate in the regulation of preimplantation embryonic ... Mostrar Tudo |
|
Palavras-Chave: |
Histotroph; Maternal-embryo crosstalk. |
|
Thesaurus Nal: |
Endometrium; Metabolome. |
|
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
|
Marc: |
LEADER 02392naa a2200229 a 4500
001 2106149
005 2023-01-24
008 2019 bl uuuu u00u1 u #d
024 7 $a10.1002/mrd.23082$2DOI
100 1 $aTRÍBULO, P.
245 $aChanges in the uterine metabolome of the cow during the first 7 days after estrus.$h[electronic resource]
260 $c2019
520 $aAbstract The uterine microenvironment during the first 7 days after ovulation accommodates and facilitates sperm transit to the oviduct and constitutes the sole source of nutrients required for the development of preimplantation embryos. Knowledge of the composition of uterine fluid is largely incomplete. Using untargeted mass spectrometry, we characterized the uterine metabolome during the first 7 days of the estrous cycle. Bovine uteri were collected on Days 0 (N = 4), 3 ( N = 4), 5 ( N = 3), and 7 ( N = 4) relative to ovulation and flushed with Dulbecco's phosphate-buffered saline. A total of 1,993 molecular features were detected of which 184 peaks with putative identification represent 147 unique metabolites, including amino acids, benzoic acids, lipid molecules, carbohydrates, purines, pyrimidines, vitamins, and other intermediate and secondary metabolites. Results revealed changes in the uterine metabolome as the cow transitions from ovulation to Day 7 of the estrous cycle. The majority of metabolites that changed with day reached maximum intensity on either Day 5 or 7 relative to ovulation. Moreover, several metabolites found in the uterine fluid have signaling capabilities and some have been shown to affect preimplantation embryonic development. In conclusion, the metabolome of the bovine uterus changes during early stages of the estrous cycle and is likely to participate in the regulation of preimplantation embryonic development. Data reported here will serve as the basis for future studies aiming to evaluate maternal regulation of preimplantation embryonic development and optimal conditions for the culture of embryos.
650 $aEndometrium
650 $aMetabolome
653 $aHistotroph
653 $aMaternal-embryo crosstalk
700 1 $aBALZANO-NOGUEIRA, L.
700 1 $aCONESA, A.
700 1 $aSIQUEIRA, L. G. B.
700 1 $aHANSEN, P. J.
773 $tMolecular Reproduction and Development$gv. 86, n. 1, p. 75-87, 2019.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Gado de Leite (CNPGL) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 10 | |
| 2. |  | ROSA, D. P. da; REICHERT, J. M.; MENTGES, M. I.; ROSA, V. T. da; VIEIRA, D. A.; REINERT, D. J. Demanda de tração e propriedades físicas de um Argissolo em diferentes manejos e intensidades de tráfego. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 47, n. 1, p. 118-126, jan. 2012. Título em inglês: Draught requirement and physical properties in a Hapludalf at different management and traffic intensity levels.| Biblioteca(s): Embrapa Unidades Centrais. |
|    |
| 3. | | ZENI, R.; ROSA. D. P. da; PESINI, F.; FINCATTO, D.; BAMBERG, A. L.; MARTINAZZO, R.; SILVEIRA, C. A. P. Desenvolvimento de aveia branca em diferentes manejos fisicos e quimicos em nitossolo. In: CONGRESO LATINOAMERICANO DE LA CIENCIA DEL SUELO, 20.; CONGRESO PERUANO DE LA CIENCIA DEL SUELO, 16., 2014, Cusco. Educar para preservar el suelo y conservar la vida en la tierra: [anales]. Cusco: Sociedade Latinoamericana de la Sciencia del Suelo: Sociedade Peruana de la Sciencia del Suelo, 2014.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Clima Temperado. |
| |
| 4. | | MENTGES, M. I.; REICHERT, J. M.; ROSA, D. P. da; VIEIRA, D. A.; ROSA, V. T. da; REINERT, D. J. Propriedades físico-hídricas do solo e demanda energética de haste escarificadora em Argissolo compactado. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 45, n. 3, p. 315-321, mar. 2010 Título em inglês: Soil physicohydric properties and chisel energy demand in a compacted Alfisol.| Biblioteca(s): Embrapa Unidades Centrais. |
| |
| 5. | | ROSA, D. P. da; REICHERT, J. M.; SATTLER, A.; REINERT, D. J.; MENTGES, M. I.; VIEIRA, D. A. Relação entre solo e haste sulcadora de semeadora em Latossolo escarificado em diferentes épocas. Pesquisa Agropecuária Brasileira, Brasilia, DF, v. 43, n. 3, p. 395-400, mar. 2008.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Internacional - A |
| Biblioteca(s): Embrapa Trigo; Embrapa Unidades Centrais. |
| |
| 6. | | NAVROSKI, M. C.; PEREIRA, M. de O.; BORSOI, G. A.; KALIL FILHO, A. N.; NASCIMENTO, B.; ROSA, D. P. da. Tolerância ao frio e características silviculturais do cedro-australiano no sul do Brasil. Pesquisa Florestal Brasileira, Colombo, v. 37, n. 89, p. 47-54, jan./mar. 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 3 |
| Biblioteca(s): Embrapa Florestas. |
| |
| 7. | | ROSA, D. P. da; ROSA, V. T. da; REICHERT, J. M.; REINERT, D. J.; SATTLER, A.; MENTGES, M. I.; VIEIRA, D. A. Evolução da compressibilidade de um latossolo argiloso sob semeadura direta. In: CONGRESSO BRASILEIRO DE CIÊNCIA DO SOLO, 31., 2007, Gramado. Conquistas e desafios da ciência do solo brasileiro. Porto Alegre: SBCS, Núcleo Regional Sul: UFRGS, 2007. 1 CD-ROM. 5 p.| Tipo: Artigo em Anais de Congresso / Nota Técnica |
| Biblioteca(s): Embrapa Trigo. |
| |
| 8. | | REICHERT, J. M.; ROSA, V. T. da; VOGELMANN, E. S.; ROSA, D. P. da; HORN, R.; REINERT, D. J.; SATTLER, A.; DENARDIN, J. E. Conceptual framework for capacity and intensity physical soil properties affected by short and long-term (14 years) continuous no-tillage and controlled traffic. Soil & Tillage Research, Amsterdam, v. 158, p. 123-136, 2016.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Trigo. |
| |
| 9. | | ROSA, V. T. da; ROSA, D. P. da; SATTLER, A.; MENTGES, M. I.; VIEIRA, D. A.; REICHERT, J. M.; REINERT, D. J. Alteração da condutividade hidráulica saturada do solo em áreas com diferentes níveis de tráfego de máquinas e prazos de adoção do sistema plantio direto. In: REUNIÃO BRASILEIRA DE MANEJO E CONSERVAÇÃO DO SOLO E DA ÁGUA, 17., 2008, Rio de Janeiro. Manejo e conservação do solo e da água no contexto das mudanças ambientais: anais. Rio de Janeiro: UFRRJ: Embrapa Solos; Seropédica: Embrapa Agrobiologia, 2008. 4 p.| Biblioteca(s): Embrapa Trigo. |
| |
| 10. | | TERRA, L. A.; SCHWAB, S.; TEIXEIRA, K. R. dos S.; ARAUJO, J. L. S. de; CHAVES, M. S.; FREITAS, H. R. B. de; CRIVELARO, A. L. R.; NUNES, A. B. de C.; SANTOS, C. M. dos; ROSA, D. P. da S.; PADILHA, D. da S.; SILVA, E. da; MENDES, V. S.; FARINELLI, L.; CRUZ, L. M.; BALDANI, J. I. Draft genome sequence of Nitrospirillum amazonense strain CBAmC, a nitrogen fixer and plant growth promoter isolated from sugarcane, reveal bacterial potential benefits to cane culture In: INTERNATIONAL PGPR WORKSHOP, 10., Liége, 2015. Program and abstract book. Liége: Université de Liége, 2015.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agrobiologia. |
| |
| Registros recuperados : 10 | |
|
| Expressão de busca inválida. Verifique!!! |
|
|
