Registro Completo |
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
02/12/2004 |
Data da última atualização: |
30/06/2023 |
Autoria: |
MEGARRITY, R. G.; JONES, R. J. |
Título: |
Toxicity of Leucaena leucocephala in ruminants: the effect of supplemental thyroxine on goats fed on a sole diet of Leucaena. |
Ano de publicação: |
1983 |
Fonte/Imprenta: |
Australian Journal of Agricultural Research, v. 34, p. 791-798, 1983. |
Idioma: |
Inglês |
Conteúdo: |
Abstract: Daily injections of thyroxine were ineffective in overcoming the toxic effects of feeding Leucaena to goats. The treated goats did not differ from the controls in liveweight change or body condition over the 15 weeks of feeding Leucaena and both groups of animals developed oesophageal lesions. Treated animals maintained normal serum thyroxine (T4) and triiodothyronine (T3) levels and did not exhibit the thyroid hyperplasia of the controls. An increase in the serum T4 and T3 levels of three of the control animals after 5 weeks of feeding was associated with declining mimosine concentration in the feed and the ability of the hyperplastic thyroids to produce sufficient T4. Serum analyses suggested zinc deficiency in the control animals, associated with their low thyroid status. It was concluded that the goitrogenicity of 3-hydroxy-4(1H)-pyridone (DHP) is only partly responsible for the toxicity of Leucaena to ruminants, and that the low feed intakes and low liveweight gains are related to other effects of DHP. The evidence for extra-ruminal metabolism of DHP is discussed. |
Palavras-Chave: |
Leucaena leucocephapa; Toxicidade. |
Thesagro: |
Caprino; Nutrição Animal; Tiroxina. |
Thesaurus Nal: |
Animal feeding; Forage legumes; Goats; Ruminant nutrition; Toxic substances. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
Marc: |
LEADER 01868naa a2200253 a 4500 001 1530859 005 2023-06-30 008 1983 bl uuuu u00u1 u #d 100 1 $aMEGARRITY, R. G. 245 $aToxicity of Leucaena leucocephala in ruminants$bthe effect of supplemental thyroxine on goats fed on a sole diet of Leucaena.$h[electronic resource] 260 $c1983 520 $aAbstract: Daily injections of thyroxine were ineffective in overcoming the toxic effects of feeding Leucaena to goats. The treated goats did not differ from the controls in liveweight change or body condition over the 15 weeks of feeding Leucaena and both groups of animals developed oesophageal lesions. Treated animals maintained normal serum thyroxine (T4) and triiodothyronine (T3) levels and did not exhibit the thyroid hyperplasia of the controls. An increase in the serum T4 and T3 levels of three of the control animals after 5 weeks of feeding was associated with declining mimosine concentration in the feed and the ability of the hyperplastic thyroids to produce sufficient T4. Serum analyses suggested zinc deficiency in the control animals, associated with their low thyroid status. It was concluded that the goitrogenicity of 3-hydroxy-4(1H)-pyridone (DHP) is only partly responsible for the toxicity of Leucaena to ruminants, and that the low feed intakes and low liveweight gains are related to other effects of DHP. The evidence for extra-ruminal metabolism of DHP is discussed. 650 $aAnimal feeding 650 $aForage legumes 650 $aGoats 650 $aRuminant nutrition 650 $aToxic substances 650 $aCaprino 650 $aNutrição Animal 650 $aTiroxina 653 $aLeucaena leucocephapa 653 $aToxicidade 700 1 $aJONES, R. J. 773 $tAustralian Journal of Agricultural Research$gv. 34, p. 791-798, 1983.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |