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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
22/06/2017 |
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Data da última atualização: |
22/06/2017 |
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Autoria: |
DOBSON, H.; ESSAWY, S. A.; ALAM, M. G. S. |
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Título: |
Suppression of LH response to gonadotrophin-releasing hormone or oestradiol by ACTH(1-24) treatment in anoestrous ewes. |
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Ano de publicação: |
1988 |
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Fonte/Imprenta: |
Journal of Endocrinology, v. 118, n. 2, p.193-197, Aug. 1988. |
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DOI: |
10.1677/joe.0.1180193 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Stress is known to result in lowered female reproductive efficiency. The objective of this study was to examine how increased pituitary-adrenal activity may influence gonadotrophin release in anoestrous ewes. Various doses (0.06-1.0 mg) of a synthetic adrenocorticotrophic hormone (ACTH(1-24)) preparation were injected into ewes 30 min or 3 h before an i.v. injection of 500 ng gonadotrophin-releasing hormone (GnRH). The LH response to GnRH given 30 min after ACTH(1-24) was similar to that after GnRH alone, whereas the response 3 h after ACTH(1-24) was significantly lower, irrespective of the dose of ACTH(1-24). At 30 min and 3 h after ACTH(1-24) the concentrations of cortisol exceeded 50 nmol/l compared with baseline values of less than 10 nmol/l. The effect of ACTH(1-24) on oestradiol-induced LH release was also examined. Those ewes receiving 0.8 mg ACTH(1-24) depot and 50 micrograms oestradiol benzoate simultaneously had a preovulatory-type increase in LH 14-20 h later, similar to when oestradiol benzoate was given alone. None of the ewes receiving an additional 0.8 mg ACTH(1-24) depot 10 h after oestradiol benzoate had increases in LH concentration. The cortisol concentrations in all ewes receiving either one or two injections of ACTH(1-24) were greater than 35 nmol/l at 10 h after the oestradiol injection. However, concentrations of progesterone increased from 0.9 +/- 0.3 (S.E.M.) nmol/l at the time of the second ACTH(1-24) injection to 2.1 +/- 0.3 nmol/l after 2 h. MenosAbstract: Stress is known to result in lowered female reproductive efficiency. The objective of this study was to examine how increased pituitary-adrenal activity may influence gonadotrophin release in anoestrous ewes. Various doses (0.06-1.0 mg) of a synthetic adrenocorticotrophic hormone (ACTH(1-24)) preparation were injected into ewes 30 min or 3 h before an i.v. injection of 500 ng gonadotrophin-releasing hormone (GnRH). The LH response to GnRH given 30 min after ACTH(1-24) was similar to that after GnRH alone, whereas the response 3 h after ACTH(1-24) was significantly lower, irrespective of the dose of ACTH(1-24). At 30 min and 3 h after ACTH(1-24) the concentrations of cortisol exceeded 50 nmol/l compared with baseline values of less than 10 nmol/l. The effect of ACTH(1-24) on oestradiol-induced LH release was also examined. Those ewes receiving 0.8 mg ACTH(1-24) depot and 50 micrograms oestradiol benzoate simultaneously had a preovulatory-type increase in LH 14-20 h later, similar to when oestradiol benzoate was given alone. None of the ewes receiving an additional 0.8 mg ACTH(1-24) depot 10 h after oestradiol benzoate had increases in LH concentration. The cortisol concentrations in all ewes receiving either one or two injections of ACTH(1-24) were greater than 35 nmol/l at 10 h after the oestradiol injection. However, concentrations of progesterone increased from 0.9 +/- 0.3 (S.E.M.) nmol/l at the time of the second ACTH(1-24) injection to 2.1 +/- 0.3 nmol/l after ... Mostrar Tudo |
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Palavras-Chave: |
Anoestrus; LH; Releasing hormones. |
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Thesagro: |
Estradiol. |
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Thesaurus Nal: |
Ewes; Pharmacology; Physiology; Pituitary hormones; Sheep. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
null
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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| Registros recuperados : 6 | |
| 1. |  | ÁVILA, S. L. C. de; OLIVEIRA, C. O. de; RODRIGUES, T. A.; TAVARES, A. T.; SOARES, S. L.; COSTA, S. M. L. de C. da; FERRAZ, A.; LEDUR, M. C.; ANCIUTI, M. A.; BONGALHARDO, D. C. Replacement of corn and soybean meal with corn gluten meal on rooster's diet. Turkish Journal of Veterinary and Animal Sciences, v. 44, p. 798-804, 2020.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 2 |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| 3. | | CÂMARA, A. R.; PELUZIO, J. M.; FERREIRA, L. U.; MELLO FILHO, O. L. de; SOARES, S. L. Diallel analysis and combining ability in crosses between Glycine max and Glycine soja aiming at improving protein, oil and fatty acid contente. Revista Observatorio de la Economia Latinoamericana, v. 22, n. 12, p. 1-19, 2024. Título em português: Análise dialélica e capacidade de combinação em cruzamentos entre Glycine max e Glycine soja visando o melhoramento do teor de proteína, óleo e ácidos graxos. Título em espanhol: Análisis dialélico y capacidad...| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 4 |
| Biblioteca(s): Embrapa Soja. |
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| 4. | | SOARES, S. L.; ANCIUTIA, A. N.; DIAS, L.; CORCINI, C. D.; VARELA JÚNIOR, A. S.; KOMNINOU, E. R.; TEBALDI, M. L.; MARQUES, M. G.; FONSECA, F. M. da; LUCIA JUNIOR, T. Safety assessment of poly (N-vinylcaprolactam) as a potential drug carrier in extenders for boar sperm cryopreservation. Toxicology in Vitro, v. 65, n. 104766, 2020.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| 5. | | SOARES, S. L.; BRITO, C. R. C.; ANCIUTI, A. N.; GATTI, N. C.; CORCINI, C. D.; VARELA JÚNIOR, A. S.; MARQUES, M. G.; FONSECA, F. M. da; KOMNINOU, E. R.; LÚCIA JÚNIOR, T. Nanocarried antioxidants in freezing extenders for boar spermatozoa. Andrologia, ed. 14199, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| Registros recuperados : 6 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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