Data/hora: 18/04/2024 15:46:05

Biblioteca(s): 	Embrapa Caprinos e Ovinos.	
Data corrente: 	09/06/2017	
Data da última atualização: 	09/06/2017	
Autoria: 	KING, J. A.; MILLAR, R. P.	
Título: 	Decapeptide luteinizing hormone releasing hormone in ovine pineal gland.	
Ano de publicação: 	1981	
Fonte/Imprenta: 	Journal of Endocrinology, v. 90, n. 3, p. 405-414, Dec. 1981.	
DOI: 	10.1677/joe.0.0910405	
Idioma: 	Francês	
Conteúdo: 	Abstract: Ovine pineal gland extracts were examined throughout the year for content and molecular form of immunoreactive (IMR) LH releasing hormone (LH-RH). The content of IMR LH-RH in pineal glands collected in spring and summer was 160-2230 pg/gland, while the content in pineal glands collected in autumn and winter was lower (31-39 pg/gland). Pineal gland IMR LH-RH, purified by affinity and Sephadex G-25 chromatography, yielded displacement curves parallel to those of hypothalamic IMR LH-RH and synthetic LH-RH in radioimmunoassays employing four antisera which require different regions of the decapeptide for effective binding, suggesting considerable similarities in the structure of the molecule. The majority of pineal gland IMR LH-RH behaved identically to hypothalamic IMR LH-RH and synthetic LH-RH on gel filtration, cation exchange chromatography, high-pressure liquid chromatography and cellulose thin-layer chromatography. However, a small amount of a less positively charged LH-RH species was also present in all pineal gland extracts. Our findings indicate that hypothalamic decapeptide LH-RH occurs in the ovine pineal gland.	
Palavras-Chave: 	LH; Pineal gland.	
Thesaurus Nal: 	Chromatography; Ewes; Hypothalamus; Metabolism; Peptides; Seasons; Sheep.	
Categoria do assunto: 	L Ciência Animal e Produtos de Origem Animal	
Registro original: 	Embrapa Caprinos e Ovinos (CNPC)	
Exemplares: 	CNPC - (33757-1) - ADD - AP - PP -  -  -  - DIS