Registro Completo |
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
15/03/2017 |
Data da última atualização: |
15/03/2017 |
Autoria: |
ISHINO, S.; MATSUDA, I.; YAMAMOTO, H.; YOSHINO, T.; SENTSUI, H.; MIZUNO, Y.; KONO, Y. |
Título: |
Pathological findings of two types of lymphoid malignancy in sheep inoculated with bovine leukemia virus. |
Ano de publicação: |
1989 |
Fonte/Imprenta: |
Japanese Journal of Veterinary Science v. 51, n. 4, p. 749-756, Aug. 1989. |
Idioma: |
Inglês |
Conteúdo: |
Abstract: Different types of lymphoid malignancy were observed in two sheep inoculated with BLV-containing materials. Sheep 1 showed severe leukemic change in the peripheral blood and splenomegaly but lymphosarcoma in the lymph nodes was absent. Sheep 2 had lymphosarcoma in the lymph nodes and various organs. Neoplastic cells had B-cell marker in both cases and a few neoplastic cells contained intracytoplasmic IgM in sheep 2. It was presumed that B-cells might be transformed into neoplastic cells on the way of their differentiation. Some of neoplastic cells might have ability of immunoglobulin-production in sheep 2.
PMID: 2555619 |
Palavras-Chave: |
Bovine leukaemia virus; Bovine leukosis; Cell transformation; Experimental infection; Infecção experimental; Intracytoplasmic immunoglobulin; Leukaemia; Nódulo linfático; Ovine lymphosarcoma; Surface immunoglobulin. |
Thesagro: |
Doença animal; Leucemia; Linfossarcoma; Ovino. |
Thesaurus Nal: |
Lymph nodes; Sheep. |
Categoria do assunto: |
H Saúde e Patologia |
Marc: |
LEADER 01731naa a2200385 a 4500 001 2067046 005 2017-03-15 008 1989 bl uuuu u00u1 u #d 100 1 $aISHINO, S. 245 $aPathological findings of two types of lymphoid malignancy in sheep inoculated with bovine leukemia virus. 260 $c1989 520 $aAbstract: Different types of lymphoid malignancy were observed in two sheep inoculated with BLV-containing materials. Sheep 1 showed severe leukemic change in the peripheral blood and splenomegaly but lymphosarcoma in the lymph nodes was absent. Sheep 2 had lymphosarcoma in the lymph nodes and various organs. Neoplastic cells had B-cell marker in both cases and a few neoplastic cells contained intracytoplasmic IgM in sheep 2. It was presumed that B-cells might be transformed into neoplastic cells on the way of their differentiation. Some of neoplastic cells might have ability of immunoglobulin-production in sheep 2. PMID: 2555619 650 $aLymph nodes 650 $aSheep 650 $aDoença animal 650 $aLeucemia 650 $aLinfossarcoma 650 $aOvino 653 $aBovine leukaemia virus 653 $aBovine leukosis 653 $aCell transformation 653 $aExperimental infection 653 $aInfecção experimental 653 $aIntracytoplasmic immunoglobulin 653 $aLeukaemia 653 $aNódulo linfático 653 $aOvine lymphosarcoma 653 $aSurface immunoglobulin 700 1 $aMATSUDA, I. 700 1 $aYAMAMOTO, H. 700 1 $aYOSHINO, T. 700 1 $aSENTSUI, H. 700 1 $aMIZUNO, Y. 700 1 $aKONO, Y. 773 $tJapanese Journal of Veterinary Science$gv. 51, n. 4, p. 749-756, Aug. 1989.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |