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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
15/03/2017 |
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Data da última atualização: |
15/03/2017 |
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Autoria: |
ISHINO, S.; MATSUDA, I.; YAMAMOTO, H.; YOSHINO, T.; SENTSUI, H.; MIZUNO, Y.; KONO, Y. |
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Título: |
Pathological findings of two types of lymphoid malignancy in sheep inoculated with bovine leukemia virus. |
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Ano de publicação: |
1989 |
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Fonte/Imprenta: |
Japanese Journal of Veterinary Science v. 51, n. 4, p. 749-756, Aug. 1989. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Different types of lymphoid malignancy were observed in two sheep inoculated with BLV-containing materials. Sheep 1 showed severe leukemic change in the peripheral blood and splenomegaly but lymphosarcoma in the lymph nodes was absent. Sheep 2 had lymphosarcoma in the lymph nodes and various organs. Neoplastic cells had B-cell marker in both cases and a few neoplastic cells contained intracytoplasmic IgM in sheep 2. It was presumed that B-cells might be transformed into neoplastic cells on the way of their differentiation. Some of neoplastic cells might have ability of immunoglobulin-production in sheep 2.
PMID: 2555619 |
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Palavras-Chave: |
Bovine leukaemia virus; Bovine leukosis; Cell transformation; Experimental infection; Infecção experimental; Intracytoplasmic immunoglobulin; Leukaemia; Nódulo linfático; Ovine lymphosarcoma; Surface immunoglobulin. |
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Thesagro: |
Doença animal; Leucemia; Linfossarcoma; Ovino. |
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Thesaurus Nal: |
Lymph nodes; Sheep. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
null
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
