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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital. |
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Data corrente: |
20/04/2006 |
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Data da última atualização: |
27/02/2024 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
NESHICH, G.; FALCAO, P. R. K.; YAMAGISHI, M. E. B.; OLIVEIRA, S. R. de M.; MAZONI, I.; SANTOS, E. H. dos; VIEIRA, F. D.; CRUZ, S. A. B. da; MANCINI, A. L.; JARDINE, J. G.; HIGA, R. H. |
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Afiliação: |
GORAN NESIC, CNPTIA; PAULA REGINA KUSER FALCAO, CNPTIA; MICHEL EDUARDO BELEZA YAMAGISHI, CNPTIA; STANLEY ROBSON DE MEDEIROS OLIVEIRA, CNPTIA; IVAN MAZONI, CNPTIA; EDGARD HENRIQUE DOS SANTOS, CNPTIA; FABIO DANILO VIEIRA, CNPTIA; SERGIO APARECIDO BRAGA DA CRUZ, CNPTIA; ADAUTO LUIZ MANCINI, CNPTIA; JOSE GILBERTO JARDINE, CNPM; ROBERTO HIROSHI HIGA, CNPTIA. |
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Título: |
What makes the active site amino acids so different from the others: defining the structural descriptors specific for activity. |
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Ano de publicação: |
2005 |
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Fonte/Imprenta: |
In: X-MEETING; INTERNATIONAL CONFERENCE OF THE AB3C, 1., 2005, Caxambu. [Proceedings...]. [S.l.]: Associação Brasileira de Bioinformática e Biologia Computacional, 2005. |
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Páginas: |
p. 149. |
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Idioma: |
Inglês |
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Notas: |
Na publicação: Paula Kuser, Michel Yamagishi, Stanley Oliveira, Edgard Santos, Fabio Vieira, Sergio Cruz, Adauto Mancini, Roberto Higa. X-meeting 2005. Presented Posters. |
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Conteúdo: |
We describe in this paper some of the new features available in Diamond STING Suite. Also, we emphasize here the main difference which continues to work in favor of the STING and separates it from the other servers belonging to this category also available on the Internet - the capability to present the largest number of descriptors for the sequence, structure, function, stability and binding in a concise and visually compelling way, as well as the capability to select/focus for/at those residues which satisfy a user defined parameter/descriptor values. This feature allows that some very interesting and important questions can be answered, such as: Is there a set of parameters (protein structure descriptors) which can define UNIQUELY an amino acid ensemble coinciding with the active site of a given protein or coinciding with amino acids identified experimentally as crucial for the folding / stability. We present here an example where by combining selected ranges for a number of structure parameters we have obtained at the end of a Select procedure an ensemble of which coincides with the critical residues identified experimentally as the activity essential residues for number of protein families. The Select procedure used only few parameters and their numerical values/regions to achieve this objective. |
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Palavras-Chave: |
Bioinformática; Descritores. |
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Thesagro: |
Aminoácido. |
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Thesaurus Nal: |
Amino acids; Bioinformatics. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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Marc: |
LEADER 02526nam a2200313 a 4500
001 1008738
005 2024-02-27
008 2005 bl uuuu u00u1 u #d
100 1 $aNESHICH, G.
245 $aWhat makes the active site amino acids so different from the others$bdefining the structural descriptors specific for activity.$h[electronic resource]
260 $aIn: X-MEETING; INTERNATIONAL CONFERENCE OF THE AB3C, 1., 2005, Caxambu. [Proceedings...]. [S.l.]: Associação Brasileira de Bioinformática e Biologia Computacional$c2005
300 $ap. 149.
500 $aNa publicação: Paula Kuser, Michel Yamagishi, Stanley Oliveira, Edgard Santos, Fabio Vieira, Sergio Cruz, Adauto Mancini, Roberto Higa. X-meeting 2005. Presented Posters.
520 $aWe describe in this paper some of the new features available in Diamond STING Suite. Also, we emphasize here the main difference which continues to work in favor of the STING and separates it from the other servers belonging to this category also available on the Internet - the capability to present the largest number of descriptors for the sequence, structure, function, stability and binding in a concise and visually compelling way, as well as the capability to select/focus for/at those residues which satisfy a user defined parameter/descriptor values. This feature allows that some very interesting and important questions can be answered, such as: Is there a set of parameters (protein structure descriptors) which can define UNIQUELY an amino acid ensemble coinciding with the active site of a given protein or coinciding with amino acids identified experimentally as crucial for the folding / stability. We present here an example where by combining selected ranges for a number of structure parameters we have obtained at the end of a Select procedure an ensemble of which coincides with the critical residues identified experimentally as the activity essential residues for number of protein families. The Select procedure used only few parameters and their numerical values/regions to achieve this objective.
650 $aAmino acids
650 $aBioinformatics
650 $aAminoácido
653 $aBioinformática
653 $aDescritores
700 1 $aFALCAO, P. R. K.
700 1 $aYAMAGISHI, M. E. B.
700 1 $aOLIVEIRA, S. R. de M.
700 1 $aMAZONI, I.
700 1 $aSANTOS, E. H. dos
700 1 $aVIEIRA, F. D.
700 1 $aCRUZ, S. A. B. da
700 1 $aMANCINI, A. L.
700 1 $aJARDINE, J. G.
700 1 $aHIGA, R. H.
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Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
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